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P2RY1 peptide

Scan QR to view Datasheet Catalog #    MBS426985 P2RY1 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

P2RY1, Peptide

 Also Known As   

P2RY1 Immunizing Peptide

 Product Synonym Names    P2RY1; purinergic receptor P2Y, G-protein coupled, 1; P2Y1; ATP receptor; P2 purinoceptor subtype Y1; P2Y purinoceptor 1; platelet ADP receptor; purinergic receptor P2Y1; P2RY1 (aa345-356)
 Product Gene Name   

P2RY1 peptide

[Similar Products]
 Antibody/Peptide Pairs    P2RY1 peptide (MBS426985) is used for blocking the activity of P2RY1 antibody (MBS421632)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-RSEANLQS KSED
 OMIM    601167
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 Species Reactivity    Human, Mouse, Rat, Dog
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of P2RY1 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for P2RY1. It may not necessarily be applicable to this product.
 NCBI GI #    4505557
 NCBI GeneID    5028
 NCBI Accession #    NP_002554.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002563.4 [Other Products]
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 UniProt Related Accession #    P47900 [Other Products]
 Molecular Weight    42,072 Da
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 NCBI Official Full Name    P2Y purinoceptor 1
 NCBI Official Synonym Full Names    purinergic receptor P2Y1
 NCBI Official Symbol    P2RY1 [Similar Products]
 NCBI Official Synonym Symbols   
P2Y1
[Similar Products]
 NCBI Protein Information    P2Y purinoceptor 1
 UniProt Protein Name    P2Y purinoceptor 1
 UniProt Synonym Protein Names   
ATP receptor; Purinergic receptor
 Protein Family    P2Y purinoceptor
 UniProt Gene Name    P2RY1 [Similar Products]
 UniProt Synonym Gene Names    P2Y1 [Similar Products]
 UniProt Entry Name    P2RY1_HUMAN
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 NCBI Summary for P2RY1    The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for P2RY1    P2RY1: Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 3q25.2

Cellular Component: apical plasma membrane; basolateral plasma membrane; cell surface; cytosol; dendrite; integral to plasma membrane; mitochondrion; plasma membrane; postsynaptic membrane

Molecular Function: A1 adenosine receptor binding; ADP binding; ADP-activated nucleotide receptor activity; ATP binding; ATP-activated nucleotide receptor activity; protein binding; protein heterodimerization activity; purinergic nucleotide receptor activity, G-protein coupled; receptor activity

Biological Process: adenosine receptor signaling pathway; aging; cell surface receptor linked signal transduction; eating behavior; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); glial cell migration; negative regulation of binding; platelet activation; positive regulation of hormone secretion; positive regulation of inositol trisphosphate biosynthetic process; positive regulation of ion transport; positive regulation of protein amino acid phosphorylation; positive regulation of transcription from RNA polymerase II promoter; regulation of receptor activity; regulation of vasodilation; response to mechanical stimulus; sensory perception of pain
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 Research Articles on P2RY1    1. Antibody EL2Ab binds to and exhibits P2Y1R-dependent function-blocking activity in the context of platelets.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with P2RY1 peptidePathways associated with P2RY1 peptide
 Reference Product  PubMed Publications
 ADORA1 peptide  >11 publications with P2RY1 and ADORA1
 TBXA2R peptide  >3 publications with P2RY1 and TBXA2R
 P2RX1 peptide  >1 publications with P2RY1 and P2RX1
 GRM5 peptide  >1 publications with P2RY1 and GRM5
 Products by Pathway  Pathway Diagram
 ADP Signalling Through P2Y Purinoceptor 1 Pathway antibodies  ADP Signalling Through P2Y Purinoceptor 1 Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with P2RY1 peptideOrgans/Tissues associated with P2RY1 peptide
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >38 publications with P2RY1 and Cardiovascular Diseases
 Thrombosis Antibodies  >35 publications with P2RY1 and Thrombosis
 Kidney Diseases Antibodies  >17 publications with P2RY1 and Kidney Diseases
 Disease Models, Animal Antibodies  >15 publications with P2RY1 and Disease Models, Animal
 Inflammation Antibodies  >15 publications with P2RY1 and Inflammation
 Atherosclerosis Antibodies  >8 publications with P2RY1 and Atherosclerosis
 Fibrosis Antibodies  >7 publications with P2RY1 and Fibrosis
 Lung Diseases Antibodies  >4 publications with P2RY1 and Lung Diseases
 Necrosis Antibodies  >4 publications with P2RY1 and Necrosis
 Carcinoma Antibodies  >2 publications with P2RY1 and Carcinoma
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >87 publications with P2RY1 and Brain
 Vascular Antibodies  >63 publications with P2RY1 and Vascular
 Intestine Antibodies  >22 publications with P2RY1 and Intestine
 Embryonic Tissue Antibodies  >14 publications with P2RY1 and Embryonic Tissue
 Liver Antibodies  >13 publications with P2RY1 and Liver
 Mouth Antibodies  >9 publications with P2RY1 and Mouth
 Lung Antibodies  >7 publications with P2RY1 and Lung
 Placenta Antibodies  >6 publications with P2RY1 and Placenta
 Prostate Antibodies  >3 publications with P2RY1 and Prostate
 Uncharacterized Tissue Antibodies  >1 publications with P2RY1 and Uncharacterized Tissue
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