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RAB11A peptide :: RAB11A / YL8 Peptide

Scan QR to view Datasheet Catalog #    MBS425588 RAB11A peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RAB11A / YL8, Peptide

 Also Known As   

RAB11A / YL8 Immunizing Peptide

 Product Synonym Names    RAB11A; YL8; RAB11A, member RAS oncogene family; RAB 11A, member oncogene family; MGC1490; Ras-related protein Rab-11A; RAB11A / YL8
 Product Gene Name   

RAB11A peptide

[Similar Products]
 Product Synonym Gene Name    YL8 [Similar Products]
 Antibody/Peptide Pairs    RAB11A / YL8 peptide (MBS425588) is used for blocking the activity of RAB11A/YL8 antibody (MBS420889)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    TENKPKVQCC QNI
 OMIM    605570
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 Species Reactivity    Human, Mouse, Rat, Cow
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of RAB11A peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for RAB11A. It may not necessarily be applicable to this product.
 NCBI GI #    4758984
 NCBI GeneID    8766
 NCBI Accession #    NP_004654.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004663.4 [Other Products]
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 UniProt Secondary Accession #    P24410; Q5TZN9; Q9JLX1; B2R4B6; B4DT13 [Other Products]
 UniProt Related Accession #    P62491 [Other Products]
 Molecular Weight    17,659 Da
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 NCBI Official Full Name    ras-related protein Rab-11A isoform 1
 NCBI Official Synonym Full Names    RAB11A, member RAS oncogene family
 NCBI Official Symbol    RAB11A [Similar Products]
 NCBI Official Synonym Symbols   
YL8
[Similar Products]
 NCBI Protein Information    ras-related protein Rab-11A
 UniProt Protein Name    Ras-related protein Rab-11A
 UniProt Synonym Protein Names   
YL8
 Protein Family    Ras-related protein
 UniProt Gene Name    RAB11A [Similar Products]
 UniProt Synonym Gene Names    RAB11; Rab-11 [Similar Products]
 UniProt Entry Name    RB11A_HUMAN
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 NCBI Summary for RAB11A    The protein encoded by this gene belongs to the Rab family of the small GTPase superfamily. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
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 UniProt Comments for RAB11A    RAB11A: Regulates endocytic recycling. May exert its functions by interacting with multiple effector proteins in different complexes. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells. Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane. Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes. Interacts with RIP11 and STXBP6. Interacts with SGSM1, SGSM2 and SGSM3. Interacts with EXOC6 in a GTP- dependent manner. Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 (via its C-terminus) and RAB11FIP4. Interacts with EVI5; EVI5 and RAB11FIP3 may be mutually exclusive and compete for binding RAB11A. Interacts with SPE39//C14orf133. Interacts with MYO5B. Found in a complex with MYO5B and CFTR. Interacts with NPC1L1. Interacts (GDP-bound form) with ZFYVE27. Interacts with BIRC6/bruce. Belongs to the small GTPase superfamily. Rab family.

Protein type: Motility/polarity/chemotaxis; G protein, monomeric, Rab; G protein; G protein, monomeric

Chromosomal Location of Human Ortholog: 15q22.31

Cellular Component: axon; centrosome; cleavage furrow; cytoplasmic vesicle; cytoplasmic vesicle membrane; cytosol; Golgi apparatus; kinetochore microtubule; mitochondrion; multivesicular body; perinuclear region of cytoplasm; phagocytic vesicle; plasma membrane; protein complex; recycling endosome; recycling endosome membrane; spindle pole; trans-Golgi network; transport vesicle; vesicle

Molecular Function: GTP binding; GTPase activity; microtubule binding; myosin V binding; protein binding; syntaxin binding

Biological Process: astral microtubule organization and biogenesis; cytokinesis; establishment of vesicle localization; intracellular protein transport; melanosome transport; metabolic process; mitotic metaphase plate congression; neurite development; nucleocytoplasmic transport; plasma membrane to endosome transport; positive regulation of axon extension; regulation of long-term neuronal synaptic plasticity; regulation of protein transport; renal water homeostasis; small GTPase mediated signal transduction; vesicle-mediated transport
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 Research Articles on RAB11A    1. Authors show that Rab11-GMPPNP-FIP3-Rabin8 is more stable than Rab11-GMPPNP-Rabin8, owing to direct interaction between Rabin8 and FIP3 within the dual effector-bound complex.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with RAB11A peptidePathways associated with RAB11A peptide
 Reference Product  PubMed Publications
 MYO5B peptide  >21 publications with RAB11A and MYO5B
 RAB3IP peptide  >2 publications with RAB11A and RAB3IP
 RAB11FIP5 peptide  >2 publications with RAB11A and RAB11FIP5
 RAB11FIP3 peptide  >1 publications with RAB11A and RAB11FIP3
 Products by Pathway  Pathway Diagram
 Anchoring Of The Basal Body To The Plasma Membrane Pathway antibodies  Anchoring Of The Basal Body To The Plasma Membrane Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Arf6 Downstream Pathway antibodies  Arf6 Downstream Pathway Diagram
 Assembly Of The Primary Cilium Pathway antibodies  Assembly Of The Primary Cilium Pathway Diagram
 Cargo Trafficking To The Periciliary Membrane Pathway antibodies  Cargo Trafficking To The Periciliary Membrane Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Endocrine And Other Factor-regulated Calcium Reabsorption Pathway antibodies  Endocrine And Other Factor-regulated Calcium Reabsorption Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
Diseases associated with RAB11A peptideOrgans/Tissues associated with RAB11A peptide
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >8 publications with RAB11A and Nervous System Diseases
 Inflammation Antibodies  >8 publications with RAB11A and Inflammation
 Adenocarcinoma Antibodies  >5 publications with RAB11A and Adenocarcinoma
 Fibrosis Antibodies  >5 publications with RAB11A and Fibrosis
 Kidney Diseases Antibodies  >3 publications with RAB11A and Kidney Diseases
 Atrophy Antibodies  >3 publications with RAB11A and Atrophy
 Liver Diseases Antibodies  >2 publications with RAB11A and Liver Diseases
 Necrosis Antibodies  >2 publications with RAB11A and Necrosis
 Urinary Bladder Neoplasms Antibodies  >1 publications with RAB11A and Urinary Bladder Neoplasms
 Cardiovascular Diseases Antibodies  >1 publications with RAB11A and Cardiovascular Diseases
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >33 publications with RAB11A and Kidney
 Brain Antibodies  >16 publications with RAB11A and Brain
 Liver Antibodies  >14 publications with RAB11A and Liver
 Intestine Antibodies  >13 publications with RAB11A and Intestine
 Blood Antibodies  >13 publications with RAB11A and Blood
 Muscle Antibodies  >10 publications with RAB11A and Muscle
 Vascular Antibodies  >8 publications with RAB11A and Vascular
 Nerve Antibodies  >7 publications with RAB11A and Nerve
 Stomach Antibodies  >7 publications with RAB11A and Stomach
 Heart Antibodies  >7 publications with RAB11A and Heart
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