NP_689414.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
93,386 Da
NCBI Official Full Name
taste receptor type 1 member 3
NCBI Official Synonym Full Names
taste 1 receptor member 3
NCBI Official Synonym Symbols
NCBI Protein Information
taste receptor type 1 member 3
UniProt Protein Name
Taste receptor type 1 member 3
UniProt Synonym Protein Names
Sweet taste receptor T1R3
UniProt Synonym Gene Names
UniProt Entry Name
TS1R3_HUMAN
NCBI Summary for TAS1R3
The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. [provided by RefSeq, Nov 2015]
UniProt Comments for TAS1R3
TAS1R3: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.
Protein type: GPCR, family 3; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: integral to membrane; plasma membrane
Molecular Function: protein heterodimerization activity; sweet taste receptor activity; taste receptor activity
Biological Process: detection of chemical stimulus involved in sensory perception of sweet taste; G-protein coupled receptor protein signaling pathway; sensory perception of sweet taste; sensory perception of umami taste
Research Articles on TAS1R3
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Pathways associated with TAS1R3 blocking peptide
Diseases associated with TAS1R3 blocking peptide
Organs/Tissues associated with TAS1R3 blocking peptide
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