NP_149094.3
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
59,998 Da
NCBI Official Full Name
rhophilin-2
NCBI Official Synonym Full Names
rhophilin, Rho GTPase binding protein 2
NCBI Protein Information
rhophilin-2
UniProt Protein Name
Rhophilin-2
UniProt Synonym Protein Names
76 kDa RhoB effector protein; GTP-Rho-binding protein 2; p76RBE
UniProt Entry Name
RHPN2_HUMAN
NCBI Summary for RHPN2
This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009]
UniProt Comments for RHPN2
RHPN2: Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity. Belongs to the RHPN family.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 19q13.11
Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; nucleoplasm; perinuclear region of cytoplasm
Biological Process: signal transduction
Research Articles on RHPN2
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Products associated with RHPN2 blocking peptide
Pathways associated with RHPN2 blocking peptide
Diseases associated with RHPN2 blocking peptide
Organs/Tissues associated with RHPN2 blocking peptide
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