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UCN3 peptide :: Urocortin 3 Peptide

Scan QR to view Datasheet Catalog #    MBS426455 UCN3 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Urocortin 3 (UCN3), Peptide

 Also Known As   

Urocortin 3 Immunizing Peptide

 Product Synonym Names    UCN3; urocortin 3 (stresscopin); MGC119002; SCP; SPC; UCNIII; stresscopin; urocortin 3; urocortin III; Urocortin 3; Urocortin 3
 Product Gene Name   

UCN3 peptide

[Similar Products]
 Antibody/Peptide Pairs    Urocortin 3 peptide (MBS426455) is used for blocking the activity of Urocortin 3 antibody (MBS421585)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-KPRQDTAK SPHRTK
 OMIM    605901
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of UCN3 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for UCN3. It may not necessarily be applicable to this product.
 NCBI GI #    45238845
 NCBI GeneID    114131
 NCBI Accession #    NP_444277.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_053049.3 [Other Products]
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 UniProt Secondary Accession #    Q496H2; Q5SR91 [Other Products]
 UniProt Related Accession #    Q969E3 [Other Products]
 Molecular Weight    17,961 Da
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 NCBI Official Full Name    urocortin-3 preproprotein
 NCBI Official Synonym Full Names    urocortin 3
 NCBI Official Symbol    UCN3 [Similar Products]
 NCBI Official Synonym Symbols   
SCP; SPC; UCNIII
[Similar Products]
 NCBI Protein Information    urocortin-3
 UniProt Protein Name    Urocortin-3
 UniProt Synonym Protein Names   
Stresscopin; Urocortin III; Ucn III
 Protein Family    Urocortin
 UniProt Gene Name    UCN3 [Similar Products]
 UniProt Synonym Gene Names    SPC; Ucn III [Similar Products]
 UniProt Entry Name    UCN3_HUMAN
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 NCBI Summary for UCN3    This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite. [provided by RefSeq, May 2016]
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 UniProt Comments for UCN3    UCN3: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10p15.1

Cellular Component: extracellular space

Molecular Function: corticotropin-releasing hormone receptor 2 binding; G-protein-coupled receptor binding; hormone activity

Biological Process: cellular response to nutrient levels; digestion; G-protein signaling, adenylate cyclase activating pathway; response to stress
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 Research Articles on UCN3    1. results show that activation of CRH receptors by CRH ligands stimulates VEGF-A expression in intestinal epithelial cells through the cAMP/CREB pathway
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with UCN3 peptideOrgans/Tissues associated with UCN3 peptide
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >13 publications with UCN3 and Inflammation
 Vascular Diseases Antibodies  >6 publications with UCN3 and Vascular Diseases
 Immune System Diseases Antibodies  >5 publications with UCN3 and Immune System Diseases
 Diabetes Mellitus Antibodies  >5 publications with UCN3 and Diabetes Mellitus
 Insulin Resistance Antibodies  >4 publications with UCN3 and Insulin Resistance
 Edema Antibodies  >4 publications with UCN3 and Edema
 Hypertrophy Antibodies  >3 publications with UCN3 and Hypertrophy
 Depressive Disorder Antibodies  >3 publications with UCN3 and Depressive Disorder
 Carcinoma Antibodies  >2 publications with UCN3 and Carcinoma
 Neurologic Manifestations Antibodies  >2 publications with UCN3 and Neurologic Manifestations
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >5 publications with UCN3 and Pancreas
 Mixed Antibodies  >1 publications with UCN3 and Mixed
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