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DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

IGFBP4 peptide

Scan QR to view Datasheet Catalog #    MBS426499 IGFBP4 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IGFBP4, Peptide

 Also Known As   

IGFBP4 Immunizing Peptide

 Product Synonym Names    IGFBP4; insulin-like growth factor binding protein 4; BP-4; HT29-IGFBP; IBP4; IGFBP-4; IGF-binding protein 4; insulin-like growth factor-binding protein 4
 Product Gene Name   

IGFBP4 peptide

[Similar Products]
 Antibody/Peptide Pairs    IGFBP4 peptide (MBS426499) is used for blocking the activity of IGFBP4 antibody (MBS420440)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    KGELDCHQLA DSFRE
 OMIM    146733
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 Species Reactivity    Human, Mouse, Cow
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of IGFBP4 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for IGFBP4. It may not necessarily be applicable to this product.
 NCBI GI #    62243290
 NCBI GeneID    3487
 NCBI Accession #    NP_001543.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001552.2 [Other Products]
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 UniProt Secondary Accession #    Q5U012; Q9UCL6; A0N9W2; B4E351 [Other Products]
 UniProt Related Accession #    P22692 [Other Products]
 Molecular Weight    17,635 Da
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 NCBI Official Full Name    insulin-like growth factor-binding protein 4
 NCBI Official Synonym Full Names    insulin like growth factor binding protein 4
 NCBI Official Symbol    IGFBP4 [Similar Products]
 NCBI Official Synonym Symbols   
BP-4; IBP4; IGFBP-4; HT29-IGFBP
[Similar Products]
 NCBI Protein Information    insulin-like growth factor-binding protein 4
 UniProt Protein Name    Insulin-like growth factor-binding protein 4
 Protein Family    Insulin-like growth factor-binding protein
 UniProt Gene Name    IGFBP4 [Similar Products]
 UniProt Synonym Gene Names    IBP4; IBP-4; IGF-binding protein 4; IGFBP-4 [Similar Products]
 UniProt Entry Name    IBP4_HUMAN
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 NCBI Summary for IGFBP4    This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IGFBP4    IGFBP4: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: extracellular region; extracellular space

Molecular Function: insulin-like growth factor I binding; insulin-like growth factor II binding; receptor binding

Biological Process: cell proliferation; cellular protein metabolic process; DNA metabolic process; inflammatory response; positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of MAPKKK cascade; regulation of cell growth; regulation of insulin-like growth factor receptor signaling pathway; signal transduction; skeletal development
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 Research Articles on IGFBP4    1. The present study provides the first evidence that apoptosis inhibitor of macrophages binds to IGFBP2, 3 and 4.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with IGFBP4 peptideDiseases associated with IGFBP4 peptide
 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies  Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram
 Wnt Signaling Network Pathway antibodies  Wnt Signaling Network Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >34 publications with IGFBP4 and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >29 publications with IGFBP4 and Breast Neoplasms
 Hypertrophy Antibodies  >26 publications with IGFBP4 and Hypertrophy
 Kidney Diseases Antibodies  >23 publications with IGFBP4 and Kidney Diseases
 Inflammation Antibodies  >22 publications with IGFBP4 and Inflammation
 Nervous System Diseases Antibodies  >21 publications with IGFBP4 and Nervous System Diseases
 Adenocarcinoma Antibodies  >21 publications with IGFBP4 and Adenocarcinoma
 Necrosis Antibodies  >21 publications with IGFBP4 and Necrosis
 Weight Loss Antibodies  >15 publications with IGFBP4 and Weight Loss
 Prostatic Neoplasms Antibodies  >14 publications with IGFBP4 and Prostatic Neoplasms
Organs/Tissues associated with IGFBP4 peptide
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >208 publications with IGFBP4 and Blood
 Bone Antibodies  >112 publications with IGFBP4 and Bone
 Muscle Antibodies  >109 publications with IGFBP4 and Muscle
 Ovary Antibodies  >106 publications with IGFBP4 and Ovary
 Liver Antibodies  >77 publications with IGFBP4 and Liver
 Vascular Antibodies  >67 publications with IGFBP4 and Vascular
 Connective Tissue Antibodies  >55 publications with IGFBP4 and Connective Tissue
 Kidney Antibodies  >55 publications with IGFBP4 and Kidney
 Brain Antibodies  >41 publications with IGFBP4 and Brain
 Embryonic Tissue Antibodies  >33 publications with IGFBP4 and Embryonic Tissue
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