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IFNAR2 peptide

Scan QR to view Datasheet Catalog #    MBS425918 IFNAR2 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IFNAR2, Peptide

 Also Known As   

IFNAR2 Immunizing Peptide

 Product Synonym Names    IFNAR2; interferon (alpha, beta and omega) receptor 2; IFN-R; IFN-alpha-REC; IFNABR; IFNARB
 Product Gene Name   

IFNAR2 peptide

[Similar Products]
 Antibody/Peptide Pairs    IFNAR2 peptide (MBS425918) is used for blocking the activity of IFNAR2 antibody (MBS421882)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    SYDSPDYTDE SCT
 OMIM    602376
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of IFNAR2 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for IFNAR2. It may not necessarily be applicable to this product.
 NCBI GI #    19923129
 NCBI GeneID    3455
 NCBI Accession #    NP_000865.2 [Other Products]
 NCBI Related Accession #    NP_997467.1; NP_997468.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000874.4 [Other Products]
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 UniProt Secondary Accession #    Q15467; Q6FHD7; A8KAJ4; D3DSE8; D3DSE9 [Other Products]
 UniProt Related Accession #    P48551 [Other Products]
 Molecular Weight    27,384 Da
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 NCBI Official Full Name    interferon alpha/beta receptor 2 isoform b
 NCBI Official Synonym Full Names    interferon alpha and beta receptor subunit 2
 NCBI Official Symbol    IFNAR2 [Similar Products]
 NCBI Official Synonym Symbols   
IFN-R; IMD45; IFNABR; IFNARB; IFN-alpha-REC
[Similar Products]
 NCBI Protein Information    interferon alpha/beta receptor 2
 UniProt Protein Name    Interferon alpha/beta receptor 2
 UniProt Synonym Protein Names   
Interferon alpha binding protein; Type I interferon receptor 2
 Protein Family    Interferon alpha/beta receptor
 UniProt Gene Name    IFNAR2 [Similar Products]
 UniProt Synonym Gene Names    IFNABR; IFNARB; IFN-R-2; IFN-alpha binding protein; IFN-alpha/beta receptor 2 [Similar Products]
 UniProt Entry Name    INAR2_HUMAN
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 NCBI Summary for IFNAR2    The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IFNAR2    IFNAR2: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity. Belongs to the type II cytokine receptor family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 21q22.11

Cellular Component: extracellular region; extracellular space; integral to plasma membrane; intracellular; plasma membrane

Molecular Function: interferon-alpha/beta binding; interferon-alpha/beta receptor activity; interleukin-20 binding; protein binding; protein kinase binding

Biological Process: cell proliferation; cell surface receptor linked signal transduction; JAK-STAT cascade; regulation of transcription from RNA polymerase II promoter; response to virus

Disease: Hepatitis B Virus, Susceptibility To
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 Research Articles on IFNAR2    1. The expression of IFNAR1, IFNgammaR1 and ribovarin transporters were significantly impaired in chronic liver disease and cirrhotic livers.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IFNAR2 peptidePathways associated with IFNAR2 peptide
 Reference Product  PubMed Publications
 IFNAR1 peptide  >183 publications with IFNAR2 and IFNAR1
 STAT1 peptide  >46 publications with IFNAR2 and STAT1
 STAT2 peptide  >35 publications with IFNAR2 and STAT2
 JAK1 peptide  >29 publications with IFNAR2 and JAK1
 TYK2 peptide  >26 publications with IFNAR2 and TYK2
 IFNA2 peptide  >4 publications with IFNAR2 and IFNA2
 GNB2L1 peptide  >2 publications with IFNAR2 and GNB2L1
 IFNB1 peptide  >1 publications with IFNAR2 and IFNB1
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Downstream Signaling In Naive CD8+ T Cells Pathway antibodies  Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
Diseases associated with IFNAR2 peptideOrgans/Tissues associated with IFNAR2 peptide
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >36 publications with IFNAR2 and Liver Diseases
 Carcinoma Antibodies  >28 publications with IFNAR2 and Carcinoma
 Nervous System Diseases Antibodies  >19 publications with IFNAR2 and Nervous System Diseases
 Adenocarcinoma Antibodies  >18 publications with IFNAR2 and Adenocarcinoma
 Carcinoma, Hepatocellular Antibodies  >17 publications with IFNAR2 and Carcinoma, Hepatocellular
 Necrosis Antibodies  >11 publications with IFNAR2 and Necrosis
 Inflammation Antibodies  >11 publications with IFNAR2 and Inflammation
 Liver Neoplasms Antibodies  >10 publications with IFNAR2 and Liver Neoplasms
 Hepatitis B Antibodies  >8 publications with IFNAR2 and Hepatitis B
 Cardiovascular Diseases Antibodies  >7 publications with IFNAR2 and Cardiovascular Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >57 publications with IFNAR2 and Blood
 Liver Antibodies  >37 publications with IFNAR2 and Liver
 Lung Antibodies  >13 publications with IFNAR2 and Lung
 Kidney Antibodies  >8 publications with IFNAR2 and Kidney
 Bone Marrow Antibodies  >7 publications with IFNAR2 and Bone Marrow
 Uterus Antibodies  >7 publications with IFNAR2 and Uterus
 Spleen Antibodies  >7 publications with IFNAR2 and Spleen
 Brain Antibodies  >7 publications with IFNAR2 and Brain
 Lymph Node Antibodies  >3 publications with IFNAR2 and Lymph Node
 Pancreas Antibodies  >3 publications with IFNAR2 and Pancreas
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