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Rassf1 peptide

Scan QR to view Datasheet Catalog #    MBS425237 Rassf1 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Rassf1, Peptide

 Also Known As   

Rassf1 Immunizing Peptide

 Product Synonym Names    RASSF1; Ras association (RalGDS/AF-6) domain family 1; AA536941; AU044980; NORE2A; RDA32; REH3P21; Rassf1A; Rassf1B; Rassf1C; 123F protein; Rassf1 (mouse)
 Product Gene Name   

Rassf1 peptide

[Similar Products]
 Antibody/Peptide Pairs    Rassf1 peptide (MBS425237) is used for blocking the activity of Rassf1 antibody (MBS421391)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-QAETEQKI KDYNGQ
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 Species Reactivity    Mouse, Rat
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of Rassf1 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for Rassf1. It may not necessarily be applicable to this product.
 NCBI GI #    9790187
 NCBI GeneID    56289
 NCBI Accession #    NP_062687.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_019713.4 [Other Products]
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 UniProt Secondary Accession #    Q9WUF5 [Other Products]
 UniProt Related Accession #    Q99MK9 [Other Products]
 Molecular Weight    31,193 Da
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 NCBI Official Full Name    ras association domain-containing protein 1 isoform 2
 NCBI Official Synonym Full Names    Ras association (RalGDS/AF-6) domain family member 1
 NCBI Official Symbol    Rassf1 [Similar Products]
 NCBI Official Synonym Symbols   
123F2; RDA32; NORE2A; REH3P21; Rassf1A; Rassf1B; Rassf1C; AA536941; AU044980
[Similar Products]
 NCBI Protein Information    ras association domain-containing protein 1
 UniProt Protein Name    Ras association domain-containing protein 1
 UniProt Synonym Protein Names   
Protein 123F2
 Protein Family    Ras association domain-containing protein
 UniProt Gene Name    Rassf1 [Similar Products]
 UniProt Entry Name    RASF1_MOUSE
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 UniProt Comments for Rassf1    RASSF1: Potential tumor suppressor. Required for death receptor- dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression. Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein. Isoform C has been shown not to perform these roles, no function has been identified for this isoform. Isoform A disrupts interactions among MDM2, DAXX and USP7, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage. Interacts with MAP1S and XPA. Binds to the N-terminal of CDC20 during prometaphase. Binds to STK3/MST2 and STK4/MST1. Isoform A interacts with MOAP1 and E4F1. Recruited to the TNFRSF1A and TNFRSF10A complexes in response to their respective cognate ligand, after internalization. Can self-associate. Isoform A interacts with RSSF5 and probably associates with HRAS1 via a RSSF1 isoform A-RSSF5 heterodimer. Part of a complex with MDM2, DAXX, RASSF1 and USP7. Isoform A interacts (via C-terminus) with DAXX (via N-terminus); the interaction is independent of MDM2 and TP53. Isoform C or isoform H interacts (via N-terminus) with DAXX. Isoform A interacts (via N-terminus) with MDM2 (via C-terminus); the interaction is independent of TP53. Isoform A and isoform C are ubiquitously expressed in all tissues tested, however isoform A is absent in many corresponding cancer cell lines. Isoform B is mainly expressed in hematopoietic cells. 8 isoforms of the human protein are produced by alternative promoter.

Protein type: Tumor suppressor

Cellular Component: cytoplasm; cytoskeleton; microtubule; microtubule cytoskeleton; nucleus; plasma membrane

Molecular Function: identical protein binding; metal ion binding; protein binding; protein N-terminus binding

Biological Process: cell cycle; cell cycle arrest; positive regulation of protein ubiquitination; protein stabilization; Ras protein signal transduction; response to DNA damage stimulus; signal transduction
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 Research Articles on Rassf1    1. essential role of RASSF1A in regulating TNF-alpha signalling in cardiomyocytes, with RASSF1A being key in the formation of the TNFR complex and in signal transmission to the downstream targets
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Rassf1 peptidePathways associated with Rassf1 peptide
 Reference Product  PubMed Publications
 Cdkn2a peptide  >215 publications with Rassf1 and Cdkn2a
 Kras peptide  >28 publications with Rassf1 and Kras
 Stk4 peptide  >16 publications with Rassf1 and Stk4
 Stk3 peptide  >14 publications with Rassf1 and Stk3
 Cdc20 peptide  >10 publications with Rassf1 and Cdc20
 Daxx peptide  >6 publications with Rassf1 and Daxx
 Nras peptide  >5 publications with Rassf1 and Nras
 Aurka peptide  >4 publications with Rassf1 and Aurka
 Btrc peptide  >1 publications with Rassf1 and Btrc
 Products by Pathway  Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 Non-small Cell Lung Cancer Pathway antibodies  Non-small Cell Lung Cancer Pathway Diagram
 Non-small Cell Lung Cancer Pathway antibodies  Non-small Cell Lung Cancer Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Ras Signaling Pathway antibodies  Ras Signaling Pathway Diagram
Diseases associated with Rassf1 peptideOrgans/Tissues associated with Rassf1 peptide
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >401 publications with Rassf1 and Carcinoma
 Adenocarcinoma Antibodies  >205 publications with Rassf1 and Adenocarcinoma
 Lung Neoplasms Antibodies  >200 publications with Rassf1 and Lung Neoplasms
 Breast Neoplasms Antibodies  >155 publications with Rassf1 and Breast Neoplasms
 Lung Diseases Antibodies  >151 publications with Rassf1 and Lung Diseases
 Carcinoma, Non-Small-Cell Lung Antibodies  >87 publications with Rassf1 and Carcinoma, Non-Small-Cell Lung
 Neoplasms, Experimental Antibodies  >73 publications with Rassf1 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >67 publications with Rassf1 and Liver Neoplasms
 Liver Diseases Antibodies  >60 publications with Rassf1 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >54 publications with Rassf1 and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >216 publications with Rassf1 and Lung
 Liver Antibodies  >75 publications with Rassf1 and Liver
 Kidney Antibodies  >47 publications with Rassf1 and Kidney
 Brain Antibodies  >32 publications with Rassf1 and Brain
 Bladder Antibodies  >32 publications with Rassf1 and Bladder
 Stomach Antibodies  >27 publications with Rassf1 and Stomach
 Thyroid Antibodies  >21 publications with Rassf1 and Thyroid
 Skin Antibodies  >19 publications with Rassf1 and Skin
 Heart Antibodies  >11 publications with Rassf1 and Heart
 Pancreas Antibodies  >8 publications with Rassf1 and Pancreas
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