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GAL80 peptide

Scan QR to view Datasheet Catalog #    MBS633737 GAL80 peptide
Unit / Price
1 mg  /  $570 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Gal80, Peptide

 Also Known As   

Gal80

 Product Gene Name   

GAL80 peptide

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: XIII; NC_001145.3 (171594..172901). Location: chromosome: XIII
 3D Structure    ModBase 3D Structure for P04387
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 Purity/Purification    0.8
 Form/Format    Supplied as a lyophilized powder.
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 Sequence (linear)    DERGNRLGQRVPKTVC
 Quality Control    HPLC, MS
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 Preparation and Storage    Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of GAL80 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for GAL80 peptide

   The Gal80p complex consists of three components encoded by GAL4,GAL80, and Gal3. These components form a herterotrimeric complex. S. cerevisiae responds to galactose as sole carbon source by activating the GAL genes. The switch from expressed to activated gene expression involves the interplay of three proteins: the activator Gal4p, the repressor Gal80p, the inducer Gal3p, and two small molecules ATP and galactose. In the absence of galactose the transcriptional activity of Gal4p is inhibited by Gal80p. The association of galactose and ATP with Gal3p promote its interaction with the Gal4p -Gal80p complex. This interaction allows Gal4p to be freed from Gal80p inhibition and activate transcription. It has also been shown that Gal1p can also relieve the Gal80 repression of Gal4p in the presence of galactose, although less efficiently than Gal3p.
 Product Categories/Family for GAL80 peptide    Molecular Biology; MB-Peptides
NCBI/Uniprot data below describe general gene information for GAL80. It may not necessarily be applicable to this product.
 NCBI GI #    6323590
 NCBI GeneID    854954
 NCBI Accession #    NP_013661.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001182409.1 [Other Products]
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 UniProt Primary Accession #    P04387 [Other Products]
 UniProt Secondary Accession #    D6VZC4 [Other Products]
 UniProt Related Accession #    P04387 [Other Products]
 Molecular Weight    48,323 Da [Similar Products]
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 NCBI Official Full Name    Gal80p
 NCBI Official Symbol    GAL80 [Similar Products]
 NCBI Protein Information    Gal80p
 UniProt Protein Name    Galactose/lactose metabolism regulatory protein GAL80
 Protein Family    Galactose/lactose metabolism regulatory protein
 UniProt Gene Name    GAL80 [Similar Products]
 UniProt Entry Name    GAL80_YEAST
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 UniProt Comments for GAL80    Function: This protein is a negative regulator for the gene expression of the lactose/galactose metabolic genes. It binds to GAL4 and so blocks transcriptional activation by it, in the absence of an inducing sugar. Ref.4

Subunit structure: Monomer. Ref.4

Miscellaneous: Present with 784 molecules/cell in log phase SD medium.

Sequence similarities: To K.lactis GAL80.
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 Research Articles on GAL80    1. Overproduction of Gal3p or Gal4p mutants with altered Gal80p-binding characteristics restores GAL gene expression in mutants deficient in ATP or NADP(H) synthesis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GAL80 peptide
 Reference Product  PubMed Publications
 GAL4 peptide  >148 publications with GAL80 and GAL4
 GAL1 peptide  >49 publications with GAL80 and GAL1
 GAL3 peptide  >46 publications with GAL80 and GAL3
 GAL7 peptide  >19 publications with GAL80 and GAL7
 GAL2 peptide  >7 publications with GAL80 and GAL2
 SNF1 peptide  >2 publications with GAL80 and SNF1
 MDM30 peptide  >2 publications with GAL80 and MDM30
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