View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List Obestatin, aa1-23 Peptide Catalog # MBS659976 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Obestatin, aa1-23, Peptide Full Product Name Obestatin, Human, aa1-23 (Appetite-regulating Hormone, Growth Hormone Secretagogue, Growth Hormone-releasing Peptide, Motilin-related Peptide, Protein M46, Ghrelin, GHRL, MTLRP, UNQ524/PRO1066) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence F-N-A-P-F- D-V-G-I-K- L-S-G-V-Q- Y-Q-Q- H-S-Q-A-L- NH2 Purity/Purification Purified~95% (HPLC) Form/Format Supplied as a lyophilized powder. Reconstitute with ddH2O. Molecular Formula C114H174N34O31 Solubility Soluble in dH2O Preparation and Storage Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Other Notes Small volumes of Obestatin, aa1-23 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for Obestatin, aa1-23 peptide Control of appetite involves a number of gastrointestinal hormones that belong to the Ghrelin-motilin ligand family that either stimulate food intake and gastric emptying or inhibit these responses.Obestatin, a ghrelin-associated peptide, has recently been discovered by searching for orthologs of the human ghrelin gene and after comparison of preproghrelin sequences from 11 mammalian species. In addition to the known ghrelin peptide, which immediately follows the signal peptide, the researchers identified another conserved region. This region was flanked by a potential convertase cleavage site, which originated a putative 23aa peptide, with a flanking conserved glycine residue at the C- terminal, suggesting that it might be amidated.Interestingly, Des 1-10 Obestatin (C-terminal 11-23aa) - a truncated peptide of obestatin was shown to have a lower binding affinity to its receptor GPR39 as compared to the full length obestatin. GPR39 mRNA is prominently expressed in the ventral hippocampus, specifically the CA1, which is known to project to the basolateral and basomedial amygdaloid nuclei, which also express GPR39 mRNA. Contextual conditioning is disrupted when any of these nuclei are damaged, indicating that activation of the GPR39 system may modulate this response.Reports that GPR39 is a cognate receptor for Obestatin were recently contradicted warning for more prudent approach to investigation. Product Categories/Family for Obestatin, aa1-23 peptide Molecular Biology; MB-Obesity Molecular Weight 2620.76[Similar Products] TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP