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LAMA5 peptide

Scan QR to view Datasheet Catalog #    MBS427609 LAMA5 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LAMA5, Peptide

 Also Known As   

LAMA5 Immunizing Peptide

 Product Synonym Names    LAMA5; laminin, alpha 5; KIAA1907; laminin alpha-5 chain; laminin subunit alpha-5; laminin-10 subunit alpha; laminin-11 subunit alpha; laminin-15 subunit alpha; LAMA5 (aa1029-1043)
 Product Gene Name   

LAMA5 peptide

[Similar Products]
 Antibody/Peptide Pairs    LAMA5 peptide (MBS427609) is used for blocking the activity of LAMA5 antibody (MBS422546)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    EACTYRPSAQ QSGDN
 OMIM    601033
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of LAMA5 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for LAMA5. It may not necessarily be applicable to this product.
 NCBI GI #    21264602
 NCBI GeneID    3911
 NCBI Accession #    NP_005551.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_005560.4 [Other Products]
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 UniProt Secondary Accession #    Q5U4N9; Q8TDF8; Q8WZA7; Q9H1P1 [Other Products]
 UniProt Related Accession #    O15230 [Other Products]
 Molecular Weight    61,287 Da
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 NCBI Official Full Name    laminin subunit alpha-5
 NCBI Official Synonym Full Names    laminin subunit alpha 5
 NCBI Official Symbol    LAMA5 [Similar Products]
 NCBI Protein Information    laminin subunit alpha-5
 UniProt Protein Name    Laminin subunit alpha-5
 UniProt Synonym Protein Names   
Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha
 Protein Family    Laminin
 UniProt Gene Name    LAMA5 [Similar Products]
 UniProt Synonym Gene Names    KIAA0533; KIAA1907 [Similar Products]
 UniProt Entry Name    LAMA5_HUMAN
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 NCBI Summary for LAMA5    This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013]
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 UniProt Comments for LAMA5    LAMA5: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Extracellular matrix; Secreted

Chromosomal Location of Human Ortholog: 20q13.2-q13.3

Cellular Component: basal lamina; basement membrane; extracellular matrix; extracellular region; extracellular space; laminin-10 complex; laminin-5 complex; nucleus

Molecular Function: integrin binding; structural molecule activity

Biological Process: angiogenesis; cell differentiation; cell migration; cell proliferation; cell recognition; cilium biogenesis; cytoskeleton organization and biogenesis; embryonic development; endothelial cell differentiation; extracellular matrix organization and biogenesis; focal adhesion formation; hair follicle development; integrin-mediated signaling pathway; lung development; morphogenesis of a polarized epithelium; morphogenesis of embryonic epithelium; muscle development; neural crest cell migration; odontogenesis of dentine-containing teeth; regulation of cell adhesion; regulation of cell migration; regulation of cell proliferation; regulation of embryonic development; ureteric bud branching
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 Research Articles on LAMA5    1. disruption of the LAMA5 gene dramatically reduced hPSC self-renewal and increased apoptosis without affecting the expression of pluripotency markers.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with LAMA5 peptideDiseases associated with LAMA5 peptide
 Products by Pathway  Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 ECM Proteoglycans Pathway antibodies  ECM Proteoglycans Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >5 publications with LAMA5 and Kidney Diseases
 Congenital Abnormalities Antibodies  >4 publications with LAMA5 and Congenital Abnormalities
 Disease Models, Animal Antibodies  >3 publications with LAMA5 and Disease Models, Animal
 Carcinoma Antibodies  >3 publications with LAMA5 and Carcinoma
 Breast Neoplasms Antibodies  >2 publications with LAMA5 and Breast Neoplasms
 Lung Diseases Antibodies  >2 publications with LAMA5 and Lung Diseases
 Inflammation Antibodies  >2 publications with LAMA5 and Inflammation
 Fibrosis Antibodies  >1 publications with LAMA5 and Fibrosis
 Cardiovascular Diseases Antibodies  >1 publications with LAMA5 and Cardiovascular Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with LAMA5 and Cell Transformation, Neoplastic
Organs/Tissues associated with LAMA5 peptide
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >10 publications with LAMA5 and Kidney
 Embryonic Tissue Antibodies  >10 publications with LAMA5 and Embryonic Tissue
 Lung Antibodies  >7 publications with LAMA5 and Lung
 Vascular Antibodies  >7 publications with LAMA5 and Vascular
 Skin Antibodies  >5 publications with LAMA5 and Skin
 Placenta Antibodies  >4 publications with LAMA5 and Placenta
 Liver Antibodies  >3 publications with LAMA5 and Liver
 Mouth Antibodies  >2 publications with LAMA5 and Mouth
 Heart Antibodies  >2 publications with LAMA5 and Heart
 Spleen Antibodies  >1 publications with LAMA5 and Spleen
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