NP_149123.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
68,448 Da
NCBI Official Full Name
zinc finger protein ZIC 5
NCBI Official Synonym Full Names
Zic family member 5
NCBI Protein Information
zinc finger protein ZIC 5
UniProt Protein Name
Zinc finger protein ZIC 5
UniProt Synonym Protein Names
Zinc finger protein of the cerebellum 5
UniProt Entry Name
ZIC5_HUMAN
NCBI Summary for ZIC5
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 2, a related family member on chromosome 13. [provided by RefSeq, Jul 2008]
UniProt Comments for ZIC5
ZIC5: Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA. Belongs to the GLI C2H2-type zinc-finger protein family.
Protein type: C2H2-type zinc finger protein; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 13q32.3
Cellular Component: nucleus
Molecular Function: DNA binding; metal ion binding
Biological Process: cell differentiation; nervous system development
Research Articles on ZIC5
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Pathways associated with ZIC5 blocking peptide
Diseases associated with ZIC5 blocking peptide
Organs/Tissues associated with ZIC5 blocking peptide
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