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RASSF6 peptide

Scan QR to view Datasheet Catalog #    MBS426247 RASSF6 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RASSF6, Peptide

 Also Known As   

RASSF6 Immunizing Peptide

 Product Synonym Names    RASSF6; Ras association (RalGDS/AF-6) domain family 6; DKFZp686K23225; putative RAS binding protein
 Product Gene Name   

RASSF6 peptide

[Similar Products]
 Antibody/Peptide Pairs    RASSF6 peptide (MBS426247) is used for blocking the activity of RASSF6 antibody (MBS421614)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-SNTLKPHA KDEPDS
 OMIM    612620
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of RASSF6 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for RASSF6. It may not necessarily be applicable to this product.
 NCBI GI #    29789443
 NCBI GeneID    166824
 NCBI Accession #    NP_803876.1 [Other Products]
 NCBI Related Accession #    NP_958834.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_177532.4 [Other Products]
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 UniProt Secondary Accession #    Q68DT2; Q6PDA6; Q86WG9; Q86WH0 [Other Products]
 UniProt Related Accession #    Q6ZTQ3 [Other Products]
 Molecular Weight    35,809 Da
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 NCBI Official Full Name    ras association domain-containing protein 6 isoform a
 NCBI Official Synonym Full Names    Ras association domain family member 6
 NCBI Official Symbol    RASSF6 [Similar Products]
 NCBI Protein Information    ras association domain-containing protein 6
 UniProt Protein Name    Ras association domain-containing protein 6
 Protein Family    Ras association domain-containing protein
 UniProt Gene Name    RASSF6 [Similar Products]
 UniProt Entry Name    RASF6_HUMAN
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 NCBI Summary for RASSF6    This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]
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 UniProt Comments for RASSF6    RASSF6: Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 4q13.3

Molecular Function: protein binding

Biological Process: apoptosis; signal transduction
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 Research Articles on RASSF6    1. Mechanistic investigation shows that RASSF6 triggers p21(Cip1/Waf1) accumulation to induce G 1 cell cycle arrest and promote apoptosis upon exposure to pro-apoptotic agents, and both of these mechanisms appear to be mediated by activated JNK signaling.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with RASSF6 peptideDiseases associated with RASSF6 peptide
 Products by Pathway  Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >5 publications with RASSF6 and Adenocarcinoma
 Lung Diseases Antibodies  >3 publications with RASSF6 and Lung Diseases
 Cell Transformation, Neoplastic Antibodies  >3 publications with RASSF6 and Cell Transformation, Neoplastic
 Neoplasm Metastasis Antibodies  >2 publications with RASSF6 and Neoplasm Metastasis
 Neoplasms, Experimental Antibodies  >2 publications with RASSF6 and Neoplasms, Experimental
 Inflammation Antibodies  >2 publications with RASSF6 and Inflammation
 Breast Neoplasms Antibodies  >2 publications with RASSF6 and Breast Neoplasms
 Kidney Diseases Antibodies  >1 publications with RASSF6 and Kidney Diseases
 Nervous System Diseases Antibodies  >1 publications with RASSF6 and Nervous System Diseases
 Lung Neoplasms Antibodies  >1 publications with RASSF6 and Lung Neoplasms
Organs/Tissues associated with RASSF6 peptide
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with RASSF6 and Brain
 Kidney Antibodies  >2 publications with RASSF6 and Kidney
 Bladder Antibodies  >1 publications with RASSF6 and Bladder
 Stomach Antibodies  >1 publications with RASSF6 and Stomach
 Liver Antibodies  >1 publications with RASSF6 and Liver
 Lymph Node Antibodies  >1 publications with RASSF6 and Lymph Node
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