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KLK5 peptide

Scan QR to view Datasheet Catalog #    MBS426837 KLK5 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

KLK5, Peptide

 Also Known As   

KLK5 Immunizing Peptide

 Product Synonym Names    KLK5; kallikrein-related peptidase 5; KLK-L2; KLKL2; SCTE; kallikrein 5; kallikrein-like protein 2; stratum corneum tryptic enzyme
 Product Gene Name   

KLK5 peptide

[Similar Products]
 Antibody/Peptide Pairs    KLK5 peptide (MBS426837) is used for blocking the activity of KLK5 antibody (MBS420050)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    KAGRDSCQGD
 OMIM    605643
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 Species Reactivity    Human, Rat, Dog, Cow
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of KLK5 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for KLK5. It may not necessarily be applicable to this product.
 NCBI GI #    6912644
 NCBI GeneID    25818
 NCBI Accession #    NP_036559.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012427.4 [Other Products]
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 UniProt Secondary Accession #    Q53ZR3; Q9HBG8 [Other Products]
 UniProt Related Accession #    Q9Y337 [Other Products]
 Molecular Weight    32,019 Da
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 NCBI Official Full Name    kallikrein-5 preproprotein
 NCBI Official Synonym Full Names    kallikrein related peptidase 5
 NCBI Official Symbol    KLK5 [Similar Products]
 NCBI Official Synonym Symbols   
SCTE; KLKL2; KLK-L2
[Similar Products]
 NCBI Protein Information    kallikrein-5
 UniProt Protein Name    Kallikrein-5
 UniProt Synonym Protein Names   
Kallikrein-like protein 2; KLK-L2; Stratum corneum tryptic enzyme
 Protein Family    Kallikrein
 UniProt Gene Name    KLK5 [Similar Products]
 UniProt Synonym Gene Names    SCTE; KLK-L2 [Similar Products]
 UniProt Entry Name    KLK5_HUMAN
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 NCBI Summary for KLK5    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
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 UniProt Comments for KLK5    KLK5: May be involved in desquamation. Belongs to the peptidase S1 family. Kallikrein subfamily.

Protein type: EC 3.4.21.-; Secreted, signal peptide; Protease; Secreted

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: extracellular space

Molecular Function: peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: epidermis development; positive regulation of antibacterial peptide production; positive regulation of G-protein coupled receptor protein signaling pathway; proteolysis
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 Research Articles on KLK5    1. This report demonstrates that concurrent loss of KLK5 and KLK7 associates with a poor clinical outcome in Oral Squamous-Cell Carcinoma and could therefore serve as prognostic marker in this disease.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with KLK5 peptideDiseases associated with KLK5 peptide
 Reference Product  PubMed Publications
 SPINK5 peptide  >26 publications with KLK5 and SPINK5
 DSG1 peptide  >8 publications with KLK5 and DSG1
 SPINK9 peptide  >6 publications with KLK5 and SPINK9
 DSC1 peptide  >5 publications with KLK5 and DSC1
 SPINK6 peptide  >4 publications with KLK5 and SPINK6
 FLG peptide  >4 publications with KLK5 and FLG
 CAMP peptide  >1 publications with KLK5 and CAMP
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >27 publications with KLK5 and Inflammation
 Dermatitis Antibodies  >25 publications with KLK5 and Dermatitis
 Ovarian Neoplasms Antibodies  >22 publications with KLK5 and Ovarian Neoplasms
 Breast Neoplasms Antibodies  >21 publications with KLK5 and Breast Neoplasms
 Prostatic Neoplasms Antibodies  >10 publications with KLK5 and Prostatic Neoplasms
 Carcinoma, Squamous Cell Antibodies  >7 publications with KLK5 and Carcinoma, Squamous Cell
 Disease Models, Animal Antibodies  >7 publications with KLK5 and Disease Models, Animal
 Lung Neoplasms Antibodies  >6 publications with KLK5 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >5 publications with KLK5 and Neoplasms, Experimental
 Necrosis Antibodies  >4 publications with KLK5 and Necrosis
Organs/Tissues associated with KLK5 peptide
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >96 publications with KLK5 and Skin
 Lung Antibodies  >6 publications with KLK5 and Lung
 Mammary Gland Antibodies  >6 publications with KLK5 and Mammary Gland
 Kidney Antibodies  >5 publications with KLK5 and Kidney
 Ovary Antibodies  >5 publications with KLK5 and Ovary
 Testis Antibodies  >4 publications with KLK5 and Testis
 Mouth Antibodies  >4 publications with KLK5 and Mouth
 Cervix Antibodies  >3 publications with KLK5 and Cervix
 Lymph Node Antibodies  >3 publications with KLK5 and Lymph Node
 Uncharacterized Tissue Antibodies  >2 publications with KLK5 and Uncharacterized Tissue
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