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ZYX peptide

Scan QR to view Datasheet Catalog #    MBS426068 ZYX peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ZYX, Peptide

 Also Known As   

ZYX Immunizing Peptide

 Product Synonym Names    ZYX; zyxin; ESP-2; HED-2
 Product Gene Name   

ZYX peptide

[Similar Products]
 Antibody/Peptide Pairs    ZYX peptide (MBS426068) is used for blocking the activity of ZYX antibody (MBS422246)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-QQREKPRV QEKQH
 OMIM    602002
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 Species Reactivity    Human, Dog
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of ZYX peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ZYX. It may not necessarily be applicable to this product.
 NCBI GI #    4508047
 NCBI GeneID    7791
 NCBI Accession #    NP_003452.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003461.4 [Other Products]
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 UniProt Secondary Accession #    Q6I9S4; A4D2G6; B4DQX7 [Other Products]
 UniProt Related Accession #    Q15942 [Other Products]
 Molecular Weight    45,075 Da
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 NCBI Official Full Name    zyxin
 NCBI Official Synonym Full Names    zyxin
 NCBI Official Symbol    ZYX [Similar Products]
 NCBI Official Synonym Symbols   
ESP-2; HED-2
[Similar Products]
 NCBI Protein Information    zyxin
 UniProt Protein Name    Zyxin
 UniProt Synonym Protein Names   
Zyxin-2
 Protein Family    Zyxin
 UniProt Gene Name    ZYX [Similar Products]
 UniProt Entry Name    ZYX_HUMAN
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 NCBI Summary for ZYX    Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ZYX    Zyxin: Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression. Interacts with HPV type 6 protein E6. Does not interact significantly with E6 proteins from HPV types 11, 16, or 18. Interacts, via the Pro-rich regions, with the EVH1 domains of ENAH, EVL and VASP. Interacts with the first LIM domain of TES. Interacts with NEBL (isoform 2). Belongs to the zyxin/ajuba family.

Protein type: Cell adhesion; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7q32

Cellular Component: cell-cell adherens junction; cytoplasm; focal adhesion; integral to plasma membrane; nucleus; plasma membrane; stress fiber

Molecular Function: protein binding; zinc ion binding

Biological Process: cell adhesion; cell-cell signaling; cell-matrix adhesion; integrin-mediated signaling pathway; regulation of inflammatory response; signal transduction; stress fiber formation; transforming growth factor beta receptor signaling pathway; viral reproduction
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 Research Articles on ZYX    1. ZYX gene may be aging-related gene and involved in Osteoporosis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ZYX peptidePathways associated with ZYX peptide
 Reference Product  PubMed Publications
 VASP peptide  >36 publications with ZYX and VASP
 PTK2 peptide  >4 publications with ZYX and PTK2
 LASP1 peptide  >4 publications with ZYX and LASP1
 VCL peptide  >3 publications with ZYX and VCL
 BCAR1 peptide  >3 publications with ZYX and BCAR1
 ACTN1 peptide  >2 publications with ZYX and ACTN1
 LATS1 peptide  >1 publications with ZYX and LATS1
 VAV1 peptide  >1 publications with ZYX and VAV1
 Products by Pathway  Pathway Diagram
 E-cadherin Signaling In Keratinocytes Pathway antibodies  E-cadherin Signaling In Keratinocytes Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Integrin-mediated Cell Adhesion Pathway antibodies  Integrin-mediated Cell Adhesion Pathway Diagram
 Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway antibodies  Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway Diagram
Diseases associated with ZYX peptideOrgans/Tissues associated with ZYX peptide
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >7 publications with ZYX and Breast Neoplasms
 Lung Diseases Antibodies  >6 publications with ZYX and Lung Diseases
 Nervous System Diseases Antibodies  >5 publications with ZYX and Nervous System Diseases
 Cell Transformation, Neoplastic Antibodies  >5 publications with ZYX and Cell Transformation, Neoplastic
 Hypertension Antibodies  >4 publications with ZYX and Hypertension
 Lung Neoplasms Antibodies  >4 publications with ZYX and Lung Neoplasms
 Hypertrophy Antibodies  >3 publications with ZYX and Hypertrophy
 Neoplasm Metastasis Antibodies  >3 publications with ZYX and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >3 publications with ZYX and Adenocarcinoma
 Necrosis Antibodies  >3 publications with ZYX and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >21 publications with ZYX and Muscle
 Blood Antibodies  >13 publications with ZYX and Blood
 Lung Antibodies  >12 publications with ZYX and Lung
 Vascular Antibodies  >11 publications with ZYX and Vascular
 Thyroid Antibodies  >9 publications with ZYX and Thyroid
 Embryonic Tissue Antibodies  >9 publications with ZYX and Embryonic Tissue
 Heart Antibodies  >8 publications with ZYX and Heart
 Brain Antibodies  >8 publications with ZYX and Brain
 Bone Antibodies  >7 publications with ZYX and Bone
 Skin Antibodies  >5 publications with ZYX and Skin
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