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HRH1 peptide :: Histamine receptor H1 Peptide

Scan QR to view Datasheet Catalog #    MBS425852 HRH1 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Histamine receptor H1 (HRH1), Peptide

 Also Known As   

Histamine receptor H1 Immunizing Peptide

 Product Synonym Names    histamine receptor H1; H1-R; HRH1; hisH1; histamine receptor, subclass H1; Histamine receptor H1; Histamine receptor H1(internal)
 Product Gene Name   

HRH1 peptide

[Similar Products]
 Antibody/Peptide Pairs    Histamine receptor H1 peptide (MBS425852) is used for blocking the activity of Histamine receptor H1 antibody (MBS421215)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    QQTSVRREDK CETD
 OMIM    600167
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of HRH1 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for HRH1. It may not necessarily be applicable to this product.
 NCBI GI #    4504491
 NCBI GeneID    3269
 NCBI Accession #    NP_000852.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000861.3 [Other Products]
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 UniProt Secondary Accession #    Q6P9E5; A8K047 [Other Products]
 UniProt Related Accession #    P35367 [Other Products]
 Molecular Weight    55,784 Da
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 NCBI Official Full Name    histamine H1 receptor
 NCBI Official Synonym Full Names    histamine receptor H1
 NCBI Official Symbol    HRH1 [Similar Products]
 NCBI Official Synonym Symbols   
H1R; H1-R; HH1R; hisH1
[Similar Products]
 NCBI Protein Information    histamine H1 receptor
 UniProt Protein Name    Histamine H1 receptor
 Protein Family    Histamine H1 receptor
 UniProt Gene Name    HRH1 [Similar Products]
 UniProt Synonym Gene Names    H1R; HH1R [Similar Products]
 UniProt Entry Name    HRH1_HUMAN
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 NCBI Summary for HRH1    Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2015]
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 UniProt Comments for HRH1    H1R: In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 3p25

Cellular Component: cytoplasm; integral to plasma membrane; nucleoplasm; plasma membrane

Molecular Function: G-protein coupled receptor activity; histamine receptor activity

Biological Process: eosinophil chemotaxis; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); inflammatory response; inositol phosphate-mediated signaling; memory; positive regulation of inositol trisphosphate biosynthetic process; positive regulation of vasoconstriction; regulation of synaptic plasticity; regulation of synaptic transmission; regulation of vascular permeability; regulation of vasoconstriction; visual learning
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 Research Articles on HRH1    1. HRH1-17 TT and HNMT-1639 TT genotypes were associated with the allergic asthma phenotype among African-American children and that the ABP 4107 GG genotype was associated with nonallergic asthma among white children.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HRH1 peptidePathways associated with HRH1 peptide
 Reference Product  PubMed Publications
 HCRTR1 peptide  >1 publications with HRH1 and HCRTR1
 HCRT peptide  >1 publications with HRH1 and HCRT
 Products by Pathway  Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Histamine Receptors Pathway antibodies  Histamine Receptors Pathway Diagram
Diseases associated with HRH1 peptideOrgans/Tissues associated with HRH1 peptide
 Disease Name  Pubmed Publications
 Hypersensitivity Antibodies  >9 publications with HRH1 and Hypersensitivity
 Nervous System Diseases Antibodies  >7 publications with HRH1 and Nervous System Diseases
 Inflammation Antibodies  >5 publications with HRH1 and Inflammation
 Respiratory Hypersensitivity Antibodies  >4 publications with HRH1 and Respiratory Hypersensitivity
 Pain Antibodies  >4 publications with HRH1 and Pain
 Drug-Related Side Effects and Adverse Reactions Antibodies  >2 publications with HRH1 and Drug-Related Side Effects and Adverse Reactions
 Urticaria Antibodies  >2 publications with HRH1 and Urticaria
 Seizures Antibodies  >2 publications with HRH1 and Seizures
 Bipolar Disorder Antibodies  >2 publications with HRH1 and Bipolar Disorder
 Weight Loss Antibodies  >1 publications with HRH1 and Weight Loss
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with HRH1 and Brain
 Vascular Antibodies  >5 publications with HRH1 and Vascular
 Skin Antibodies  >4 publications with HRH1 and Skin
 Lung Antibodies  >3 publications with HRH1 and Lung
 Liver Antibodies  >3 publications with HRH1 and Liver
 Kidney Antibodies  >3 publications with HRH1 and Kidney
 Testis Antibodies  >3 publications with HRH1 and Testis
 Adrenal Gland Antibodies  >2 publications with HRH1 and Adrenal Gland
 Thymus Antibodies  >1 publications with HRH1 and Thymus
 Connective Tissue Antibodies  >1 publications with HRH1 and Connective Tissue
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