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PALLD peptide :: Palladin Peptide

Scan QR to view Datasheet Catalog #    MBS426674 PALLD peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Palladin (PALLD), Peptide

 Also Known As   

Palladin Immunizing Peptide

 Product Synonym Names    PALLD; palladin, cytoskeletal associated protein; CGI-151; FLJ22190; FLJ38193; FLJ39139; KIAA0992; PNCA1; SIH002; palladin; sarcoma antigen NY-SAR-77; Palladin; Palladin (aa895-907)
 Product Gene Name   

PALLD peptide

[Similar Products]
 Antibody/Peptide Pairs    Palladin peptide (MBS426674) is used for blocking the activity of Palladin antibody (MBS421830)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-RDSGDENE PIQER
 OMIM    606856
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 Species Reactivity    Human, Mouse, Rat, Dog
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of PALLD peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for PALLD. It may not necessarily be applicable to this product.
 NCBI GI #    93102361
 NCBI GeneID    23022
 NCBI Accession #    NP_057165.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_016081.3 [Other Products]
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 UniProt Secondary Accession #    Q7L3E0; Q7Z3W0; Q86WE8; Q8N1M2; Q9UGA0; Q9UQF5; Q9Y2J6; Q9Y3E9; B3KTG2; B5MD56; B7ZMM5 [Other Products]
 UniProt Related Accession #    Q8WX93 [Other Products]
 Molecular Weight    123,693 Da
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 NCBI Official Full Name    palladin isoform 2
 NCBI Official Synonym Full Names    palladin, cytoskeletal associated protein
 NCBI Official Symbol    PALLD [Similar Products]
 NCBI Official Synonym Symbols   
MYN; PNCA1; CGI151; SIH002; CGI-151
[Similar Products]
 NCBI Protein Information    palladin
 UniProt Protein Name    Palladin
 UniProt Synonym Protein Names   
SIH002; Sarcoma antigen NY-SAR-77
 Protein Family    Palladin
 UniProt Gene Name    PALLD [Similar Products]
 UniProt Synonym Gene Names    KIAA0992 [Similar Products]
 UniProt Entry Name    PALLD_HUMAN
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 NCBI Summary for PALLD    This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
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 UniProt Comments for PALLD    palladin: Cytoskeletal protein required for organization of normal actin cytoskeleton. Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays. Binds to proteins that bind to either monomeric or filamentous actin. Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Different isoforms may have functional differences. Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation. Involved in targeting ACTN to specific subcellular foci. Genetic variations in PALLD are associated with susceptibility to pancreatic cancer type 1 (PNCA1). Expression is increased early in the development of pancreatic cancer: in normal-appearing whole tissue immediately adjacent to cancer, in the pre-cancer, and in both the familial and sporadic forms of the cancer. Genetic variations in PALLD may be associated with myocardial infarction. Belongs to the myotilin/palladin family. 9 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 4q32.3

Cellular Component: actin cytoskeleton; actin filament; axon; cytoplasm; focal adhesion; growth cone; lamellipodium; mitochondrion; nucleus; plasma membrane; podosome; ruffle; Z disc

Molecular Function: actin binding; muscle alpha-actinin binding; protein binding

Biological Process: actin cytoskeleton organization and biogenesis; cell migration; cytoskeleton organization and biogenesis

Disease: Pancreatic Cancer, Susceptibility To, 1
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 Research Articles on PALLD    1. Study identified the actin-associated protein palladin as a key node in signaling pathways that result in fibroblast activation in the increased tissue stiffness of a tumor microenvironment
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with PALLD peptideOrgans/Tissues associated with PALLD peptide
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >6 publications with PALLD and Cardiovascular Diseases
 Pancreatic Neoplasms Antibodies  >6 publications with PALLD and Pancreatic Neoplasms
 Nervous System Diseases Antibodies  >4 publications with PALLD and Nervous System Diseases
 Heart Diseases Antibodies  >4 publications with PALLD and Heart Diseases
 Liver Diseases Antibodies  >2 publications with PALLD and Liver Diseases
 Hypertension Antibodies  >2 publications with PALLD and Hypertension
 Heart Failure Antibodies  >1 publications with PALLD and Heart Failure
 Fatty Liver Antibodies  >1 publications with PALLD and Fatty Liver
 Neoplasms, Experimental Antibodies  >1 publications with PALLD and Neoplasms, Experimental
 Inflammation Antibodies  >1 publications with PALLD and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with PALLD and Blood
 Liver Antibodies  >3 publications with PALLD and Liver
 Heart Antibodies  >3 publications with PALLD and Heart
 Vascular Antibodies  >2 publications with PALLD and Vascular
 Testis Antibodies  >2 publications with PALLD and Testis
 Lung Antibodies  >2 publications with PALLD and Lung
 Pancreas Antibodies  >1 publications with PALLD and Pancreas
 Prostate Antibodies  >1 publications with PALLD and Prostate
 Skin Antibodies  >1 publications with PALLD and Skin
 Connective Tissue Antibodies  >1 publications with PALLD and Connective Tissue
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