NP_060436.4
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,659 Da
NCBI Official Full Name
vacuolar protein sorting-associated protein 37C
NCBI Official Synonym Full Names
VPS37C, ESCRT-I subunit
NCBI Protein Information
vacuolar protein sorting-associated protein 37C
UniProt Protein Name
Vacuolar protein sorting-associated protein 37C
UniProt Synonym Protein Names
ESCRT-I complex subunit VPS37C
UniProt Synonym Gene Names
UniProt Entry Name
VP37C_HUMAN
NCBI Summary for VPS37C
VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008]
UniProt Comments for VPS37C
VPS37C: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. Belongs to the VPS37 family.
Chromosomal Location of Human Ortholog: 11q12.2
Cellular Component: endosome membrane; late endosome membrane
Molecular Function: calcium-dependent protein binding; protein binding
Biological Process: autophagy; endosome transport; protein transport; viral infectious cycle
Research Articles on VPS37C
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with VPS37C blocking peptide
|