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SON peptide

Scan QR to view Datasheet Catalog #    MBS427489 SON peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SON, Peptide

 Also Known As   

SON Immunizing Peptide

 Product Synonym Names    SON; SON DNA binding protein; BASS1; C21orf50; DBP-5; FLJ21099; FLJ33914; KIAA1019; NREBP; SON3; Bax antagonist selected in Saccharomyces 1; NRE-binding protein; OTTHUMP00000197908; OTTHUMP00000198934; negative regulatory element-binding protein; protein
 Product Gene Name   

SON peptide

[Similar Products]
 Antibody/Peptide Pairs    SON peptide (MBS427489) is used for blocking the activity of SON antibody (MBS422618)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    KSRCVSVQTD PTD
 OMIM    182465
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 Species Reactivity    Human, Mouse, Rat, Dog, Cow
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of SON peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for SON. It may not necessarily be applicable to this product.
 NCBI GI #    21040314
 NCBI GeneID    6651
 NCBI Accession #    NP_115571.1 [Other Products]
 NCBI Related Accession #    NP_620305.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_032195.1 [Other Products]
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 UniProt Secondary Accession #    O14487; O95981; Q14120; Q6PKE0; Q9H7B1; D3DSF5; D3DSF6; E7ETE8; E7EU67; E7EVW3; E9PFQ2 [Other Products]
 UniProt Related Accession #    P18583 [Other Products]
 Molecular Weight    247,823 Da
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 NCBI Official Full Name    protein SON isoform B
 NCBI Official Synonym Full Names    SON DNA binding protein
 NCBI Official Symbol    SON [Similar Products]
 NCBI Official Synonym Symbols   
SON3; BASS1; DBP-5; NREBP; C21orf50
[Similar Products]
 NCBI Protein Information    protein SON
 UniProt Protein Name    Protein SON
 UniProt Synonym Protein Names   
Bax antagonist selected in saccharomyces 1; BASS1; Negative regulatory element-binding protein; NRE-binding protein; Protein DBP-5; SON3
 Protein Family    Son of sevenless
 UniProt Gene Name    SON [Similar Products]
 UniProt Synonym Gene Names    C21orf50; DBP5; KIAA1019; NREBP; BASS1; NRE-binding protein [Similar Products]
 UniProt Entry Name    SON_HUMAN
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 NCBI Summary for SON    This gene encodes a protein that contains multiple simple repeats. The encoded protein binds RNA and promotes pre-mRNA splicing, particularly of transcripts with poor splice sites. The protein also recognizes a specific DNA sequence found in the human hepatitis B virus (HBV) and represses HBV core promoter activity. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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 UniProt Comments for SON    SON: RNA-binding protein that acts as a mRNA splicing cofactor by promoting efficient splicing of transcripts that posses weak splice sites. Specifically promotes splicing of many cell-cycle and DNA-repair transcripts that posses weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG. Probably acts by facilitating the interaction between Serine/arginine-rich proteins such as SRSF2 and the RNA polymerase II. Also binds to DNA; binds to the consensus DNA sequence: 5'- GA[GT]AN[CG][AG]CC-3'. May indirectly repress hepatitis B virus (HBV) core promoter activity and transcription of HBV genes and production of HBV virions. 10 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; RNA-binding

Chromosomal Location of Human Ortholog: 21q22.11

Cellular Component: nuclear speck; nucleoplasm

Molecular Function: DNA binding; nucleic acid binding; protein binding; RNA binding; RS domain binding

Biological Process: cytokinesis; microtubule cytoskeleton organization and biogenesis; mRNA processing; negative regulation of apoptosis; regulation of cell cycle; regulation of RNA splicing; RNA splicing
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 Research Articles on SON    1. Here, we summarize available information from several early studies on SON, and highlight recent discoveries describing molecular mechanisms of SON-mediated gene regulation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SON peptideDiseases associated with SON peptide
 Reference Product  PubMed Publications
 UBC peptide  >2 publications with SON and UBC
 TFPI peptide  >2 publications with SON and TFPI
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2171 publications with SON and Nervous System Diseases
 Brain Diseases Antibodies  >997 publications with SON and Brain Diseases
 Heart Diseases Antibodies  >682 publications with SON and Heart Diseases
 Inflammation Antibodies  >541 publications with SON and Inflammation
 Disease Models, Animal Antibodies  >413 publications with SON and Disease Models, Animal
 Liver Diseases Antibodies  >400 publications with SON and Liver Diseases
 Kidney Diseases Antibodies  >385 publications with SON and Kidney Diseases
 Necrosis Antibodies  >375 publications with SON and Necrosis
 Adenocarcinoma Antibodies  >340 publications with SON and Adenocarcinoma
 Breast Neoplasms Antibodies  >289 publications with SON and Breast Neoplasms
Organs/Tissues associated with SON peptide
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3032 publications with SON and Blood
 Brain Antibodies  >2799 publications with SON and Brain
 Bone Antibodies  >897 publications with SON and Bone
 Vascular Antibodies  >876 publications with SON and Vascular
 Heart Antibodies  >794 publications with SON and Heart
 Liver Antibodies  >771 publications with SON and Liver
 Skin Antibodies  >748 publications with SON and Skin
 Muscle Antibodies  >731 publications with SON and Muscle
 Nerve Antibodies  >704 publications with SON and Nerve
 Kidney Antibodies  >624 publications with SON and Kidney
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