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notch1a peptide

Scan QR to view Datasheet Catalog #    MBS425339 notch1a peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Notch1a, Peptide

 Also Known As   

Notch1a Immunizing Peptide

 Product Synonym Names    notch1a; notch homolog 1a; n1a; deadly seven; des; neurogenic locus notch homolog protein; Notch1a (zebrafish)
 Product Gene Name   

notch1a peptide

[Similar Products]
 Antibody/Peptide Pairs    Notch1a peptide (MBS425339) is used for blocking the activity of Notch1a antibody (MBS422065)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Species Reactivity    Zebrafish
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of notch1a peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for notch1a. It may not necessarily be applicable to this product.
 NCBI GI #    18859115
 NCBI GeneID    30718
 NCBI Accession #    NP_571516.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_131441.1 [Other Products]
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 UniProt Related Accession #    P46530 [Other Products]
 Molecular Weight    262,308 Da
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 NCBI Official Full Name    neurogenic locus notch homolog protein 1
 NCBI Official Synonym Full Names    notch 1a
 NCBI Official Symbol    notch1a [Similar Products]
 NCBI Official Synonym Symbols   
des; n1a; wu:fc01e02; wu:fc37a05
[Similar Products]
 NCBI Protein Information    neurogenic locus notch homolog protein 1
 UniProt Protein Name    Neurogenic locus notch homolog protein 1
 UniProt Gene Name    notch1a [Similar Products]
 UniProt Synonym Gene Names    notch; Notch 1; NEXT; NICD [Similar Products]
 UniProt Entry Name    NOTC1_DANRE
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 UniProt Comments for notch1a    Functions as a receptor for membrane-bound ligands jagged1, jagged2 and delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4+ and CD8+ cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia. Represses neuronal and myogenic differentiation. May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation. May be involved in mesoderm development, somite formation and neurogenesis (). Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO) ().
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 Research Articles on notch1a    1. Data show that angiopoietin-like proteins zangptl1 and 2 are required for definitive HSPCs formation, and genetically interact with notch receptor.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with notch1a peptideDiseases associated with notch1a peptide
 Products by Pathway  Pathway Diagram
 Activated NOTCH1 Transmits Signal To The Nucleus Pathway antibodies  Activated NOTCH1 Transmits Signal To The Nucleus Pathway Diagram
 Dorso-ventral Axis Formation Pathway antibodies  Dorso-ventral Axis Formation Pathway Diagram
 Dorso-ventral Axis Formation Pathway antibodies  Dorso-ventral Axis Formation Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Notch Signaling Pathway antibodies  Notch Signaling Pathway Diagram
 Notch Signaling Pathway antibodies  Notch Signaling Pathway Diagram
 Notch Signaling Pathway antibodies  Notch Signaling Pathway Diagram
 Notch Signaling Pathway antibodies  Notch Signaling Pathway Diagram
 Notch-HLH Transcription Pathway antibodies  Notch-HLH Transcription Pathway Diagram
 Disease Name  Pubmed Publications
 Hyperplasia Antibodies  >2 publications with notch1a and Hyperplasia
 Heart Failure Antibodies  >1 publications with notch1a and Heart Failure
 Heart Diseases Antibodies  >1 publications with notch1a and Heart Diseases
 Cardiovascular Diseases Antibodies  >1 publications with notch1a and Cardiovascular Diseases
 Heart Defects, Congenital Antibodies  >1 publications with notch1a and Heart Defects, Congenital
Organs/Tissues associated with notch1a peptide
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >4 publications with notch1a and Muscle
 Reproductive System Antibodies  >3 publications with notch1a and Reproductive System
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