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MYB peptide :: c-Myb Peptide

Scan QR to view Datasheet Catalog #    MBS427353 MYB peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

c-Myb, Peptide

 Also Known As   

c-Myb Immunizing Peptide

 Product Synonym Names    MYB; v-myb myeloblastosis viral oncogene homolog (avian); Cmyb; c-myb; c-myb_CDS; efg; c-myb protein (140 AA); c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; v-myb myeloblastosis viral oncogene homolog; c-Myb (aa557-569)
 Product Gene Name   

MYB peptide

[Similar Products]
 Product Synonym Gene Name    c-Myb [Similar Products]
 Antibody/Peptide Pairs    c-Myb peptide (MBS427353) is used for blocking the activity of c-Myb antibody (MBS422371)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-HRDQTVKT QKENT
 OMIM    189990
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 Species Reactivity    Human, Mouse, Rat, Dog, Cow, Pig
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of MYB peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for MYB. It may not necessarily be applicable to this product.
 NCBI GI #    194328729
 NCBI GeneID    4602
 NCBI Accession #    NP_001123645.1 [Other Products]
 NCBI Related Accession #    NP_005366.2; NP_001123644.1; NP_001155128.1; NP_001155129.1; NP_001155130.1; NP_001155131.1; NP_001155132.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001130173.1 [Other Products]
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 UniProt Secondary Accession #    P78391; P78392; P78525; P78526; Q14023; Q14024; E9PI07; E9PLZ5; E9PNA4; E9PNL6; E9PRS2 [Other Products]
 UniProt Related Accession #    P10242 [Other Products]
 Molecular Weight    37,507 Da
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 NCBI Official Full Name    transcriptional activator Myb isoform 1
 NCBI Official Synonym Full Names    MYB proto-oncogene, transcription factor
 NCBI Official Symbol    MYB [Similar Products]
 NCBI Official Synonym Symbols   
efg; Cmyb; c-myb; c-myb_CDS
[Similar Products]
 NCBI Protein Information    transcriptional activator Myb
 UniProt Protein Name    Transcriptional activator Myb
 UniProt Synonym Protein Names   
Proto-oncogene c-Myb
 Protein Family    Myb protein
 UniProt Gene Name    MYB [Similar Products]
 UniProt Entry Name    MYB_HUMAN
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 NCBI Summary for MYB    This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
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 UniProt Comments for MYB    Myb: Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; DNA-binding; Oncoprotein

Chromosomal Location of Human Ortholog: 6q22-q23

Cellular Component: nuclear matrix

Molecular Function: protein binding

Biological Process: chromatin remodeling; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of histone H3-K4 methylation; positive regulation of histone H3-K9 methylation; positive regulation of T-helper cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter
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 Research Articles on MYB    1. MYB is aberrantly overexpressed in PC cells and acts as a key determinant of pancreatic tumour growth and metastasis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MYB peptidePathways associated with MYB peptide
 Reference Product  PubMed Publications
 MYC peptide  >783 publications with MYB and MYC
 BCL2 peptide  >26 publications with MYB and BCL2
 CREBBP peptide  >24 publications with MYB and CREBBP
 EP300 peptide  >20 publications with MYB and EP300
 GATA3 peptide  >18 publications with MYB and GATA3
 PAX5 peptide  >7 publications with MYB and PAX5
 NLK peptide  >5 publications with MYB and NLK
 CEBPB peptide  >3 publications with MYB and CEBPB
 MYOD1 peptide  >3 publications with MYB and MYOD1
 Products by Pathway  Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 IL2 Signaling Events Mediated By PI3K Pathway antibodies  IL2 Signaling Events Mediated By PI3K Pathway Diagram
 IL4-mediated Signaling Events Pathway antibodies  IL4-mediated Signaling Events Pathway Diagram
 Neural Crest Differentiation Pathway antibodies  Neural Crest Differentiation Pathway Diagram
 Notch-mediated HES/HEY Network Pathway antibodies  Notch-mediated HES/HEY Network Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
Diseases associated with MYB peptideOrgans/Tissues associated with MYB peptide
 Disease Name  Pubmed Publications
 Neoplasms, Experimental Antibodies  >130 publications with MYB and Neoplasms, Experimental
 Adenocarcinoma Antibodies  >116 publications with MYB and Adenocarcinoma
 Breast Neoplasms Antibodies  >110 publications with MYB and Breast Neoplasms
 Carcinoma, Adenoid Cystic Antibodies  >77 publications with MYB and Carcinoma, Adenoid Cystic
 Anemia Antibodies  >76 publications with MYB and Anemia
 Nervous System Diseases Antibodies  >54 publications with MYB and Nervous System Diseases
 Inflammation Antibodies  >51 publications with MYB and Inflammation
 Cardiovascular Diseases Antibodies  >49 publications with MYB and Cardiovascular Diseases
 Lung Neoplasms Antibodies  >45 publications with MYB and Lung Neoplasms
 Necrosis Antibodies  >37 publications with MYB and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >730 publications with MYB and Blood
 Bone Marrow Antibodies  >200 publications with MYB and Bone Marrow
 Liver Antibodies  >132 publications with MYB and Liver
 Skin Antibodies  >128 publications with MYB and Skin
 Lung Antibodies  >91 publications with MYB and Lung
 Thymus Antibodies  >89 publications with MYB and Thymus
 Kidney Antibodies  >66 publications with MYB and Kidney
 Salivary Gland Antibodies  >59 publications with MYB and Salivary Gland
 Lymph Node Antibodies  >50 publications with MYB and Lymph Node
 Eye Antibodies  >42 publications with MYB and Eye
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