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OSCAR peptide

Scan QR to view Datasheet Catalog #    MBS425861 OSCAR peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

OSCAR, Peptide

 Also Known As   

OSCAR Immunizing Peptide

 Product Synonym Names    OSCAR; osteoclast-associated receptor; MGC33613; PIGR3; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; polymeric immunoglobulin receptor 3 precursor; OSCAR (Isoform 1)
 Product Gene Name   

OSCAR peptide

[Similar Products]
 Antibody/Peptide Pairs    OSCAR peptide (MBS425861) is used for blocking the activity of OSCAR antibody (MBS421501)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-EGPEARPA SSAP
 OMIM    606862
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of OSCAR peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for OSCAR. It may not necessarily be applicable to this product.
 NCBI GI #    45580719
 NCBI GeneID    126014
 NCBI Accession #    NP_996554.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_206818.1 [Other Products]
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 UniProt Secondary Accession #    Q5GRG5; Q8N763; Q8NHL4; Q8WXQ0; Q8WXQ1; Q8WXQ2; B7WNS2 [Other Products]
 UniProt Related Accession #    Q8IYS5 [Other Products]
 Molecular Weight    27,629 Da
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 NCBI Official Full Name    osteoclast-associated immunoglobulin-like receptor isoform 1
 NCBI Official Synonym Full Names    osteoclast associated, immunoglobulin-like receptor
 NCBI Official Symbol    OSCAR [Similar Products]
 NCBI Official Synonym Symbols   
PIGR3; PIgR-3
[Similar Products]
 NCBI Protein Information    osteoclast-associated immunoglobulin-like receptor
 UniProt Protein Name    Osteoclast-associated immunoglobulin-like receptor
 UniProt Synonym Protein Names   
Polymeric immunoglobulin receptor 3; PIgR-3; PIgR3; Poly-Ig receptor 3
 Protein Family    Osteoclast-associated immunoglobulin-like receptor
 UniProt Gene Name    OSCAR [Similar Products]
 UniProt Synonym Gene Names    Osteoclast-associated receptor; hOSCAR; PIgR-3; PIgR3; Poly-Ig receptor 3 [Similar Products]
 UniProt Entry Name    OSCAR_HUMAN
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 NCBI Summary for OSCAR    Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
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 UniProt Comments for OSCAR    OSCAR: Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation. Belongs to the leukocyte receptor complex/polymeric immunogobulin receptor (PIR/LRC) family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: extracellular region; integral to membrane; plasma membrane

Biological Process: regulation of immune response
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 Research Articles on OSCAR    1. OSCAR is a receptor for surfactant protein D that activates TNF-alpha release from human CCR2+ inflammatory monocytes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with OSCAR peptideDiseases associated with OSCAR peptide
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >132 publications with OSCAR and Cardiovascular Diseases
 Lung Diseases Antibodies  >121 publications with OSCAR and Lung Diseases
 Pain Antibodies  >105 publications with OSCAR and Pain
 Vascular Diseases Antibodies  >102 publications with OSCAR and Vascular Diseases
 Lung Neoplasms Antibodies  >81 publications with OSCAR and Lung Neoplasms
 Bone Resorption Antibodies  >58 publications with OSCAR and Bone Resorption
 Inflammation Antibodies  >51 publications with OSCAR and Inflammation
 Necrosis Antibodies  >49 publications with OSCAR and Necrosis
 Hypertension Antibodies  >45 publications with OSCAR and Hypertension
 Kidney Diseases Antibodies  >40 publications with OSCAR and Kidney Diseases
Organs/Tissues associated with OSCAR peptide
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >314 publications with OSCAR and Blood
 Brain Antibodies  >176 publications with OSCAR and Brain
 Lung Antibodies  >136 publications with OSCAR and Lung
 Heart Antibodies  >102 publications with OSCAR and Heart
 Liver Antibodies  >85 publications with OSCAR and Liver
 Skin Antibodies  >80 publications with OSCAR and Skin
 Bone Marrow Antibodies  >59 publications with OSCAR and Bone Marrow
 Eye Antibodies  >47 publications with OSCAR and Eye
 Connective Tissue Antibodies  >33 publications with OSCAR and Connective Tissue
 Uterus Antibodies  >20 publications with OSCAR and Uterus
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