Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Peptide rightarrow TYR  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • CST complex subunit STN1 (OBFC1) Recombinant Protein
 • actin alpha-skeletal (ACTA1) Antibody
 • Human Immunoglobulin Antibody
 • Visinin Like Protein 1 (VSNL1) ELISA Kit
 • L(+)-Arabinose Carbohydrate/Glycoprotein
 • Leukotriene E4 (LT-E4) ELISA Kit
 • Alcohol dehydrogenase 1B (ADH1B) Recombinant Protein
 • kelch-like 18 (klhl18) Antibody
 • triosephosphate isomerase 1 Antibody
 • Prolactin (PRL) ELISA Kit
 • Bromodomain-containing protein 2 (BRD2), partial Recombinant Protein
 • Interleukin 1beta (IL-1B) ELISA Kit
 • CD26 Antibody
 • SLCO1B3 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

TYR peptide :: Tyrosinase Peptide

Scan QR to view Datasheet Catalog #    MBS8247115
Structure
Unit / Price
1 mg  /  $170 +1 FREE 8GB USB
5 mg  /  $295 +1 FREE 8GB USB
10 mg  /  $425 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tyrosinase, Peptide

 Also Known As   

Tyrosinase (192-200) (Human, Mouse)

 Product Gene Name   

TYR peptide

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    103470
Section Bar
 Host    Synthetic
Section Bar
 Purity/Purification    > 95%
 Form/Format    Lyophilized Powder
Section Bar
 CAS Number    170294-35-6
 Molecular Formula    C54H77N13O17
 Chemical Structure    Ser-Glu-Ile-Trp-Arg-Asp-Ile-Asp-Phe
Section Bar
 Preparation and Storage    Shipped at 4 degree C. Store at -20 degree C for one year.
 Other Notes    Small volumes of TYR peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for TYR peptide

   Peptide to Tyrosinase (192-200) (Human, Mouse)
Section Bar
 Structure of TYR peptide    TYR peptide Structure image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for TYR. It may not necessarily be applicable to this product.
 NCBI GI #    4507753
 NCBI GeneID    7299
 NCBI Accession #    NP_000363.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000372.4 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q15675; Q15676; Q15680; Q8TAK4; Q9BYY0; Q9BZX1 [Other Products]
 UniProt Related Accession #    P14679 [Other Products]
 Molecular Weight    1180.29 [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    tyrosinase
 NCBI Official Synonym Full Names    tyrosinase
 NCBI Official Symbol    TYR [Similar Products]
 NCBI Official Synonym Symbols   
ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3
[Similar Products]
 NCBI Protein Information    tyrosinase
 UniProt Protein Name    Tyrosinase
 UniProt Synonym Protein Names   
LB24-AB; Monophenol monooxygenase; SK29-AB; Tumor rejection antigen AB
 Protein Family    Tyrosinase
 UniProt Gene Name    TYR [Similar Products]
 UniProt Entry Name    TYRO_HUMAN
Section Bar
 NCBI Summary for TYR    The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]
Section Bar
 UniProt Comments for TYR    TYR: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone. Increased expression after UVB irradiation. Belongs to the tyrosinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; Membrane protein, integral; Amino Acid Metabolism - tyrosine; Cofactor and Vitamin Metabolism - riboflavin; EC 1.14.18.1

Chromosomal Location of Human Ortholog: 11q14.3

Cellular Component: cytoplasm; Golgi-associated vesicle; lysosome; melanosome; melanosome membrane; perinuclear region of cytoplasm

Molecular Function: copper ion binding; monooxygenase activity; monophenol monooxygenase activity; protein binding; protein heterodimerization activity; protein homodimerization activity

Biological Process: eye pigment biosynthetic process; melanin biosynthetic process; melanin biosynthetic process from tyrosine; visual perception

Disease: Albinism, Ocular, With Sensorineural Deafness; Albinism, Oculocutaneous, Type Ia; Albinism, Oculocutaneous, Type Ib; Skin/hair/eye Pigmentation, Variation In, 3
Table BarTOPTable Bar
 Research Articles on TYR    1. Four missense substitutions (p.Arg239Trp, p.Ser192Tyr, p.Ser44Arg and p.Arg77Gln) were identified in tyrosinase in the families with oculocutaneous albinism linkage, and another missense substitution (p.Gln272Lys) was identified in the family with OCA4 linkage
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products related to Tyrosinase (192-200) (Human, Mouse)
 Catalog #  Product Name  Catalog #  Product Name
 MBS438299  Tyrosinase-Related Protein-1 (TRP-1)  MBS079157  Camel Tyrosinase ELISA Kit
 MBS452185  Human Tyrosinase (TYR) ELISA Kit  MBS1098295  Recombinant Tyrosinase (melC2)
 MBS438734  Tyrosinase (Melanoma Marker) Mouse Monoclonal Antibody  MBS736149  Goat Tyrosinase ELISA Kit
 MBS734579  Sheep Tyrosinase ELISA Kit  MBS853725  Tyrosinase Antibody
 MBS736196  Monkey Tyrosinase ELISA Kit  MBS1385540  Recombinant Putative tyrosinase-like protein tyr-3 (tyr-3), partial
Pathways associated with TYR peptideDiseases associated with TYR peptide
 Products by Pathway  Pathway Diagram
 (S)-reticuline Biosynthesis Pathway antibodies  (S)-reticuline Biosynthesis Pathway Diagram
 (S)-reticuline Biosynthesis II Pathway antibodies  (S)-reticuline Biosynthesis II Pathway Diagram
 Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway antibodies  Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway Diagram
 Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway antibodies  Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway Diagram
 Dopamine Metabolism Pathway antibodies  Dopamine Metabolism Pathway Diagram
 L-dopachrome Biosynthesis Pathway antibodies  L-dopachrome Biosynthesis Pathway Diagram
 L-dopachrome Biosynthesis Pathway antibodies  L-dopachrome Biosynthesis Pathway Diagram
 Melanin Biosynthesis Pathway antibodies  Melanin Biosynthesis Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >855 publications with TYR and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >447 publications with TYR and Cardiovascular Diseases
 Pain Antibodies  >430 publications with TYR and Pain
 Inflammation Antibodies  >426 publications with TYR and Inflammation
 Melanoma Antibodies  >371 publications with TYR and Melanoma
 Neoplasms, Experimental Antibodies  >286 publications with TYR and Neoplasms, Experimental
 Liver Diseases Antibodies  >232 publications with TYR and Liver Diseases
 Necrosis Antibodies  >228 publications with TYR and Necrosis
 Hypertension Antibodies  >216 publications with TYR and Hypertension
 Kidney Diseases Antibodies  >185 publications with TYR and Kidney Diseases
Organs/Tissues associated with TYR peptide
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >576 publications with TYR and Skin
 Eye Antibodies  >298 publications with TYR and Eye
 Thyroid Antibodies  >189 publications with TYR and Thyroid
 Connective Tissue Antibodies  >141 publications with TYR and Connective Tissue
 Mammary Gland Antibodies  >43 publications with TYR and Mammary Gland
 Ear Antibodies  >31 publications with TYR and Ear
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions