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DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

NCDN peptide :: Neurochondrin Peptide

Scan QR to view Datasheet Catalog #    MBS426778 NCDN peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Neurochondrin (NCDN), Peptide

 Also Known As   

Neurochondrin Immunizing Peptide

 Product Synonym Names    NCDN; neurochondrin; KIAA0607; Neurochondrin; Neurochondrin
 Product Gene Name   

NCDN peptide

[Similar Products]
 Antibody/Peptide Pairs    Neurochondrin peptide (MBS426778) is used for blocking the activity of Neurochondrin antibody (MBS421400)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-HYLLQVGS EKQKEP
 OMIM    608458
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 Species Reactivity    Human, Mouse, Rat, Dog, Cow
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of NCDN peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for NCDN. It may not necessarily be applicable to this product.
 NCBI GI #    24307949
 NCBI GeneID    23154
 NCBI Accession #    NP_055099.1 [Other Products]
 NCBI Related Accession #    NP_001014841.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_014284.2 [Other Products]
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 UniProt Secondary Accession #    Q9UBY2; Q9Y4A6; Q9Y4D9; D3DPR9 [Other Products]
 UniProt Related Accession #    Q9UBB6 [Other Products]
 Molecular Weight    79,158 Da
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 NCBI Official Full Name    neurochondrin isoform 1
 NCBI Official Synonym Full Names    neurochondrin
 NCBI Official Symbol    NCDN [Similar Products]
 NCBI Protein Information    neurochondrin
 UniProt Protein Name    Neurochondrin
 Protein Family    Neurochondrin
 UniProt Gene Name    NCDN [Similar Products]
 UniProt Synonym Gene Names    KIAA0607 [Similar Products]
 UniProt Entry Name    NCDN_HUMAN
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 NCBI Summary for NCDN    This gene encodes a leucine-rich cytoplasmic protein, which is highly similar to a mouse protein that negatively regulates Ca/calmodulin-dependent protein kinase II phosphorylation and may be essential for spatial learning processes. Several alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NCDN    NCDN: Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin- concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth. Belongs to the neurochondrin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Inhibitor

Chromosomal Location of Human Ortholog: 1p34.3

Cellular Component: axon; cell soma; cytosol; dendrite; membrane; nucleus

Molecular Function: protein binding

Biological Process: bone resorption; neurite development; regulation of neuronal synaptic plasticity
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 Research Articles on NCDN    1. Schizophrenia subjects compared to controls showed a marked increase in CA1 hippocampal Norbin, and Tamalin proteins (47% and 34% respectively), which are endogenous regulators of mGluR5 signalling and trafficking
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NCDN peptideDiseases associated with NCDN peptide
 Reference Product  PubMed Publications
 NXPH3 peptide  >1 publications with NCDN and NXPH3
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >1 publications with NCDN and Cardiovascular Diseases
 Inflammation Antibodies  >1 publications with NCDN and Inflammation
 Necrosis Antibodies  >1 publications with NCDN and Necrosis
Organs/Tissues associated with NCDN peptide
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with NCDN and Brain
 Nerve Antibodies  >4 publications with NCDN and Nerve
 Blood Antibodies  >2 publications with NCDN and Blood
 Bone Antibodies  >2 publications with NCDN and Bone
 Uterus Antibodies  >1 publications with NCDN and Uterus
 Embryonic Tissue Antibodies  >1 publications with NCDN and Embryonic Tissue
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