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UCP2 peptide :: Uncoupling protein 2 / UCP2 Peptide

Scan QR to view Datasheet Catalog #    MBS425926 UCP2 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Uncoupling protein 2 / UCP2, Peptide

 Also Known As   

Uncoupling protein 2 / UCP2 Immunizing Peptide

 Product Synonym Names    UCP2; uncoupling protein 2 (mitochondrial, proton carrier); SLC25A8; UCPH; uncoupling protein 2; uncoupling protein-2; Uncoupling protein 2; Uncoupling protein 2 / UCP2
 Product Gene Name   

UCP2 peptide

[Similar Products]
 Antibody/Peptide Pairs    Uncoupling protein 2 / UCP2 peptide (MBS425926) is used for blocking the activity of Uncoupling protein 2/UCP2 antibody (MBS420657)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-DSVKQFYT KGSEH
 OMIM    601693
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 Species Reactivity    Human, Mouse, Rat, Dog
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of UCP2 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for UCP2. It may not necessarily be applicable to this product.
 NCBI GI #    13259541
 NCBI GeneID    7351
 NCBI Accession #    NP_003346.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003355.2 [Other Products]
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 UniProt Secondary Accession #    Q4PJH8; Q53HM3 [Other Products]
 UniProt Related Accession #    P55851 [Other Products]
 Molecular Weight    33,229 Da
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 NCBI Official Full Name    mitochondrial uncoupling protein 2
 NCBI Official Synonym Full Names    uncoupling protein 2
 NCBI Official Symbol    UCP2 [Similar Products]
 NCBI Official Synonym Symbols   
UCPH; BMIQ4; SLC25A8
[Similar Products]
 NCBI Protein Information    mitochondrial uncoupling protein 2
 UniProt Protein Name    Mitochondrial uncoupling protein 2
 UniProt Synonym Protein Names   
Solute carrier family 25 member 8; UCPH
 UniProt Gene Name    UCP2 [Similar Products]
 UniProt Synonym Gene Names    SLC25A8; UCP 2 [Similar Products]
 UniProt Entry Name    UCP2_HUMAN
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 NCBI Summary for UCP2    Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [provided by RefSeq, Jul 2008]
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 UniProt Comments for UCP2    UCP2: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. Belongs to the mitochondrial carrier family.

Protein type: Transporter; Mitochondrial; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: integral to membrane; mitochondrial inner membrane

Molecular Function: protein binding; structural constituent of ribosome

Biological Process: aging; cellular response to amino acid starvation; cellular response to insulin stimulus; female pregnancy; mitochondrial transport; negative regulation of apoptosis; proton transport; regulation of mitochondrial membrane potential; response to hypoxia; response to superoxide; translation; transport

Disease: Body Mass Index Quantitative Trait Locus 4
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 Research Articles on UCP2    1. Data reported here suggest that the UCP2 -866A/55Val/Ins haplotype is associated with an increased risk for DKD and with a lower eGFR in T2DM patients
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with UCP2 peptidePathways associated with UCP2 peptide
 Reference Product  PubMed Publications
 UCP3 peptide  >491 publications with UCP2 and UCP3
 UCP1 peptide  >350 publications with UCP2 and UCP1
 INS peptide  >66 publications with UCP2 and INS
 SIRT1 peptide  >32 publications with UCP2 and SIRT1
 PPARG peptide  >16 publications with UCP2 and PPARG
 PPARA peptide  >12 publications with UCP2 and PPARA
 NRF1 peptide  >10 publications with UCP2 and NRF1
 LEP peptide  >9 publications with UCP2 and LEP
 GHRL peptide  >2 publications with UCP2 and GHRL
 FOXA2 peptide  >1 publications with UCP2 and FOXA2
 Products by Pathway  Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Energy Metabolism Pathway antibodies  Energy Metabolism Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Mitochondrial Uncoupling Proteins Pathway antibodies  Mitochondrial Uncoupling Proteins Pathway Diagram
 Respiratory Electron Transport, ATP Synthesis By Chemiosmotic Coupling, And Heat Production By Uncoupling Proteins. Pathway antibodies  Respiratory Electron Transport, ATP Synthesis By Chemiosmotic Coupling, And Heat Production By Uncoupling Proteins. Pathway Diagram
 The Citric Acid (TCA) Cycle And Respiratory Electron Transport Pathway antibodies  The Citric Acid (TCA) Cycle And Respiratory Electron Transport Pathway Diagram
 The Fatty Acid Cycling Model Pathway antibodies  The Fatty Acid Cycling Model Pathway Diagram
 The Proton Buffering Model Pathway antibodies  The Proton Buffering Model Pathway Diagram
Diseases associated with UCP2 peptideOrgans/Tissues associated with UCP2 peptide
 Disease Name  Pubmed Publications
 Obesity Antibodies  >372 publications with UCP2 and Obesity
 Fatty Liver Antibodies  >118 publications with UCP2 and Fatty Liver
 Cardiovascular Diseases Antibodies  >116 publications with UCP2 and Cardiovascular Diseases
 Insulin Resistance Antibodies  >108 publications with UCP2 and Insulin Resistance
 Diabetes Mellitus, Type 2 Antibodies  >107 publications with UCP2 and Diabetes Mellitus, Type 2
 Disease Models, Animal Antibodies  >102 publications with UCP2 and Disease Models, Animal
 Inflammation Antibodies  >90 publications with UCP2 and Inflammation
 Liver Diseases Antibodies  >70 publications with UCP2 and Liver Diseases
 Nervous System Diseases Antibodies  >67 publications with UCP2 and Nervous System Diseases
 Necrosis Antibodies  >62 publications with UCP2 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Adipose Tissue Antibodies  >369 publications with UCP2 and Adipose Tissue
 Muscle Antibodies  >353 publications with UCP2 and Muscle
 Blood Antibodies  >292 publications with UCP2 and Blood
 Connective Tissue Antibodies  >249 publications with UCP2 and Connective Tissue
 Liver Antibodies  >232 publications with UCP2 and Liver
 Brain Antibodies  >164 publications with UCP2 and Brain
 Heart Antibodies  >127 publications with UCP2 and Heart
 Pancreas Antibodies  >120 publications with UCP2 and Pancreas
 Vascular Antibodies  >62 publications with UCP2 and Vascular
 Kidney Antibodies  >54 publications with UCP2 and Kidney
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