Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Peptide rightarrow POU5F1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Potassium channel subfamily K member 3 (KCNK3) Recombinant Protein
 • MB21D1 Antibody
 • Pyruvate Carboxylase (PC) ELISA Kit
 • Thyroid Stimulating Hormone (TSHB) Recombinant Protein
 • Dihydrolipoyl Transacetylase (DLAT) ELISA Kit
 • ZADH2 Antibody
 • prolactin soluble receptor Recombinant Protein
 • GAPDH pAb Antibody
 • NR5A2 Antibody
 • Protein G Antibody
 • Haptoglobin (HPR) Protein
 • Aryl Hydrocarbon Receptor (AhR) Recombinant Protein
 • DNA, Salmon Sperm DNA
 • BCA Protein Assay Kit (Enhanced) Protein Assay Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

POU5F1 peptide :: OCT4 / POU5F1 Peptide

Scan QR to view Datasheet Catalog #    MBS425947 POU5F1 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

OCT4 / POU5F1, Peptide

 Also Known As   

OCT4 / POU5F1 Immunizing Peptide

 Product Synonym Names    POU5F1; OTF4; POU domain, class 5, transcription factor 1; HGNC: 9221; MGC22487; OCT3; OTF3; POU-type homeodomain-containing DNA-binding protein; octamer-binding transcription factor-3; POU class 5 homeobox 1; DADB-104B20.2; OCT4; POU domain, class 5, tran; OCT4 / POU5F1
 Product Gene Name   

POU5F1 peptide

[Similar Products]
 Product Synonym Gene Name    OCT4 [Similar Products]
 Antibody/Peptide Pairs    OCT4 / POU5F1 peptide (MBS425947) is used for blocking the activity of OCT4/POU5F1 antibody (MBS420786)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    C-VTTLGSPM HSN
 OMIM    164177
Section Bar
 Species Reactivity    Human, Mouse, Rat, Dog
Section Bar
 Form/Format    100ug of dried peptide
Section Bar
Section Bar
 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of POU5F1 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for POU5F1. It may not necessarily be applicable to this product.
 NCBI GI #    42560248
 NCBI GeneID    5460
 NCBI Accession #    NP_002692.2 [Other Products]
 NCBI Related Accession #    NP_976034.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_002701.5 [Other Products]
Section Bar
 UniProt Secondary Accession #    P31359; Q15167; Q15168; Q16422; Q5STF3; Q5STF4; A6NCS1; A6NLL8; D2IYK4 [Other Products]
 UniProt Related Accession #    Q01860 [Other Products]
 Molecular Weight    30,085 Da
Table BarTOPTable Bar
 NCBI Official Full Name    POU domain, class 5, transcription factor 1 isoform 1
 NCBI Official Synonym Full Names    POU class 5 homeobox 1
 NCBI Official Symbol    POU5F1 [Similar Products]
 NCBI Official Synonym Symbols   
OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4
[Similar Products]
 NCBI Protein Information    POU domain, class 5, transcription factor 1
 UniProt Protein Name    POU domain, class 5, transcription factor 1
 UniProt Synonym Protein Names   
Octamer-binding protein 3; Oct-3; Octamer-binding protein 4; Oct-4; Octamer-binding transcription factor 3; OTF-3
 Protein Family    POU domain, class 5, transcription factor
 UniProt Gene Name    POU5F1 [Similar Products]
 UniProt Synonym Gene Names    OCT3; OCT4; OTF3; Oct-3; Oct-4; OTF-3 [Similar Products]
 UniProt Entry Name    PO5F1_HUMAN
Section Bar
 NCBI Summary for POU5F1    This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]
Section Bar
 UniProt Comments for POU5F1    Oct4: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Interacts with UBE2I and ZSCAN10. Interacts with PKM2. Interacts with WWP2. Transcriptional activity is positively regulated by PKM2. Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues. Belongs to the POU transcription factor family. Class- 5 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 6p21.31

Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus; transcription factor complex

Molecular Function: DNA binding; miRNA binding; protein binding; sequence-specific DNA binding; transcription factor activity; transcription factor binding; ubiquitin protein ligase binding

