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ARR3 peptide :: X-arrestin / arrestin 3 Peptide

Scan QR to view Datasheet Catalog #    MBS425931 ARR3 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

X-arrestin / arrestin 3 (ARR3), Peptide

 Also Known As   

X-arrestin / arrestin 3 Immunizing Peptide

 Product Synonym Names    ARR3; arrestin 3, retinal (X-arrestin); RP13-26D14. 6; ARRX; Arrestin C; X-arrestin; arrestin 3; X-arrestin / arrestin 3
 Product Gene Name   

ARR3 peptide

[Similar Products]
 Antibody/Peptide Pairs    X-arrestin / arrestin 3 peptide (MBS425931) is used for blocking the activity of X-arrestin/arrestin 3 antibody (MBS422109)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-RKGEEESQ KAVE
 OMIM    301770
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of ARR3 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ARR3. It may not necessarily be applicable to this product.
 NCBI GI #    156071467
 NCBI GeneID    407
 NCBI Accession #    NP_004303.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_004312.2 [Other Products]
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 UniProt Secondary Accession #    Q5JT23; Q5JT24; Q6IBF5; Q96EN2; B5B0B9 [Other Products]
 UniProt Related Accession #    P36575 [Other Products]
 Molecular Weight    39,667 Da
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 NCBI Official Full Name    arrestin-C
 NCBI Official Synonym Full Names    arrestin 3 retinal (X-arrestin)
 NCBI Official Symbol    ARR3 [Similar Products]
 NCBI Official Synonym Symbols   
ARRX; cArr
[Similar Products]
 NCBI Protein Information    arrestin-C
 UniProt Protein Name    Arrestin-C
 UniProt Synonym Protein Names   
Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin
 Protein Family    Arrestin
 UniProt Gene Name    ARR3 [Similar Products]
 UniProt Synonym Gene Names    ARRX; CAR; C-arrestin; cArr [Similar Products]
 UniProt Entry Name    ARRC_HUMAN
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 NCBI Summary for ARR3    The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016]
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 UniProt Comments for ARR3    ARR3: May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins. Belongs to the arrestin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: Xcen-q21

Cellular Component: cytoplasm; photoreceptor inner segment; photoreceptor outer segment; synapse

Molecular Function: opsin binding; phosphoprotein binding; protein binding; protein domain specific binding

Biological Process: endocytosis; regulation of protein amino acid phosphorylation; signal transduction; visual perception
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 Research Articles on ARR3    1. In the cell membrane, arrestin-3 dissociates quickly and almost completely from the Beta2-adrenoceptor.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ARR3 peptideDiseases associated with ARR3 peptide
 Products by Pathway  Pathway Diagram
 CXCR4-mediated Signaling Events Pathway antibodies  CXCR4-mediated Signaling Events Pathway Diagram
 Thromboxane A2 Receptor Signaling Pathway antibodies  Thromboxane A2 Receptor Signaling Pathway Diagram
 Visual Signal Transduction: Cones Pathway antibodies  Visual Signal Transduction: Cones Pathway Diagram
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >2 publications with ARR3 and Disease Models, Animal
 Diabetes Mellitus, Type 2 Antibodies  >1 publications with ARR3 and Diabetes Mellitus, Type 2
 Inflammation Antibodies  >1 publications with ARR3 and Inflammation
Organs/Tissues associated with ARR3 peptide
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >7 publications with ARR3 and Eye
 Muscle Antibodies  >2 publications with ARR3 and Muscle
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