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Lcn2 peptide :: Lipocalin 2 / NGAL Peptide

Scan QR to view Datasheet Catalog #    MBS425510 Lcn2 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Lipocalin 2 / NGAL (Lcn2), Peptide

 Also Known As   

Lipocalin 2 / NGAL Immunizing Peptide

 Product Synonym Names    Lcn2; lipocalin 2; NGAL; RP23-161B9.11; 24p3; AW212229; NGAL; Lipocalin 2; Lipocalin 2 / NGAL (mouse)
 Product Gene Name   

Lcn2 peptide

[Similar Products]
 Product Synonym Gene Name    NGAL [Similar Products]
 Antibody/Peptide Pairs    Lipocalin 2 / NGAL peptide (MBS425510) is used for blocking the activity of Lipocalin 2/NGAL antibody (MBS420046)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-HRYPQVQS YNVQ
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 Species Reactivity    Mouse
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of Lcn2 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Lcn2. It may not necessarily be applicable to this product.
 NCBI GI #    34328049
 NCBI GeneID    16819
 NCBI Accession #    NP_032517.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_008491.1 [Other Products]
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 UniProt Secondary Accession #    Q3UE34 [Other Products]
 UniProt Related Accession #    P11672 [Other Products]
 Molecular Weight    22,875 Da
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 NCBI Official Full Name    neutrophil gelatinase-associated lipocalin
 NCBI Official Synonym Full Names    lipocalin 2
 NCBI Official Symbol    Lcn2 [Similar Products]
 NCBI Official Synonym Symbols   
24p3; Sip24; AW212229
[Similar Products]
 NCBI Protein Information    neutrophil gelatinase-associated lipocalin
 UniProt Protein Name    Neutrophil gelatinase-associated lipocalin
 UniProt Synonym Protein Names   
Lipocalin-2; SV-40-induced 24P3 protein; Siderocalin LCN2; p25
 Protein Family    Neutrophil gelatinase-associated lipocalin
 UniProt Gene Name    Lcn2 [Similar Products]
 UniProt Synonym Gene Names    NGAL [Similar Products]
 UniProt Entry Name    NGAL_MOUSE
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 UniProt Comments for Lcn2    LCN2: Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5- DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth. Belongs to the calycin superfamily. Lipocalin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: cytosol; extracellular region; extracellular space

Molecular Function: iron ion binding; protease binding; protein binding; protein homodimerization activity; transporter activity

Biological Process: apoptosis; immune system process; innate immune response; ion transport; iron ion homeostasis; positive regulation of cell projection organization and biogenesis; response to drug; response to herbicide; response to virus; siderophore transport; transport
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 Research Articles on Lcn2    1. Our observations suggest that Lcn2 promotes host resistance to Salmonella Typhimurium infection
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Lcn2 peptidePathways associated with Lcn2 peptide
 Reference Product  PubMed Publications
 Mmp9 peptide  >39 publications with Lcn2 and Mmp9
 Hmox1 peptide  >19 publications with Lcn2 and Hmox1
 Erbb2 peptide  >10 publications with Lcn2 and Erbb2
 Mmp2 peptide  >8 publications with Lcn2 and Mmp2
 Tlr2 peptide  >4 publications with Lcn2 and Tlr2
 Il17a peptide  >3 publications with Lcn2 and Il17a
 Lep peptide  >1 publications with Lcn2 and Lep
 Il1r2 peptide  >1 publications with Lcn2 and Il1r2
 Lrp2 peptide  >1 publications with Lcn2 and Lrp2
 Products by Pathway  Pathway Diagram
 Iron Uptake And Transport Pathway antibodies  Iron Uptake And Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
Diseases associated with Lcn2 peptideOrgans/Tissues associated with Lcn2 peptide
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >789 publications with Lcn2 and Kidney Diseases
 Acute Kidney Injury Antibodies  >726 publications with Lcn2 and Acute Kidney Injury
 Renal Insufficiency Antibodies  >599 publications with Lcn2 and Renal Insufficiency
 Inflammation Antibodies  >361 publications with Lcn2 and Inflammation
 Cardiovascular Diseases Antibodies  >275 publications with Lcn2 and Cardiovascular Diseases
 Heart Diseases Antibodies  >147 publications with Lcn2 and Heart Diseases
 Necrosis Antibodies  >115 publications with Lcn2 and Necrosis
 Proteinuria Antibodies  >109 publications with Lcn2 and Proteinuria
 Disease Models, Animal Antibodies  >108 publications with Lcn2 and Disease Models, Animal
 Renal Insufficiency, Chronic Antibodies  >105 publications with Lcn2 and Renal Insufficiency, Chronic
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >989 publications with Lcn2 and Blood
 Kidney Antibodies  >909 publications with Lcn2 and Kidney
 Liver Antibodies  >185 publications with Lcn2 and Liver
 Brain Antibodies  >122 publications with Lcn2 and Brain
 Lung Antibodies  >94 publications with Lcn2 and Lung
 Adipose Tissue Antibodies  >46 publications with Lcn2 and Adipose Tissue
 Connective Tissue Antibodies  >42 publications with Lcn2 and Connective Tissue
 Bone Marrow Antibodies  >37 publications with Lcn2 and Bone Marrow
 Uterus Antibodies  >23 publications with Lcn2 and Uterus
 Embryonic Tissue Antibodies  >15 publications with Lcn2 and Embryonic Tissue
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