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TGFBR3 peptide

Scan QR to view Datasheet Catalog #    MBS426058 TGFBR3 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TGFBR3, Peptide

 Also Known As   

TGFBR3 Immunizing Peptide

 Product Synonym Names    TGFBR3; transforming growth factor, beta receptor III; BGCAN; betaglycan; betaglycan proteoglycan
 Product Gene Name   

TGFBR3 peptide

[Similar Products]
 Antibody/Peptide Pairs    TGFBR3 peptide (MBS426058) is used for blocking the activity of TGFBR3 antibody (MBS421888)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-TKSIRDDI PSTQGN
 OMIM    600742
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of TGFBR3 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for TGFBR3. It may not necessarily be applicable to this product.
 NCBI GI #    56682966
 NCBI GeneID    7049
 NCBI Accession #    NP_003234.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003243.4 [Other Products]
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 UniProt Secondary Accession #    Q5T2T4; Q5U731; Q9UGI2; A0AUW8; A8K5N0; B9EG88 [Other Products]
 UniProt Related Accession #    Q03167 [Other Products]
 Molecular Weight    93,428 Da
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 NCBI Official Full Name    transforming growth factor beta receptor type 3 isoform a
 NCBI Official Synonym Full Names    transforming growth factor beta receptor 3
 NCBI Official Symbol    TGFBR3 [Similar Products]
 NCBI Official Synonym Symbols   
BGCAN; betaglycan
[Similar Products]
 NCBI Protein Information    transforming growth factor beta receptor type 3
 UniProt Protein Name    Transforming growth factor beta receptor type 3
 UniProt Synonym Protein Names   
Betaglycan; Transforming growth factor beta receptor III; TGF-beta receptor type III
 Protein Family    Transforming growth factor
 UniProt Gene Name    TGFBR3 [Similar Products]
 UniProt Synonym Gene Names    TGF-beta receptor type 3; TGFR-3; TGF-beta receptor type III [Similar Products]
 UniProt Entry Name    TGBR3_HUMAN
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 NCBI Summary for TGFBR3    This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]
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 UniProt Comments for TGFBR3    TGFBR3: Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. Interacts with TCTEX1D4. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p33-p32

Cellular Component: cell surface; cytoplasm; external side of plasma membrane; extracellular space; integral to plasma membrane; proteinaceous extracellular matrix; receptor complex

Molecular Function: activin binding; coreceptor activity; fibroblast growth factor binding; glycosaminoglycan binding; heparin binding; PDZ domain binding; protein binding; punt binding; SMAD binding; transforming growth factor beta binding; transforming growth factor beta receptor activity; transforming growth factor beta receptor binding

Biological Process: BMP signaling pathway; cardiac muscle cell proliferation; cell growth; cell migration; epithelial to mesenchymal transition; heart morphogenesis; immune response; liver development; negative regulation of cell motility; negative regulation of epithelial cell proliferation; negative regulation of transforming growth factor beta receptor signaling pathway; organ regeneration; palate development; positive regulation of transforming growth factor beta receptor signaling pathway; regulation of protein binding; response to follicle-stimulating hormone stimulus; response to hypoxia; transforming growth factor beta receptor complex assembly; transforming growth factor beta receptor signaling pathway; ventricular cardiac muscle morphogenesis
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 Research Articles on TGFBR3    1. rs1192415 of TGFBR3 is associated with primary open angle glaucoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with TGFBR3 peptideDiseases associated with TGFBR3 peptide
 Products by Pathway  Pathway Diagram
 TGF Beta Signaling Pathway antibodies  TGF Beta Signaling Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >27 publications with TGFBR3 and Skin Diseases
 Disease Models, Animal Antibodies  >26 publications with TGFBR3 and Disease Models, Animal
 Breast Neoplasms Antibodies  >26 publications with TGFBR3 and Breast Neoplasms
 Inflammation Antibodies  >25 publications with TGFBR3 and Inflammation
 Fibrosis Antibodies  >25 publications with TGFBR3 and Fibrosis
 Lung Diseases Antibodies  >23 publications with TGFBR3 and Lung Diseases
 Lung Neoplasms Antibodies  >15 publications with TGFBR3 and Lung Neoplasms
 Neoplasm Metastasis Antibodies  >13 publications with TGFBR3 and Neoplasm Metastasis
 Ovarian Neoplasms Antibodies  >13 publications with TGFBR3 and Ovarian Neoplasms
 Nervous System Diseases Antibodies  >13 publications with TGFBR3 and Nervous System Diseases
Organs/Tissues associated with TGFBR3 peptide
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >76 publications with TGFBR3 and Blood
 Bone Antibodies  >69 publications with TGFBR3 and Bone
 Vascular Antibodies  >51 publications with TGFBR3 and Vascular
 Muscle Antibodies  >44 publications with TGFBR3 and Muscle
 Lung Antibodies  >41 publications with TGFBR3 and Lung
 Ovary Antibodies  >36 publications with TGFBR3 and Ovary
 Brain Antibodies  >32 publications with TGFBR3 and Brain
 Connective Tissue Antibodies  >28 publications with TGFBR3 and Connective Tissue
 Heart Antibodies  >27 publications with TGFBR3 and Heart
 Pituitary Gland Antibodies  >25 publications with TGFBR3 and Pituitary Gland
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