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IPO7 peptide :: RANBP7 / Importin 7 Peptide

Scan QR to view Datasheet Catalog #    MBS426840 IPO7 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RANBP7 / Importin 7 (IPO7), Peptide

 Also Known As   

RANBP7 / Importin 7 Immunizing Peptide

 Product Synonym Names    IPO7; importin 7; RANBP7; FLJ14581; MGC138673; RAN binding protein 7; RAN-binding protein 7; Importin 7; RANBP7 / Importin 7
 Product Gene Name   

IPO7 peptide

[Similar Products]
 Product Synonym Gene Name    RANBP7 [Similar Products]
 Antibody/Peptide Pairs    RANBP7 / Importin 7 peptide (MBS426840) is used for blocking the activity of RANBP7/Importin 7 antibody (MBS421213)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-SSFNFGGP APGMN
 OMIM    605586
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 Species Reactivity    Human, Mouse, Rat, Dog, Cow
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of IPO7 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for IPO7. It may not necessarily be applicable to this product.
 NCBI GI #    5453998
 NCBI GeneID    10527
 NCBI Accession #    NP_006382.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006391.2 [Other Products]
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 UniProt Secondary Accession #    Q1RMF7; Q9H177; Q9NTE3; A6NNM5; B2R786 [Other Products]
 UniProt Related Accession #    O95373 [Other Products]
 Molecular Weight    119,517 Da
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 NCBI Official Full Name    importin-7
 NCBI Official Synonym Full Names    importin 7
 NCBI Official Symbol    IPO7 [Similar Products]
 NCBI Official Synonym Symbols   
Imp7; RANBP7
[Similar Products]
 NCBI Protein Information    importin-7
 UniProt Protein Name    Importin-7
 UniProt Synonym Protein Names   
Ran-binding protein 7; RanBP7
 Protein Family    Importin
 UniProt Gene Name    IPO7 [Similar Products]
 UniProt Synonym Gene Names    RANBP7; Imp7; RanBP7 [Similar Products]
 UniProt Entry Name    IPO7_HUMAN
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 NCBI Summary for IPO7    The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IPO7    IPO7: a beta importin protein. Functions in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin beta-1 subunit. A receptor for nuclear localization signals (NLS) that promotes translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.

Protein type: Nuclear import; Karyopherin; Nuclear export

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: cytoplasm; cytosol; membrane; nuclear pore; nucleoplasm

Molecular Function: GTPase regulator activity; histone binding; protein binding; protein transporter activity; Ran GTPase binding; transporter activity

Biological Process: innate immune response; protein import into nucleus; regulation of catalytic activity; signal transduction; viral reproduction
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 Research Articles on IPO7    1. Depletion of IPO7 by IPO7 siRNA reduced nuclear accumulation of GLI1. In addition, FOXM1 induced nuclear import of GLI1 by promoting IPO7 expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IPO7 peptideDiseases associated with IPO7 peptide
 Reference Product  PubMed Publications
 RAN peptide  >10 publications with IPO7 and RAN
 SMAD2 peptide  >3 publications with IPO7 and SMAD2
 EGR1 peptide  >2 publications with IPO7 and EGR1
 IPO5 peptide  >2 publications with IPO7 and IPO5
 RPL23A peptide  >1 publications with IPO7 and RPL23A
 KPNB1 peptide  >1 publications with IPO7 and KPNB1
 Disease Name  Pubmed Publications
 Prostatic Neoplasms Antibodies  >3 publications with IPO7 and Prostatic Neoplasms
 HIV Infections Antibodies  >2 publications with IPO7 and HIV Infections
 Cardiovascular Diseases Antibodies  >1 publications with IPO7 and Cardiovascular Diseases
 Fibrosis Antibodies  >1 publications with IPO7 and Fibrosis
 Kidney Diseases Antibodies  >1 publications with IPO7 and Kidney Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with IPO7 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with IPO7 and Liver Neoplasms
 Cell Transformation, Neoplastic Antibodies  >1 publications with IPO7 and Cell Transformation, Neoplastic
 Adenocarcinoma Antibodies  >1 publications with IPO7 and Adenocarcinoma
 Liver Diseases Antibodies  >1 publications with IPO7 and Liver Diseases
Organs/Tissues associated with IPO7 peptide
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with IPO7 and Blood
 Prostate Antibodies  >3 publications with IPO7 and Prostate
 Vascular Antibodies  >2 publications with IPO7 and Vascular
 Lung Antibodies  >2 publications with IPO7 and Lung
 Liver Antibodies  >1 publications with IPO7 and Liver
 Bone Antibodies  >1 publications with IPO7 and Bone
 Muscle Antibodies  >1 publications with IPO7 and Muscle
 Ovary Antibodies  >1 publications with IPO7 and Ovary
 Kidney Antibodies  >1 publications with IPO7 and Kidney
 Eye Antibodies  >1 publications with IPO7 and Eye
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