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PSMB9 peptide

Scan QR to view Datasheet Catalog #    MBS427637 PSMB9 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PSMB9, Peptide

 Also Known As   

PSMB9 Immunizing Peptide

 Product Synonym Names    PSMB9; proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2); LMP2; MGC70470; PSMB6i; RING12; beta1i; low molecular mass protein 2; macropain chain 7; multicatalytic endopeptidase complex chain 7; proteasome beta 9 subu
 Product Gene Name   

PSMB9 peptide

[Similar Products]
 Antibody/Peptide Pairs    PSMB9 peptide (MBS427637) is used for blocking the activity of PSMB9 antibody (MBS422475)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-RNISYKYR ED
 OMIM    177045
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 Species Reactivity    Human, Mouse, Rat, Dog, Cow, Pig, Rabbit
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of PSMB9 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for PSMB9. It may not necessarily be applicable to this product.
 NCBI GI #    4506205
 NCBI GeneID    5698
 NCBI Accession #    NP_002791.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002800.4 [Other Products]
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 UniProt Secondary Accession #    Q16523; Q5JNW4; B0V0T1 [Other Products]
 UniProt Related Accession #    P28065 [Other Products]
 Molecular Weight    22,328 Da
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 NCBI Official Full Name    proteasome subunit beta type-9
 NCBI Official Synonym Full Names    proteasome subunit beta 9
 NCBI Official Symbol    PSMB9 [Similar Products]
 NCBI Official Synonym Symbols   
LMP2; PSMB6i; RING12; beta1i
[Similar Products]
 NCBI Protein Information    proteasome subunit beta type-9
 UniProt Protein Name    Proteasome subunit beta type-9
 UniProt Synonym Protein Names   
Low molecular mass protein 2; Macropain chain 7; Multicatalytic endopeptidase complex chain 7; Proteasome chain 7; Proteasome subunit beta-1i; Really interesting new gene 12 protein
 Protein Family    Proteasome
 UniProt Gene Name    PSMB9 [Similar Products]
 UniProt Synonym Gene Names    LMP2; PSMB6i; RING12 [Similar Products]
 UniProt Entry Name    PSB9_HUMAN
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 NCBI Summary for PSMB9    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. [provided by RefSeq, Mar 2010]
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 UniProt Comments for PSMB9    PSMB9: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. Belongs to the peptidase T1B family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.25.1; Nuclear receptor co-regulator; Protease; Proteasome complex

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: cytoplasm; cytosol; nucleoplasm; proteasome complex; proteasome core complex

Molecular Function: protein binding; threonine endopeptidase activity

Biological Process: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; liver development; MAPKKK cascade; muscle atrophy; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; regulation of amino acid metabolic process; regulation of mRNA stability; response to alkaloid; response to drug; spleen development; stimulatory C-type lectin receptor signaling pathway; T cell receptor signaling pathway; thymus development; tumor necrosis factor-mediated signaling pathway; viral reproduction; Wnt receptor signaling pathway, planar cell polarity pathway
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 Research Articles on PSMB9    1. The TAP1-rs1135216 and PSMB9-rs17587 variants are significantly associated with vitiligo, and even one copy of these mutant alleles can influence the risk among Saudis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PSMB9 peptideDiseases associated with PSMB9 peptide
 Products by Pathway  Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Securin Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Securin Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies  APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
 APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway antibodies  APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 AUF1 (hnRNP D0) Binds And Destabilizes MRNA Pathway antibodies  AUF1 (hnRNP D0) Binds And Destabilizes MRNA Pathway Diagram
 Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 Activation Of NF-kappaB In B Cells Pathway antibodies  Activation Of NF-kappaB In B Cells Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >4 publications with PSMB9 and Kidney Diseases
 Inflammation Antibodies  >4 publications with PSMB9 and Inflammation
 Disease Models, Animal Antibodies  >3 publications with PSMB9 and Disease Models, Animal
 Adenocarcinoma Antibodies  >2 publications with PSMB9 and Adenocarcinoma
 Necrosis Antibodies  >2 publications with PSMB9 and Necrosis
 Infertility, Male Antibodies  >1 publications with PSMB9 and Infertility, Male
 Cell Transformation, Neoplastic Antibodies  >1 publications with PSMB9 and Cell Transformation, Neoplastic
 Liver Diseases Antibodies  >1 publications with PSMB9 and Liver Diseases
 Fibrosis Antibodies  >1 publications with PSMB9 and Fibrosis
 Brain Diseases Antibodies  >1 publications with PSMB9 and Brain Diseases
Organs/Tissues associated with PSMB9 peptide
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with PSMB9 and Blood
 Kidney Antibodies  >7 publications with PSMB9 and Kidney
 Brain Antibodies  >4 publications with PSMB9 and Brain
 Spleen Antibodies  >3 publications with PSMB9 and Spleen
 Liver Antibodies  >3 publications with PSMB9 and Liver
 Muscle Antibodies  >3 publications with PSMB9 and Muscle
 Lung Antibodies  >3 publications with PSMB9 and Lung
 Skin Antibodies  >2 publications with PSMB9 and Skin
 Salivary Gland Antibodies  >1 publications with PSMB9 and Salivary Gland
 Nerve Antibodies  >1 publications with PSMB9 and Nerve
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