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TRH peptide :: Thyrotropin-Releasing Hormone, Prepro-(TRH) Peptide

Scan QR to view Datasheet Catalog #    MBS659600 TRH peptide
Unit / Price
5 mg  /  $390 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Thyrotropin-Releasing Hormone, Prepro-(TRH), Peptide

 Also Known As   

Thyrotropin-Releasing Hormone, Prepro-(TRH) (160-169) (TRH-Potentiating Peptide)

 Product Synonym Names    Thyrotropin-Releasing Hormone, Prepro-(TRH) (160-169) (TRH-Potentiating Peptide)
 Product Gene Name   

TRH peptide

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 3; NC_000003.11 (129693236..129696781). Location: 3q13.3-q21
 OMIM    613879
 3D Structure    ModBase 3D Structure for P20396
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 Host    Synthetic peptide
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 Purity/Purification    Highly Purified
~95%. Purified by HPLC.
 Form/Format    Supplied as a lyophilized powder.
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 Sequence (linear)    Ser-Phe-Pro-Trp-Met-Glu-Ser-Asp-Val-Thr
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 Preparation and Storage    Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of TRH peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for TRH peptide    Molecular Biology; MB-Peptides
NCBI/Uniprot data below describe general gene information for TRH. It may not necessarily be applicable to this product.
 NCBI GI #    6005920
 NCBI GeneID    7200
 NCBI Accession #    NP_009048.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_007117.4 [Other Products]
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 UniProt Primary Accession #    P20396 [Other Products]
 UniProt Secondary Accession #    Q2TB83; B2R8R1 [Other Products]
 UniProt Related Accession #    P20396 [Other Products]
 Molecular Weight    27,404 Da [Similar Products]
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 NCBI Official Full Name    thyrotropin releasing hormone preproprotein
 NCBI Official Synonym Full Names    thyrotropin-releasing hormone
 NCBI Official Symbol    TRH [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    thyrotropin releasing hormone; protirelin; prothyroliberin; TSH-releasing factor; thyrotropin-releasing factor; pro-thyrotropin-releasing hormone
 UniProt Protein Name    Pro-thyrotropin-releasing hormone
 UniProt Synonym Protein Names   
ProthyroliberinCleaved into the following chain:Thyrotropin-releasing hormone; TRH; Alternative name(s):; Protirelin; TSH-releasing factor; Thyroliberin; Thyrotropin-releasing factor
 Protein Family    Thyrotropin-releasing hormone
 UniProt Gene Name    TRH [Similar Products]
 UniProt Synonym Gene Names    Pro-TRH; TRH; TRF [Similar Products]
 UniProt Entry Name    TRH_HUMAN
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 NCBI Summary for TRH    This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013]
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 UniProt Comments for TRH    Function: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. May promote hair shaft elongation, prolonge the hair cycle growth phase (anagen) and antagonized its termination by TGFB2. May also increase proliferation and inhibited apoptosis of hair matrix keratinocytes. Ref.5

Subcellular location: Secreted.

Tissue specificity: Hypothalamus. Expressed in the hair follicle epithelium (at protein level). Ref.5

Sequence similarities: Belongs to the TRH family.
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 Research Articles on TRH    1. Cpe mutations in mouse may affect processing of prothyrotropin releasing hormone into thyrotropin releasing hormone.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TRH peptidePathways associated with TRH peptide
 Reference Product  PubMed Publications
 PRL peptide  >1751 publications with TRH and PRL
 GHRH peptide  >249 publications with TRH and GHRH
 CCK peptide  >62 publications with TRH and CCK
 TRHR peptide  >47 publications with TRH and TRHR
 NTS peptide  >14 publications with TRH and NTS
 GRP peptide  >8 publications with TRH and GRP
 GCG peptide  >2 publications with TRH and GCG
 GNRH1 peptide  >1 publications with TRH and GNRH1
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
Diseases associated with TRH peptideOrgans/Tissues associated with TRH peptide
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1989 publications with TRH and Nervous System Diseases
 Brain Diseases Antibodies  >1676 publications with TRH and Brain Diseases
 Disease Models, Animal Antibodies  >130 publications with TRH and Disease Models, Animal
 Bipolar Disorder Antibodies  >102 publications with TRH and Bipolar Disorder
 Seizures Antibodies  >94 publications with TRH and Seizures
 Hypothermia Antibodies  >91 publications with TRH and Hypothermia
 Hypertension Antibodies  >89 publications with TRH and Hypertension
 Pain Antibodies  >83 publications with TRH and Pain
 Movement Disorders Antibodies  >60 publications with TRH and Movement Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4632 publications with TRH and Brain
 Ovary Antibodies  >123 publications with TRH and Ovary
 Lung Antibodies  >111 publications with TRH and Lung
 Eye Antibodies  >109 publications with TRH and Eye
 Pineal Gland Antibodies  >48 publications with TRH and Pineal Gland
 Bone Marrow Antibodies  >12 publications with TRH and Bone Marrow
 Cervix Antibodies  >3 publications with TRH and Cervix
 Uncharacterized Tissue Antibodies  >1 publications with TRH and Uncharacterized Tissue
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