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MSLN peptide :: Mesothelin Peptide

Scan QR to view Datasheet Catalog #    MBS427195 MSLN peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Mesothelin (MSLN), Peptide

★Popular Item★
 Also Known As   

Mesothelin Immunizing Peptide

 Product Synonym Names    MSLN; mesothelin; CAK1; MPF; SMR; megakaryocyte potentiating factor; Mesothelin; Mesothelin
 Product Gene Name   

MSLN peptide

[Similar Products]
 Antibody/Peptide Pairs    Mesothelin peptide (MBS427195) is used for blocking the activity of Mesothelin antibody (MBS422284)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    CPSGKKAREI DES
 OMIM    601051
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 Form/Format    100ug of lyophilized peptide, formulation 5pmol,uL in 5% (v/v) acetonitrile /H20. Reconstitute in pellet in distilled water where required. For Blocking studies, reconstitute pellet in 200 uL distilled water to obtain a 0.5 mg/mL peptide solution.
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 Use    The peptide was used in the production of MBS427195- Goat Anti-Mesothelin Antibody. It is currently untested in blocking applications.
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 Preparation and Storage    Shipped at ambient temperature, store at -20C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of MSLN peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for MSLN. It may not necessarily be applicable to this product.
 NCBI GI #    53988378
 NCBI GeneID    10232
 NCBI Accession #    NP_005814.2 [Other Products]
 NCBI Related Accession #    NP_037536.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005823.5 [Other Products]
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 UniProt Secondary Accession #    Q14859; Q4VQD5; Q96GR6; Q96KJ5; Q9BR17; Q9BTR2; Q9UCB2; Q9UK57; D3DU65 [Other Products]
 UniProt Related Accession #    Q13421 [Other Products]
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 NCBI Official Full Name    mesothelin isoform 1 preproprotein
 NCBI Official Synonym Full Names    mesothelin
 NCBI Official Symbol    MSLN [Similar Products]
 NCBI Official Synonym Symbols   
MPF; SMRP
[Similar Products]
 NCBI Protein Information    mesothelin
 UniProt Protein Name    Mesothelin
 UniProt Synonym Protein Names   
CAK1 antigen; Pre-pro-megakaryocyte-potentiating factor
 Protein Family    Mesothelin
 UniProt Gene Name    MSLN [Similar Products]
 UniProt Synonym Gene Names    MPF; MPF [Similar Products]
 UniProt Entry Name    MSLN_HUMAN
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 NCBI Summary for MSLN    This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
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 UniProt Comments for MSLN    MSLN: Membrane-anchored forms may play a role in cellular adhesion. Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer. Belongs to the mesothelin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor; Cell adhesion

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: cell surface; extracellular space; Golgi apparatus; membrane; plasma membrane

Molecular Function: protein binding

Biological Process: cell adhesion; cell-matrix adhesion; pancreas development
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 Research Articles on MSLN    1. High mesothelin expression was strongly associated with mutant KRAS/wild-type EGFR and poor prognosis in advanced lung cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MSLN peptideDiseases associated with MSLN peptide
 Reference Product  PubMed Publications
 MUC16 peptide  >3 publications with MSLN and MUC16
 WFDC2 peptide  >2 publications with MSLN and WFDC2
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >23 publications with MSLN and Carcinoma
 Pancreatic Neoplasms Antibodies  >21 publications with MSLN and Pancreatic Neoplasms
 Mesothelioma Antibodies  >20 publications with MSLN and Mesothelioma
 Neoplasms, Mesothelial Antibodies  >18 publications with MSLN and Neoplasms, Mesothelial
 Ovarian Neoplasms Antibodies  >18 publications with MSLN and Ovarian Neoplasms
 Adenocarcinoma Antibodies  >18 publications with MSLN and Adenocarcinoma
 Lung Diseases Antibodies  >12 publications with MSLN and Lung Diseases
 Lung Neoplasms Antibodies  >10 publications with MSLN and Lung Neoplasms
 Carcinoma, Pancreatic Ductal Antibodies  >9 publications with MSLN and Carcinoma, Pancreatic Ductal
 Neoplasms, Experimental Antibodies  >8 publications with MSLN and Neoplasms, Experimental
Organs/Tissues associated with MSLN peptide
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >15 publications with MSLN and Lung
 Liver Antibodies  >6 publications with MSLN and Liver
 Pancreas Antibodies  >5 publications with MSLN and Pancreas
 Stomach Antibodies  >4 publications with MSLN and Stomach
 Ovary Antibodies  >3 publications with MSLN and Ovary
 Ascites Antibodies  >2 publications with MSLN and Ascites
 Intestine Antibodies  >2 publications with MSLN and Intestine
 Brain Antibodies  >1 publications with MSLN and Brain
 Prostate Antibodies  >1 publications with MSLN and Prostate
 Cervix Antibodies  >1 publications with MSLN and Cervix
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