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IGF2BP1 peptide :: IMP1 / ZBP1 Peptide

Scan QR to view Datasheet Catalog #    MBS427271 IGF2BP1 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IMP1 / ZBP1 (IGF2BP1), Peptide

 Also Known As   

IMP1 / ZBP1 Immunizing Peptide

 Product Synonym Names    IGF2BP1; insulin-like growth factor 2 mRNA binding protein 1; CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1; IGF II mRNA binding protein 1; IGF2 mRNA-binding protein 1; VICKZ family member 1; coding region determinant-binding protein; zipcode-binding protein 1; IMP1 / ZBP1
 Product Gene Name   

IGF2BP1 peptide

[Similar Products]
 Product Synonym Gene Name    IMP1; ZBP1 [Similar Products]
 Antibody/Peptide Pairs    IMP1 / ZBP1 peptide (MBS427271) is used for blocking the activity of IMP1/ZBP1 antibody (MBS422379)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-EKVFAEHK ISYSGQ
 OMIM    608288
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 Species Reactivity    Human, Mouse, Rat, Dog, Cow
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of IGF2BP1 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for IGF2BP1. It may not necessarily be applicable to this product.
 NCBI GI #    56237027
 NCBI GeneID    10642
 NCBI Accession #    NP_006537.3 [Other Products]
 NCBI Related Accession #    NP_001153895.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006546.3 [Other Products]
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 UniProt Secondary Accession #    C9JT33 [Other Products]
 UniProt Related Accession #    Q9NZI8 [Other Products]
 Molecular Weight    48,598 Da
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 NCBI Official Full Name    insulin-like growth factor 2 mRNA-binding protein 1 isoform 1
 NCBI Official Synonym Full Names    insulin like growth factor 2 mRNA binding protein 1
 NCBI Official Symbol    IGF2BP1 [Similar Products]
 NCBI Official Synonym Symbols   
IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1
[Similar Products]
 NCBI Protein Information    insulin-like growth factor 2 mRNA-binding protein 1
 UniProt Protein Name    Insulin-like growth factor 2 mRNA-binding protein 1
 UniProt Synonym Protein Names   
Coding region determinant-binding protein; CRD-BP; IGF-II mRNA-binding protein 1; VICKZ family member 1; Zipcode-binding protein 1; ZBP-1
 Protein Family    Insulin-like growth factor 2 mRNA-binding protein
 UniProt Gene Name    IGF2BP1 [Similar Products]
 UniProt Synonym Gene Names    CRDBP; VICKZ1; ZBP1; IGF2 mRNA-binding protein 1; IMP-1; IMP1; CRD-BP; ZBP-1 [Similar Products]
 UniProt Entry Name    IF2B1_HUMAN
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 NCBI Summary for IGF2BP1    This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
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 UniProt Comments for IGF2BP1    IGF2BP1: a conserved trans-acting factor that can control translation of specific mRNAs in vivo. Contains four K homology (KH) domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the target mRNAs and repressing translation. Target mRNAs include those encoding beta-actin and insulin-like growth factor 2 (IGF2). Tyrosine phosphorylation apparently abolishes translational repression of actin expression by decreasing its binding beta-actin mRNA. May have a role in progression of ovarian cancer. Contains nuclear export signals within the RNA-binding KH2 and KH4 domains. Aberrant expression may interfere with c-myc regulation.

Protein type: Translation; RNA-binding

Chromosomal Location of Human Ortholog: 17q21.32

Cellular Component: axon; cytoplasm; cytosol; dendritic spine; filopodium; growth cone; lamellipodium; nucleus; perinuclear region of cytoplasm; ribonucleoprotein complex; stress granule

Molecular Function: mRNA 3'-UTR binding; mRNA 5'-UTR binding; mRNA binding; nucleotide binding; protein binding; translation regulator activity

Biological Process: gene expression; mRNA transport; negative regulation of translation; pallium cell proliferation in the forebrain; regulation of cytokine biosynthetic process
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 Research Articles on IGF2BP1    1. IGF2BP1 as a direct and functional target of miR-196b.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IGF2BP1 peptidePathways associated with IGF2BP1 peptide
 Reference Product  PubMed Publications
 IGF2 peptide  >16 publications with IGF2BP1 and IGF2
 MYC peptide  >10 publications with IGF2BP1 and MYC
 PTEN peptide  >5 publications with IGF2BP1 and PTEN
 DHX9 peptide  >3 publications with IGF2BP1 and DHX9
 CTNNB1 peptide  >3 publications with IGF2BP1 and CTNNB1
 LIN28A peptide  >2 publications with IGF2BP1 and LIN28A
 YBX1 peptide  >2 publications with IGF2BP1 and YBX1
 HNRNPU peptide  >1 publications with IGF2BP1 and HNRNPU
 SYNCRIP peptide  >1 publications with IGF2BP1 and SYNCRIP
 Products by Pathway  Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Insulin-like Growth Factor-2 MRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) Bind RNA Pathway antibodies  Insulin-like Growth Factor-2 MRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) Bind RNA Pathway Diagram
 MAPK Family Signaling Cascades Pathway antibodies  MAPK Family Signaling Cascades Pathway Diagram
 MAPK6/MAPK4 Signaling Pathway antibodies  MAPK6/MAPK4 Signaling Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway antibodies  Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
Diseases associated with IGF2BP1 peptideOrgans/Tissues associated with IGF2BP1 peptide
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >8 publications with IGF2BP1 and Carcinoma
 Liver Diseases Antibodies  >6 publications with IGF2BP1 and Liver Diseases
 Neoplasm Metastasis Antibodies  >4 publications with IGF2BP1 and Neoplasm Metastasis
 Insulin Resistance Antibodies  >2 publications with IGF2BP1 and Insulin Resistance
 Infertility, Female Antibodies  >1 publications with IGF2BP1 and Infertility, Female
 Disease Models, Animal Antibodies  >1 publications with IGF2BP1 and Disease Models, Animal
 Kidney Diseases Antibodies  >1 publications with IGF2BP1 and Kidney Diseases
 Gonadal Disorders Antibodies  >1 publications with IGF2BP1 and Gonadal Disorders
 Neoplasms, Experimental Antibodies  >1 publications with IGF2BP1 and Neoplasms, Experimental
 Ovarian Diseases Antibodies  >1 publications with IGF2BP1 and Ovarian Diseases
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >6 publications with IGF2BP1 and Liver
 Blood Antibodies  >6 publications with IGF2BP1 and Blood
 Brain Antibodies  >5 publications with IGF2BP1 and Brain
 Bone Antibodies  >5 publications with IGF2BP1 and Bone
 Lymph Node Antibodies  >3 publications with IGF2BP1 and Lymph Node
 Muscle Antibodies  >3 publications with IGF2BP1 and Muscle
 Lymph Antibodies  >3 publications with IGF2BP1 and Lymph
 Embryonic Tissue Antibodies  >3 publications with IGF2BP1 and Embryonic Tissue
 Heart Antibodies  >2 publications with IGF2BP1 and Heart
 Kidney Antibodies  >1 publications with IGF2BP1 and Kidney
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