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KCNJ6 peptide :: GIRK2 / KCNJ6 Peptide

Scan QR to view Datasheet Catalog #    MBS426120 KCNJ6 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GIRK2 / KCNJ6, Peptide

 Also Known As   

GIRK2 / KCNJ6 Immunizing Peptide

 Product Synonym Names    KCNJ6; GIRK2; potassium inwardly-rectifying channel, subfamily J, member 6; BIR1; KATP2; KCNJ7; KIR3.2; MGC126596; hiGIRK2; G protein-activated inward rectifier potassium channel 2; inward rectifier potassium channel KIR3.2; potassium inwardly-; GIRK2 / KCNJ6
 Product Gene Name   

KCNJ6 peptide

[Similar Products]
 Product Synonym Gene Name    GIRK2 [Similar Products]
 Antibody/Peptide Pairs    GIRK2 / KCNJ6 peptide (MBS426120) is used for blocking the activity of GIRK2/KCNJ6 antibody (MBS421045)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-SSKLNQHA ELET
 OMIM    600877
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 Species Reactivity    Human, Mouse, Rat
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of KCNJ6 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for KCNJ6. It may not necessarily be applicable to this product.
 NCBI GI #    4504843
 NCBI GeneID    3763
 NCBI Accession #    NP_002231.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002240.4 [Other Products]
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 UniProt Secondary Accession #    Q3MJ74; Q53WW6 [Other Products]
 UniProt Related Accession #    P48051 [Other Products]
 Molecular Weight    48,451 Da
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 NCBI Official Full Name    G protein-activated inward rectifier potassium channel 2
 NCBI Official Synonym Full Names    potassium voltage-gated channel subfamily J member 6
 NCBI Official Symbol    KCNJ6 [Similar Products]
 NCBI Official Synonym Symbols   
BIR1; GIRK2; KATP2; KCNJ7; KPLBS; GIRK-2; KATP-2; KIR3.2; hiGIRK2
[Similar Products]
 NCBI Protein Information    G protein-activated inward rectifier potassium channel 2
 UniProt Protein Name    G protein-activated inward rectifier potassium channel 2
 UniProt Synonym Protein Names   
BIR1; Inward rectifier K(+) channel Kir3.2; KATP-2; Potassium channel, inwardly rectifying subfamily J member 6
 Protein Family    G protein-activated inward rectifier potassium channel
 UniProt Gene Name    KCNJ6 [Similar Products]
 UniProt Synonym Gene Names    GIRK2; KATP2; KCNJ7; GIRK-2 [Similar Products]
 UniProt Entry Name    KCNJ6_HUMAN
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 NCBI Summary for KCNJ6    This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015]
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 UniProt Comments for KCNJ6    GIRK2: This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 21q22.1

Cellular Component: Golgi apparatus; plasma membrane; voltage-gated potassium channel complex

Molecular Function: G-protein activated inward rectifier potassium channel activity; inward rectifier potassium channel activity; protein binding

Biological Process: potassium ion import; potassium ion transport

Disease: Keppen-lubinsky Syndrome
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 Research Articles on KCNJ6    1. The findings of this study suggest that variations in KCNJ6 genes are associated with both mild and severe persistent breast pain after breast cancer surgery.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with KCNJ6 peptidePathways associated with KCNJ6 peptide
 Reference Product  PubMed Publications
 GNB5 peptide  >1 publications with KCNJ6 and GNB5
 DRD2 peptide  >1 publications with KCNJ6 and DRD2
 Products by Pathway  Pathway Diagram
 Activation Of G Protein Gated Potassium Channels Pathway antibodies  Activation Of G Protein Gated Potassium Channels Pathway Diagram
 Activation Of GABAB Receptors Pathway antibodies  Activation Of GABAB Receptors Pathway Diagram
 Cholinergic Synapse Pathway antibodies  Cholinergic Synapse Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram
 G Protein Gated Potassium Channels Pathway antibodies  G Protein Gated Potassium Channels Pathway Diagram
Diseases associated with KCNJ6 peptideOrgans/Tissues associated with KCNJ6 peptide
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >37 publications with KCNJ6 and Nervous System Diseases
 Brain Diseases Antibodies  >18 publications with KCNJ6 and Brain Diseases
 Mental Disorders Antibodies  >14 publications with KCNJ6 and Mental Disorders
 Neurobehavioral Manifestations Antibodies  >13 publications with KCNJ6 and Neurobehavioral Manifestations
 Movement Disorders Antibodies  >9 publications with KCNJ6 and Movement Disorders
 Basal Ganglia Diseases Antibodies  >9 publications with KCNJ6 and Basal Ganglia Diseases
 Heart Diseases Antibodies  >4 publications with KCNJ6 and Heart Diseases
 Seizures Antibodies  >3 publications with KCNJ6 and Seizures
 Memory Disorders Antibodies  >2 publications with KCNJ6 and Memory Disorders
 Learning Disorders Antibodies  >2 publications with KCNJ6 and Learning Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >59 publications with KCNJ6 and Brain
 Lung Antibodies  >2 publications with KCNJ6 and Lung
 Testis Antibodies  >1 publications with KCNJ6 and Testis
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