NP_031372.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
71,424 Da
NCBI Official Full Name
opioid growth factor receptor
NCBI Official Synonym Full Names
opioid growth factor receptor
NCBI Protein Information
opioid growth factor receptor
UniProt Protein Name
Opioid growth factor receptor
UniProt Synonym Protein Names
Protein 7-60; Zeta-type opioid receptor
UniProt Synonym Gene Names
UniProt Entry Name
OGFR_HUMAN
NCBI Summary for OGFR
The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008]
UniProt Comments for OGFR
OGFR: Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation. Belongs to the opioid growth factor receptor family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, misc.
Chromosomal Location of Human Ortholog: 20q13.3
Cellular Component: cytoplasm; membrane; nucleus
Molecular Function: opioid receptor activity; protein binding
Biological Process: regulation of cell growth
Research Articles on OGFR
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Diseases associated with OGFR blocking peptide
Organs/Tissues associated with OGFR blocking peptide
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