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OSBPL2 peptide :: ORP2 Peptide

Scan QR to view Datasheet Catalog #    MBS425565 OSBPL2 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ORP2 (OSBPL2), Peptide

 Also Known As   

ORP2 Immunizing Peptide

 Product Synonym Names    OSBPL2; ORP2; ORP-2; MGC4307; MGC8342; FLJ20223; KIAA0772; oxysterol binding protein-like 2; OSBP-related protein 2; oxysterol-binding protein-related protein 2; oxysterol-binding protein-like protein 2
 Product Gene Name   

OSBPL2 peptide

[Similar Products]
 Product Synonym Gene Name    ORP2 [Similar Products]
 Antibody/Peptide Pairs    ORP2 peptide (MBS425565) is used for blocking the activity of ORP2 antibody (MBS420292)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    YFERNFSDCP DIY
 OMIM    606731
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 Species Reactivity    Human, Mouse, Rat
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of OSBPL2 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for OSBPL2. It may not necessarily be applicable to this product.
 NCBI GI #    7662298
 NCBI GeneID    9885
 NCBI Accession #    NP_055650.1 [Other Products]
 NCBI Related Accession #    NP_653081.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_014835.3 [Other Products]
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 UniProt Secondary Accession #    Q6IBT0; Q9BZB1; Q9Y4B8; A8K736 [Other Products]
 UniProt Related Accession #    Q9H1P3 [Other Products]
 Molecular Weight    53,971 Da
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 NCBI Official Full Name    oxysterol-binding protein-related protein 2 isoform 1
 NCBI Official Synonym Full Names    oxysterol binding protein like 2
 NCBI Official Symbol    OSBPL2 [Similar Products]
 NCBI Official Synonym Symbols   
ORP2; ORP-2; DFNA67; DNFA67
[Similar Products]
 NCBI Protein Information    oxysterol-binding protein-related protein 2
 UniProt Protein Name    Oxysterol-binding protein-related protein 2
 Protein Family    Oxysterol-binding protein-related protein
 UniProt Gene Name    OSBPL2 [Similar Products]
 UniProt Synonym Gene Names    KIAA0772; ORP2; ORP-2; OSBP-related protein 2 [Similar Products]
 UniProt Entry Name    OSBL2_HUMAN
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 NCBI Summary for OSBPL2    This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]
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 UniProt Comments for OSBPL2    OSBPL2: Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate. Belongs to the OSBP family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 20q13.33

Molecular Function: cholesterol binding; protein binding

Biological Process: lipid transport

Disease: Deafness, Autosomal Dominant 67
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 Research Articles on OSBPL2    1. This study and the recent description of another frameshift mutation in a Chinese ADNSHL family identify OSBPL2 as a novel gene for progressive deafness.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with OSBPL2 peptideDiseases associated with OSBPL2 peptide
 Reference Product  PubMed Publications
 VAPA peptide  >1 publications with OSBPL2 and VAPA
 VAPB peptide  >1 publications with OSBPL2 and VAPB
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with OSBPL2 and Nervous System Diseases
Organs/Tissues associated with OSBPL2 peptide
 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >3 publications with OSBPL2 and Ovary
 Adrenal Gland Antibodies  >1 publications with OSBPL2 and Adrenal Gland
 Adipose Tissue Antibodies  >1 publications with OSBPL2 and Adipose Tissue
 Liver Antibodies  >1 publications with OSBPL2 and Liver
 Blood Antibodies  >1 publications with OSBPL2 and Blood
 Eye Antibodies  >1 publications with OSBPL2 and Eye
 Brain Antibodies  >1 publications with OSBPL2 and Brain
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