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PLK4 peptide :: Sak / STK18 / PLK4 Peptide

Scan QR to view Datasheet Catalog #    MBS426562 PLK4 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Sak / STK18 / PLK4, Peptide

 Also Known As   

Sak / STK18 / PLK4 Immunizing Peptide

 Product Synonym Names    PLK4; Sak; polo-like kinase 4 (Drosophila); serine/threonine kinase 18; SAK; Snk Akin Kinase; polo-like kinase 4; protein-serine/threonine kinase; STK18; serine/threonine protein kinase SAK; Sak / STK18 / PLK4
 Product Gene Name   

PLK4 peptide

[Similar Products]
 Product Synonym Gene Name    Sak; STK18 [Similar Products]
 Antibody/Peptide Pairs    Sak / STK18 / PLK4 peptide (MBS426562) is used for blocking the activity of Sak/STK18/PLK4 antibody (MBS420966)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    ATCIGEKIED FKVGN
 OMIM    605031
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 Species Reactivity    Human, Dog, Cow
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of PLK4 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for PLK4. It may not necessarily be applicable to this product.
 NCBI GI #    121114283
 NCBI GeneID    10733
 NCBI Accession #    NP_055079.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_014264.4 [Other Products]
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 UniProt Secondary Accession #    Q8IYF0; Q96Q95; Q9UD84; Q9UDE2; B2RAL0; B7Z837; B7Z8G7 [Other Products]
 UniProt Related Accession #    O00444 [Other Products]
 Molecular Weight    104,636 Da
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 NCBI Official Full Name    serine/threonine-protein kinase PLK4 isoform 1
 NCBI Official Synonym Full Names    polo like kinase 4
 NCBI Official Symbol    PLK4 [Similar Products]
 NCBI Official Synonym Symbols   
SAK; STK18; MCCRP2
[Similar Products]
 NCBI Protein Information    serine/threonine-protein kinase PLK4
 UniProt Protein Name    Serine/threonine-protein kinase PLK4
 UniProt Synonym Protein Names   
Polo-like kinase 4; PLK-4; Serine/threonine-protein kinase 18; Serine/threonine-protein kinase Sak
 UniProt Gene Name    PLK4 [Similar Products]
 UniProt Synonym Gene Names    SAK; STK18; PLK-4 [Similar Products]
 UniProt Entry Name    PLK4_HUMAN
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 NCBI Summary for PLK4    This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
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 UniProt Comments for PLK4    PLK4: a kinase of the PLK family. Localizes to centrosomes and the cleavage furrow during cytokinesis. Interacts with the protein kinase Tec.

Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.21; Nucleolus; Protein kinase, Other; Other group; PLK family

Chromosomal Location of Human Ortholog: 4q28

Cellular Component: centriole; centrosome; cleavage furrow; cytosol; nucleolus; XY body

Molecular Function: ATP binding; identical protein binding; protein binding; protein serine/threonine kinase activity

Biological Process: centriole replication; G2/M transition of mitotic cell cycle; positive regulation of centriole replication; protein amino acid phosphorylation

Disease: Microcephaly And Chorioretinopathy, Autosomal Recessive, 2
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 Research Articles on PLK4    1. Decreased PLK4 protein expression due to promoter hypermethylation was negatively correlated with JAK2 overexpression, a common occurrence in hematological malignancies.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PLK4 peptidePathways associated with PLK4 peptide
 Reference Product  PubMed Publications
 CEP152 peptide  >20 publications with PLK4 and CEP152
 CEP135 peptide  >11 publications with PLK4 and CEP135
 CEP192 peptide  >10 publications with PLK4 and CEP192
 CENPJ peptide  >8 publications with PLK4 and CENPJ
 CDC25C peptide  >4 publications with PLK4 and CDC25C
 CCP110 peptide  >4 publications with PLK4 and CCP110
 PCNT peptide  >1 publications with PLK4 and PCNT
 CDK5RAP2 peptide  >1 publications with PLK4 and CDK5RAP2
 TUBG1 peptide  >1 publications with PLK4 and TUBG1
 Products by Pathway  Pathway Diagram
 AURKA Activation By TPX2 Pathway antibodies  AURKA Activation By TPX2 Pathway Diagram
 Anchoring Of The Basal Body To The Plasma Membrane Pathway antibodies  Anchoring Of The Basal Body To The Plasma Membrane Pathway Diagram
 Assembly Of The Primary Cilium Pathway antibodies  Assembly Of The Primary Cilium Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Centrosome Maturation Pathway antibodies  Centrosome Maturation Pathway Diagram
 FoxO Signaling Pathway antibodies  FoxO Signaling Pathway Diagram
 G2/M Transition Pathway antibodies  G2/M Transition Pathway Diagram
 Loss Of Nlp From Mitotic Centrosomes Pathway antibodies  Loss Of Nlp From Mitotic Centrosomes Pathway Diagram
 Loss Of Proteins Required For Interphase Microtubule Organizationfrom The Centrosome Pathway antibodies  Loss Of Proteins Required For Interphase Microtubule Organizationfrom The Centrosome Pathway Diagram
Diseases associated with PLK4 peptideOrgans/Tissues associated with PLK4 peptide
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >11 publications with PLK4 and Breast Neoplasms
 Microcephaly Antibodies  >11 publications with PLK4 and Microcephaly
 Nervous System Diseases Antibodies  >9 publications with PLK4 and Nervous System Diseases
 Liver Neoplasms Antibodies  >7 publications with PLK4 and Liver Neoplasms
 Cell Transformation, Neoplastic Antibodies  >5 publications with PLK4 and Cell Transformation, Neoplastic
 Dwarfism Antibodies  >5 publications with PLK4 and Dwarfism
 Kidney Diseases Antibodies  >4 publications with PLK4 and Kidney Diseases
 Carcinoma, Hepatocellular Antibodies  >4 publications with PLK4 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >4 publications with PLK4 and Liver Diseases
 Inflammation Antibodies  >3 publications with PLK4 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >7 publications with PLK4 and Lung
 Kidney Antibodies  >7 publications with PLK4 and Kidney
 Embryonic Tissue Antibodies  >6 publications with PLK4 and Embryonic Tissue
 Blood Antibodies  >5 publications with PLK4 and Blood
 Brain Antibodies  >5 publications with PLK4 and Brain
 Skin Antibodies  >4 publications with PLK4 and Skin
 Testis Antibodies  >4 publications with PLK4 and Testis
 Placenta Antibodies  >3 publications with PLK4 and Placenta
 Trachea Antibodies  >3 publications with PLK4 and Trachea
 Bone Antibodies  >3 publications with PLK4 and Bone
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