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MBL2 peptide :: MBL2 / Mannan-Binding Lectin Peptide

Scan QR to view Datasheet Catalog #    MBS425407 MBL2 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MBL2 / Mannan-Binding Lectin, Peptide

 Also Known As   

MBL2 / Mannan-Binding Lectin Immunizing Peptide

 Product Synonym Names    MBL2; mannan-binding lectin; MBL; MBP; MBP1; COLEC1; HSMBPC; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannan-binding protein; mannose binding protein; Mannose-binding lectin 2, soluble (opsonic defect); MGC116832; MGC116833; mannose; Mannan-Binding Lectin; MBL2 / Mannan-Binding Lectin
 Product Gene Name   

MBL2 peptide

[Similar Products]
 Antibody/Peptide Pairs    MBL2 / Mannan-Binding Lectin peptide (MBS425407) is used for blocking the activity of MBL2/Mannan-Binding Lectin antibody (MBS420391)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    STSHLAVCEF PI
 OMIM    154545
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of MBL2 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for MBL2. It may not necessarily be applicable to this product.
 NCBI GI #    4557739
 NCBI GeneID    4153
 NCBI Accession #    NP_000233.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000242.2 [Other Products]
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 UniProt Secondary Accession #    Q4VB12; Q4VB13; Q4VB14; Q5SQS3; Q86SI4; Q96KE4; Q96TF7; Q96TF8; Q96TF9 [Other Products]
 UniProt Related Accession #    P11226 [Other Products]
 Molecular Weight    26,144 Da
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 NCBI Official Full Name    mannose-binding protein C
 NCBI Official Synonym Full Names    mannose binding lectin 2
 NCBI Official Symbol    MBL2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    mannose-binding protein C
 UniProt Protein Name    Mannose-binding protein C
 UniProt Synonym Protein Names   
Collectin-1; MBP1; Mannan-binding protein; Mannose-binding lectin
 Protein Family    Mannose-binding protein
 UniProt Gene Name    MBL2 [Similar Products]
 UniProt Synonym Gene Names    COLEC1; MBL; MBP-C [Similar Products]
 UniProt Entry Name    MBL2_HUMAN
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 NCBI Summary for MBL2    This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MBL2    MBL2: Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q11.2

Cellular Component: cell surface; collagen; extracellular region; extracellular space

Molecular Function: calcium ion binding; calcium-dependent protein binding; mannose binding; protein binding; receptor binding; serine-type endopeptidase activity

Biological Process: acute-phase response; complement activation; complement activation, classical pathway; complement activation, lectin pathway; defense response to bacterium; defense response to Gram-positive bacterium; innate immune response; killing by host of symbiont cells; negative regulation of viral reproduction; opsonization; positive regulation of phagocytosis; proteolysis; response to oxidative stress

Disease: Mannose-binding Protein Deficiency
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 Research Articles on MBL2    1. FCN2 and MBL2 allele frequencies were similarly distributed in early and late age-related macular degeneration cases compared with controls
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MBL2 peptidePathways associated with MBL2 peptide
 Reference Product  PubMed Publications
 MASP2 peptide  >42 publications with MBL2 and MASP2
 FCN2 peptide  >23 publications with MBL2 and FCN2
 MASP1 peptide  >9 publications with MBL2 and MASP1
 TLR3 peptide  >3 publications with MBL2 and TLR3
 LRP1 peptide  >1 publications with MBL2 and LRP1
 Products by Pathway  Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Creation Of C4 And C2 Activators Pathway antibodies  Creation Of C4 And C2 Activators Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Lectin Pathway Of Complement Activation antibodies  Lectin Pathway Of Complement Activation Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
Diseases associated with MBL2 peptideOrgans/Tissues associated with MBL2 peptide
 Disease Name  Pubmed Publications
 Infection Antibodies  >230 publications with MBL2 and Infection
 Inflammation Antibodies  >87 publications with MBL2 and Inflammation
 Liver Diseases Antibodies  >37 publications with MBL2 and Liver Diseases
 HIV Infections Antibodies  >29 publications with MBL2 and HIV Infections
 Fibrosis Antibodies  >27 publications with MBL2 and Fibrosis
 Hepatitis Antibodies  >24 publications with MBL2 and Hepatitis
 Heart Diseases Antibodies  >22 publications with MBL2 and Heart Diseases
 Necrosis Antibodies  >20 publications with MBL2 and Necrosis
 Disease Models, Animal Antibodies  >18 publications with MBL2 and Disease Models, Animal
 Kidney Diseases Antibodies  >14 publications with MBL2 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >53 publications with MBL2 and Liver
 Mixed Antibodies  >4 publications with MBL2 and Mixed
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