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HSD3B1 peptide

Scan QR to view Datasheet Catalog #    MBS425353 HSD3B1 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

HSD3B1, Peptide

 Also Known As   

HSD3B1 Immunizing Peptide

 Product Synonym Names    HSD3B1; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; HGNC: 5217; HSD3B; HSDB3; Hydroxy-delta-5-steroid dehydrogenase; 3 beta- and steroid hydroxy-delta-5-steroid dehydrogenase; 3 beta-and steroid delta-isomerase 1
 Product Gene Name   

HSD3B1 peptide

[Similar Products]
 Antibody/Peptide Pairs    HSD3B1 peptide (MBS425353) is used for blocking the activity of HSD3B1 antibody (MBS420114)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-DRHKETLK SKTQ
 OMIM    109715
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of HSD3B1 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for HSD3B1. It may not necessarily be applicable to this product.
 NCBI GI #    4504507
 NCBI GeneID    3283
 NCBI Accession #    NP_000853.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000862.2 [Other Products]
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 UniProt Secondary Accession #    Q14545; Q8IV65; A8K691 [Other Products]
 UniProt Related Accession #    P14060 [Other Products]
 Molecular Weight    42,252 Da
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 NCBI Official Full Name    3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
 NCBI Official Synonym Full Names    hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
 NCBI Official Symbol    HSD3B1 [Similar Products]
 NCBI Official Synonym Symbols   
I; HSD3B; HSDB3; HSDB3A; SDR11E1; 3BETAHSD
[Similar Products]
 NCBI Protein Information    3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
 UniProt Protein Name    3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
 UniProt Synonym Protein Names   
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3-beta-HSD I; Trophoblast antigen FDO161GIncluding the following 2 domains:3-beta-hydroxy-Delta(5)-steroid dehydrogenase (EC:1.1.1.145)Alternative name(s):3-beta-hydroxy-5-ene steroid dehydrogenase; Progesterone reductase
 Protein Family    3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
 UniProt Gene Name    HSD3B1 [Similar Products]
 UniProt Synonym Gene Names    3BH; HSDB3A; 3-beta-HSD I [Similar Products]
 UniProt Entry Name    3BHS1_HUMAN
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 UniProt Comments for HSD3B1    HSD3B1: 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17- alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosterone. Belongs to the 3-beta-HSD family.

Protein type: Lipid Metabolism - androgen and estrogen; Isomerase; Membrane protein, integral; EC 5.3.3.1; Oxidoreductase; Mitochondrial; Lipid Metabolism - C21-steroid hormone; EC 1.1.1.145

Chromosomal Location of Human Ortholog: 1p13.1

Cellular Component: endoplasmic reticulum membrane; integral to membrane; mitochondrial inner membrane; mitochondrial intermembrane space; smooth endoplasmic reticulum membrane

Molecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity; steroid delta-isomerase activity

Biological Process: androgen biosynthetic process; estrogen biosynthetic process; glucocorticoid biosynthetic process; mineralocorticoid biosynthetic process; steroid biosynthetic process
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 Research Articles on HSD3B1    1. HSD3B1 is involved in aldosterone production, despite its lower levels of expression compared with HSD3B2, and also possibly associated with KCNJ5 mutation in aldosterone-producing adenoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with HSD3B1 peptideDiseases associated with HSD3B1 peptide
 Products by Pathway  Pathway Diagram
 Aldosterone Synthesis And Secretion Pathway antibodies  Aldosterone Synthesis And Secretion Pathway Diagram
 Aldosterone Synthesis And Secretion Pathway antibodies  Aldosterone Synthesis And Secretion Pathway Diagram
 Androgen Biosynthesis Pathway antibodies  Androgen Biosynthesis Pathway Diagram
 C19/C18-Steroid Hormone Biosynthesis, Pregnenolone => Androstenedione => Estrone Pathway antibodies  C19/C18-Steroid Hormone Biosynthesis, Pregnenolone => Androstenedione => Estrone Pathway Diagram
 C19/C18-Steroid Hormone Biosynthesis, Pregnenolone => Androstenedione => Estrone Pathway antibodies  C19/C18-Steroid Hormone Biosynthesis, Pregnenolone => Androstenedione => Estrone Pathway Diagram
 Corticotropin-releasing Hormone Pathway antibodies  Corticotropin-releasing Hormone Pathway Diagram
 Glucocorticoid & Mineralcorticoid Metabolism Pathway antibodies  Glucocorticoid & Mineralcorticoid Metabolism Pathway Diagram
 Glucocorticoid Biosynthesis Pathway antibodies  Glucocorticoid Biosynthesis Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Disease Name  Pubmed Publications
 Genital Diseases, Male Antibodies  >19 publications with HSD3B1 and Genital Diseases, Male
 Hyperplasia Antibodies  >15 publications with HSD3B1 and Hyperplasia
 Hypertension Antibodies  >13 publications with HSD3B1 and Hypertension
 Prostatic Neoplasms Antibodies  >13 publications with HSD3B1 and Prostatic Neoplasms
 Cardiovascular Diseases Antibodies  >11 publications with HSD3B1 and Cardiovascular Diseases
 Congenital Abnormalities Antibodies  >9 publications with HSD3B1 and Congenital Abnormalities
 Breast Neoplasms Antibodies  >8 publications with HSD3B1 and Breast Neoplasms
 Necrosis Antibodies  >6 publications with HSD3B1 and Necrosis
 Hypertrophy Antibodies  >3 publications with HSD3B1 and Hypertrophy
 Infertility, Male Antibodies  >3 publications with HSD3B1 and Infertility, Male
Organs/Tissues associated with HSD3B1 peptide
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >44 publications with HSD3B1 and Testis
 Blood Antibodies  >38 publications with HSD3B1 and Blood
 Placenta Antibodies  >23 publications with HSD3B1 and Placenta
 Embryonic Tissue Antibodies  >11 publications with HSD3B1 and Embryonic Tissue
 Uterus Antibodies  >8 publications with HSD3B1 and Uterus
 Heart Antibodies  >5 publications with HSD3B1 and Heart
 Skin Antibodies  >3 publications with HSD3B1 and Skin
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