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PAX5 peptide :: PAX5 / BSAP Peptide

Scan QR to view Datasheet Catalog #    MBS425077 PAX5 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PAX5 / BSAP, Peptide

 Also Known As   

PAX5 / BSAP Immunizing Peptide

 Product Synonym Names    PAX5; BSAP; paired box gene 5 (B-cell lineage specific activator protein); B-cell lineage specific activator protein; paired box homeotic gene 5 (B-cell lineage specific activator protein); paired box 5; B cell specific activator protein; B-cell lineage s; PAX5 / BSAP
 Product Gene Name   

PAX5 peptide

[Similar Products]
 Product Synonym Gene Name    BSAP [Similar Products]
 Antibody/Peptide Pairs    PAX5 / BSAP peptide (MBS425077) is used for blocking the activity of PAX5/BSAP antibody (MBS421040)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    DLEKNYPTPR TSR-C
 OMIM    167414
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 Species Reactivity    Human, Mouse
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of PAX5 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for PAX5. It may not necessarily be applicable to this product.
 NCBI GI #    9951920
 NCBI GeneID    5079
 NCBI Accession #    NP_057953.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_016734.2 [Other Products]
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 UniProt Secondary Accession #    O75933; Q5SFM2; Q6S728; A3QVP6; A3QVP7; A3QVP8; C0KTF6; C0KTF7; C0KTF8; C0KTF9; C0KTG0 [Other Products]
 UniProt Related Accession #    Q02548 [Other Products]
 Molecular Weight    34,132 Da
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 NCBI Official Full Name    paired box protein Pax-5 isoform 1
 NCBI Official Synonym Full Names    paired box 5
 NCBI Official Symbol    PAX5 [Similar Products]
 NCBI Official Synonym Symbols   
ALL3; BSAP
[Similar Products]
 NCBI Protein Information    paired box protein Pax-5
 UniProt Protein Name    Paired box protein Pax-5
 UniProt Synonym Protein Names   
B-cell-specific transcription factor; BSAP
 Protein Family    Paired box protein
 UniProt Gene Name    PAX5 [Similar Products]
 UniProt Synonym Gene Names    BSAP [Similar Products]
 UniProt Entry Name    PAX5_HUMAN
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 NCBI Summary for PAX5    This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
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 UniProt Comments for PAX5    PAX5: May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene. Interacts with DAXX. Binds DNA as a monomer. Binds TLE4.

Protein type: Oncoprotein

Chromosomal Location of Human Ortholog: 9p13

Molecular Function: protein binding

Biological Process: humoral immune response; multicellular organismal development; organ morphogenesis; transcription from RNA polymerase II promoter

Disease: Leukemia, Acute Lymphoblastic, Susceptibility To, 3
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 Research Articles on PAX5    1. This is the first reported case of a novel complex variant translocation of t(11;14)(q13;q32) and t(9;14)(p13;q32)in PAX5-positive plasma cell myeloma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PAX5 peptidePathways associated with PAX5 peptide
 Reference Product  PubMed Publications
 EBF1 peptide  >112 publications with PAX5 and EBF1
 PRDM1 peptide  >58 publications with PAX5 and PRDM1
 RUNX1 peptide  >31 publications with PAX5 and RUNX1
 RAG2 peptide  >27 publications with PAX5 and RAG2
 ETS1 peptide  >11 publications with PAX5 and ETS1
 LEF1 peptide  >10 publications with PAX5 and LEF1
 MYB peptide  >7 publications with PAX5 and MYB
 DAXX peptide  >5 publications with PAX5 and DAXX
 STAT5A peptide  >3 publications with PAX5 and STAT5A
 TLE4 peptide  >1 publications with PAX5 and TLE4
 Products by Pathway  Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Id Signaling Pathway antibodies  Id Signaling Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
Diseases associated with PAX5 peptideOrgans/Tissues associated with PAX5 peptide
 Disease Name  Pubmed Publications
 Precursor Cell Lymphoblastic Leukemia-Lymphoma Antibodies  >118 publications with PAX5 and Precursor Cell Lymphoblastic Leukemia-Lymphoma
 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma Antibodies  >97 publications with PAX5 and Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
 Cell Transformation, Neoplastic Antibodies  >43 publications with PAX5 and Cell Transformation, Neoplastic
 Nervous System Diseases Antibodies  >28 publications with PAX5 and Nervous System Diseases
 Skin Neoplasms Antibodies  >23 publications with PAX5 and Skin Neoplasms
 Death Antibodies  >23 publications with PAX5 and Death
 Lung Neoplasms Antibodies  >21 publications with PAX5 and Lung Neoplasms
 Disease Models, Animal Antibodies  >17 publications with PAX5 and Disease Models, Animal
 Hyperplasia Antibodies  >16 publications with PAX5 and Hyperplasia
 Breast Neoplasms Antibodies  >15 publications with PAX5 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >91 publications with PAX5 and Lymph Node
 Lymph Antibodies  >69 publications with PAX5 and Lymph
 Spleen Antibodies  >49 publications with PAX5 and Spleen
 Eye Antibodies  >26 publications with PAX5 and Eye
 Tonsil Antibodies  >12 publications with PAX5 and Tonsil
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