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MAX peptide

Scan QR to view Datasheet Catalog #    MBS425418 MAX peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MAX, Peptide

 Also Known As   

MAX Immunizing Peptide

 Product Synonym Names    MAX; MAX protein; MGC10775; MGC11225; MGC18164; MGC34679; MGC36767; myc-associated factor X; helix-loop-helix zipper protein; MYC associated factor X; bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; orf1
 Product Gene Name   

MAX peptide

[Similar Products]
 Antibody/Peptide Pairs    MAX peptide (MBS425418) is used for blocking the activity of MAX antibody (MBS421012)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-EEPQSRKK LRMEAS
 OMIM    154950
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 Species Reactivity    Human, Mouse, Rat, Dog, Cow
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of MAX peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for MAX. It may not necessarily be applicable to this product.
 NCBI GI #    21704261
 NCBI GeneID    4149
 NCBI Accession #    NP_002373.3 [Other Products]
 NCBI Related Accession #    NP_660087.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002382.4 [Other Products]
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 UniProt Secondary Accession #    P25912; P52163; Q14803; Q96CY8; A6NH73; A8K265; A8K4G4; A8K824 [Other Products]
 UniProt Related Accession #    P61244 [Other Products]
 Molecular Weight    9,599 Da
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 NCBI Official Full Name    protein max isoform a
 NCBI Official Synonym Full Names    MYC associated factor X
 NCBI Official Symbol    MAX [Similar Products]
 NCBI Official Synonym Symbols   
bHLHd4
[Similar Products]
 NCBI Protein Information    protein max
 UniProt Protein Name    Protein max
 UniProt Synonym Protein Names   
Class D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor X
 Protein Family    Maximin
 UniProt Gene Name    MAX [Similar Products]
 UniProt Synonym Gene Names    BHLHD4; bHLHd4 [Similar Products]
 UniProt Entry Name    MAX_HUMAN
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 NCBI Summary for MAX    The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
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 UniProt Comments for MAX    MAX: a transcription factor. Forms a DNA- binding protein complex with MYC or MAD. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. CPG methylation of the recognition site greatly inhibits DNA binding, suggesting that DNA methylation may regulate the MYC/MAX complex in vivo. May repress transcription via the recruitment of a chromatin remodeling complex containing H3-K9 histone methyltransferase activity. Three alternatively spliced isoforms have been reported.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 14q23

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: protein binding; transcription coactivator activity; transcription cofactor activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter
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 Research Articles on MAX    1. We confirmed that these dimeric inhibitors directly bind to Myc blocking its interaction with Max and affect transcription of MYC dependent genes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MAX peptidePathways associated with MAX peptide
 Reference Product  PubMed Publications
 MYC peptide  >1115 publications with MAX and MYC
 MYCN peptide  >632 publications with MAX and MYCN
 MXI1 peptide  >78 publications with MAX and MXI1
 MXD1 peptide  >73 publications with MAX and MXD1
 SMAD3 peptide  >20 publications with MAX and SMAD3
 SMAD4 peptide  >14 publications with MAX and SMAD4
 MAPK14 peptide  >10 publications with MAX and MAPK14
 EP300 peptide  >8 publications with MAX and EP300
 MXD3 peptide  >6 publications with MAX and MXD3
 MXD4 peptide  >6 publications with MAX and MXD4
 Products by Pathway  Pathway Diagram
 C-MYC Pathway antibodies  C-MYC Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cyclin A:Cdk2-associated Events At S Phase Entry Pathway antibodies  Cyclin A:Cdk2-associated Events At S Phase Entry Pathway Diagram
 Cyclin E Associated Events During G1/S Transition Pathway antibodies  Cyclin E Associated Events During G1/S Transition Pathway Diagram
 G1/S Transition Pathway antibodies  G1/S Transition Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
Diseases associated with MAX peptideOrgans/Tissues associated with MAX peptide
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >5577 publications with MAX and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >5531 publications with MAX and Nervous System Diseases
 Heart Diseases Antibodies  >3479 publications with MAX and Heart Diseases
 Immune System Diseases Antibodies  >2120 publications with MAX and Immune System Diseases
 Disease Models, Animal Antibodies  >1933 publications with MAX and Disease Models, Animal
 Inflammation Antibodies  >1534 publications with MAX and Inflammation
 Necrosis Antibodies  >1031 publications with MAX and Necrosis
 Diabetes Mellitus Antibodies  >966 publications with MAX and Diabetes Mellitus
 Liver Diseases Antibodies  >882 publications with MAX and Liver Diseases
 Kidney Diseases Antibodies  >744 publications with MAX and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >17307 publications with MAX and Blood
 Brain Antibodies  >12173 publications with MAX and Brain
 Heart Antibodies  >7910 publications with MAX and Heart
 Muscle Antibodies  >6358 publications with MAX and Muscle
 Vascular Antibodies  >4072 publications with MAX and Vascular
 Liver Antibodies  >3479 publications with MAX and Liver
 Nerve Antibodies  >3145 publications with MAX and Nerve
 Lung Antibodies  >2700 publications with MAX and Lung
 Eye Antibodies  >2519 publications with MAX and Eye
 Kidney Antibodies  >2402 publications with MAX and Kidney
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