Biological Process: anatomical structure morphogenesis; blastocyst development; endodermal cell fate specification; mRNA transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; regulation of asymmetric cell division; regulation of gene expression; regulation of transcription, DNA-dependent; response to wounding; somatic stem cell maintenance; transcription from RNA polymerase II promoter
Table BarTOPTable Bar
 Research Articles on POU5F1    1. patients with OCT4 high expression have significantly shorter overall survival (OS) than those without OCT4 high expression (P = 0.048). These findings suggest that OCT4 high expression is a common event and may have an adverse impact on prognosis in AML.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with POU5F1 peptidePathways associated with POU5F1 peptide
 Reference Product  PubMed Publications
 SOX2 peptide  >960 publications with POU5F1 and SOX2
 NANOG peptide  >905 publications with POU5F1 and NANOG
 KLF4 peptide  >318 publications with POU5F1 and KLF4
 CDX2 peptide  >90 publications with POU5F1 and CDX2
 SALL4 peptide  >37 publications with POU5F1 and SALL4
 LIN28A peptide  >4 publications with POU5F1 and LIN28A
 ETS2 peptide  >3 publications with POU5F1 and ETS2
 ZSCAN10 peptide  >2 publications with POU5F1 and ZSCAN10
 NR5A1 peptide  >2 publications with POU5F1 and NR5A1
 EPAS1 peptide  >1 publications with POU5F1 and EPAS1
 Products by Pathway  Pathway Diagram
 Cardiac Progenitor Differentiation Pathway antibodies  Cardiac Progenitor Differentiation Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 HIF-2-alpha Transcription Factor Network Pathway antibodies  HIF-2-alpha Transcription Factor Network Pathway Diagram
 POU5F1 (OCT4), SOX2, NANOG Activate Genes Related To Proliferation Pathway antibodies  POU5F1 (OCT4), SOX2, NANOG Activate Genes Related To Proliferation Pathway Diagram
 POU5F1 (OCT4), SOX2, NANOG Repress Genes Related To Differentiation Pathway antibodies  POU5F1 (OCT4), SOX2, NANOG Repress Genes Related To Differentiation Pathway Diagram
 SIDS Susceptibility Pathways antibodies  SIDS Susceptibility Pathways Diagram
 Signaling Pathways Regulating Pluripotency Of Stem Cells antibodies  Signaling Pathways Regulating Pluripotency Of Stem Cells Diagram
 Signaling Pathways Regulating Pluripotency Of Stem Cells antibodies  Signaling Pathways Regulating Pluripotency Of Stem Cells Diagram
 Transcriptional Regulation Of Pluripotent Stem Cells Pathway antibodies  Transcriptional Regulation Of Pluripotent Stem Cells Pathway Diagram
 Wnt Signaling Pathway And Pluripotency antibodies  Wnt Signaling Pathway And Pluripotency Diagram
Diseases associated with POU5F1 peptideOrgans/Tissues associated with POU5F1 peptide
 Disease Name  Pubmed Publications
 Neoplasms, Germ Cell and Embryonal Antibodies  >381 publications with POU5F1 and Neoplasms, Germ Cell and Embryonal
 Neoplasm Metastasis Antibodies  >84 publications with POU5F1 and Neoplasm Metastasis
 Lung Diseases Antibodies  >71 publications with POU5F1 and Lung Diseases
 Lung Neoplasms Antibodies  >70 publications with POU5F1 and Lung Neoplasms
 Brain Diseases Antibodies  >67 publications with POU5F1 and Brain Diseases
 Breast Neoplasms Antibodies  >62 publications with POU5F1 and Breast Neoplasms
 Ovarian Neoplasms Antibodies  >55 publications with POU5F1 and Ovarian Neoplasms
 Neoplasms, Experimental Antibodies  >50 publications with POU5F1 and Neoplasms, Experimental
 Liver Diseases Antibodies  >48 publications with POU5F1 and Liver Diseases
 Chromosome Aberrations Antibodies  >42 publications with POU5F1 and Chromosome Aberrations
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >604 publications with POU5F1 and Embryonic Tissue
 Testis Antibodies  >180 publications with POU5F1 and Testis
 Brain Antibodies  >153 publications with POU5F1 and Brain
 Lung Antibodies  >108 publications with POU5F1 and Lung
 Liver Antibodies  >106 publications with POU5F1 and Liver
 Ovary Antibodies  >95 publications with POU5F1 and Ovary
 Uterus Antibodies  >27 publications with POU5F1 and Uterus
 Stomach Antibodies  >27 publications with POU5F1 and Stomach
 Mammary Gland Antibodies  >13 publications with POU5F1 and Mammary Gland
 Uncharacterized Tissue Antibodies  >1 publications with POU5F1 and Uncharacterized Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions