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PLA2G1B peptide

Scan QR to view Datasheet Catalog #    MBS425980 PLA2G1B peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PLA2G1B, Peptide

★Popular Item★
 Also Known As   

PLA2G1B Immunizing Peptide

 Product Synonym Names    PLA2G1B; phospholipase A2, group IB (pancreas); MGC119834; MGC119835; PLA2; PLA2A; PPLA2; phospholipase A2, group IB;
 Product Gene Name   

PLA2G1B peptide

[Similar Products]
 Antibody/Peptide Pairs    PLA2G1B peptide (MBS425980) is used for blocking the activity of PLA2G1B antibody (MBS420861)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    NKAHKNLDTK KYCQS
 OMIM    172410
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 Species Reactivity    Human, Dog
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of PLA2G1B peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for PLA2G1B. It may not necessarily be applicable to this product.
 NCBI GI #    4505847
 NCBI GeneID    5319
 NCBI Accession #    NP_000919.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000928.2 [Other Products]
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 UniProt Secondary Accession #    Q3KPI1; B2R4H5 [Other Products]
 UniProt Related Accession #    P04054 [Other Products]
 Molecular Weight    16,360 Da
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 NCBI Official Full Name    phospholipase A2
 NCBI Official Synonym Full Names    phospholipase A2 group IB
 NCBI Official Symbol    PLA2G1B [Similar Products]
 NCBI Official Synonym Symbols   
PLA2; PLA2A; PPLA2
[Similar Products]
 NCBI Protein Information    phospholipase A2
 UniProt Protein Name    Phospholipase A2
 UniProt Synonym Protein Names   
Group IB phospholipase A2; Phosphatidylcholine 2-acylhydrolase 1B
 Protein Family    Phospholipase
 UniProt Gene Name    PLA2G1B [Similar Products]
 UniProt Synonym Gene Names    PLA2; PLA2A; PPLA2 [Similar Products]
 UniProt Entry Name    PA21B_HUMAN
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 NCBI Summary for PLA2G1B    This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. [provided by RefSeq, Aug 2013]
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 UniProt Comments for PLA2G1B    PLA2G1B: PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Belongs to the phospholipase A2 family.

Protein type: Lipid Metabolism - alpha-linolenic acid; Phospholipase; Lipid Metabolism - arachidonic acid; DNA replication; Secreted, signal peptide; EC 3.1.1.4; Lipid Metabolism - linoleic acid; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Secreted

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: cell surface; extracellular region; extracellular space; secretory granule

Molecular Function: bile acid binding; calcium ion binding; calcium-dependent phospholipase A2 activity; phospholipase A2 activity; receptor binding

Biological Process: actin filament organization; activation of MAPK activity; activation of NF-kappaB transcription factor; activation of phospholipase A2; antibacterial humoral response; arachidonic acid secretion; cellular response to insulin stimulus; defense response to Gram-positive bacterium; fatty acid biosynthetic process; glucose transport; innate immune response in mucosa; interleukin-8 production; leukotriene biosynthetic process; multicellular organismal lipid catabolic process; neutrophil chemotaxis; neutrophil mediated immunity; phosphatidic acid biosynthetic process; phosphatidylcholine metabolic process; positive regulation of DNA replication; positive regulation of fibroblast proliferation; positive regulation of immune response; positive regulation of protein secretion; positive regulation of transcription from RNA polymerase II promoter; signal transduction
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 Research Articles on PLA2G1B    1. The sPLA2 IB-PLA2R interaction stimulated podocyte apoptosis through activating ERK1/2 and cPLA2alpha and through increasing the podocyte AA content
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PLA2G1B peptideDiseases associated with PLA2G1B peptide
 Products by Pathway  Pathway Diagram
 Acyl Chain Remodelling Of PC Pathway antibodies  Acyl Chain Remodelling Of PC Pathway Diagram
 Acyl Chain Remodelling Of PE Pathway antibodies  Acyl Chain Remodelling Of PE Pathway Diagram
 Acyl Chain Remodelling Of PG Pathway antibodies  Acyl Chain Remodelling Of PG Pathway Diagram
 Acyl Chain Remodelling Of PI Pathway antibodies  Acyl Chain Remodelling Of PI Pathway Diagram
 Acyl Chain Remodelling Of PS Pathway antibodies  Acyl Chain Remodelling Of PS Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >8 publications with PLA2G1B and Inflammation
 Weight Gain Antibodies  >3 publications with PLA2G1B and Weight Gain
 Lung Diseases Antibodies  >3 publications with PLA2G1B and Lung Diseases
 Hypertension Antibodies  >2 publications with PLA2G1B and Hypertension
 Atherosclerosis Antibodies  >2 publications with PLA2G1B and Atherosclerosis
 Fatty Liver Antibodies  >2 publications with PLA2G1B and Fatty Liver
 Cardiovascular Diseases Antibodies  >2 publications with PLA2G1B and Cardiovascular Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with PLA2G1B and Carcinoma, Hepatocellular
 Adenocarcinoma Antibodies  >1 publications with PLA2G1B and Adenocarcinoma
 Hemorrhage Antibodies  >1 publications with PLA2G1B and Hemorrhage
Organs/Tissues associated with PLA2G1B peptide
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >5 publications with PLA2G1B and Pancreas
 Testis Antibodies  >2 publications with PLA2G1B and Testis
 Kidney Antibodies  >1 publications with PLA2G1B and Kidney
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