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c-Src peptide

Scan QR to view Datasheet Catalog #    MBS443022 c-Src peptide
Unit / Price
0.1 mg  /  $125 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

c-Src, Peptide

 Also Known As   

c-Src (A16) Blocking Peptide

 Product Gene Name   

c-Src peptide

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    190090
 3D Structure    ModBase 3D Structure for P12931
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 Concentration    0.100 mg/0.5 ml (lot specific)
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 Preparation and Storage    Store this product at 4 degree C, do not freeze. The product is stable for one year from the date of shipment.
 Other Notes    Small volumes of c-Src peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for c-Src peptide    Controls
NCBI/Uniprot data below describe general gene information for c-Src. It may not necessarily be applicable to this product.
 NCBI GI #    1848077
 NCBI GeneID    6714
 NCBI Accession #    CAA26485.1 [Other Products]
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 UniProt Primary Accession #    P12931 [Other Products]
 UniProt Secondary Accession #    Q76P87; Q86VB9; Q9H5A8; E1P5V4 [Other Products]
 UniProt Related Accession #    P12931 [Other Products]
 Molecular Weight    60,589 Da
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 NCBI Official Full Name    c-src, partial
 NCBI Official Synonym Full Names    SRC proto-oncogene, non-receptor tyrosine kinase
 NCBI Official Symbol    SRC [Similar Products]
 NCBI Official Synonym Symbols   
ASV; SRC1; c-SRC; p60-Src
[Similar Products]
 NCBI Protein Information    proto-oncogene tyrosine-protein kinase Src; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; tyrosine kinase pp60c-src; tyrosine-protein kinase SRC-1; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
 UniProt Protein Name    Proto-oncogene tyrosine-protein kinase Src
 UniProt Synonym Protein Names   
Proto-oncogene c-Src; pp60c-src; p60-Src
 UniProt Gene Name    SRC [Similar Products]
 UniProt Synonym Gene Names    SRC1; p60-Src [Similar Products]
 UniProt Entry Name    SRC_HUMAN
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 NCBI Summary for c-Src    This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for c-Src    Src: proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme; phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme. Two alternatively spliced isoforms have been described.

Protein type: Protein kinase, tyrosine (non-receptor); Protein kinase, TK; Kinase, protein; Oncoprotein; EC 2.7.10.2; TK group; Src family

Chromosomal Location of Human Ortholog: 20q12-q13

Cellular Component: neuron projection; mitochondrion; lysosome; postsynaptic density; actin filament; caveola; cytosol; extrinsic to internal side of plasma membrane; perinuclear region of cytoplasm; mitochondrial inner membrane; late endosome; cytoplasm; plasma membrane; nucleus

Molecular Function: protein C-terminus binding; ephrin receptor binding; non-membrane spanning protein tyrosine kinase activity; phosphoprotein binding; insulin receptor binding; protein kinase activity; integrin binding; protein binding; enzyme binding; protein kinase C binding; SH3/SH2 adaptor activity; protein-tyrosine kinase activity; heme binding; estrogen receptor binding; SH2 domain binding; kinase activity; ATP binding; hormone receptor binding; receptor binding

Biological Process: oogenesis; regulation of estrogen receptor signaling pathway; central nervous system development; estrogen receptor signaling pathway; positive regulation of cyclin-dependent protein kinase activity; progesterone receptor signaling pathway; viral reproduction; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; regulation of cell cycle; positive regulation of transcription, DNA-dependent; uterus development; negative regulation of mitochondrial depolarization; negative regulation of protein homooligomerization; positive regulation of MAP kinase activity; cell-cell adhesion; transforming growth factor beta receptor signaling pathway; cell adhesion; response to electrical stimulus; bone resorption; response to drug; platelet activation; fibroblast growth factor receptor signaling pathway; response to virus; activation of protein kinase B; transcytosis; positive regulation of protein amino acid autophosphorylation; positive regulation of integrin activation; cellular response to insulin stimulus; response to mechanical stimulus; T cell costimulation; regulation of vascular permeability; negative regulation of transcription, DNA-dependent; leukocyte migration; negative regulation of apoptosis; axon guidance; peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation; platelet-derived growth factor receptor signaling pathway; negative regulation of caspase activity; positive regulation of smooth muscle cell migration; signal transduction; regulation of cell-cell adhesion; forebrain development; ephrin receptor signaling pathway; response to nutrient levels; epidermal growth factor receptor signaling pathway; integrin-mediated signaling pathway; regulation of bone resorption; negative regulation of focal adhesion formation; signal complex assembly; positive regulation of phosphoinositide 3-kinase activity; response to mineralocorticoid stimulus; cell cycle; regulation of cell proliferation; positive regulation of protein kinase B signaling cascade; cell proliferation; peptidyl-serine phosphorylation; response to hydrogen peroxide; regulation of protein binding; Ras protein signal transduction; stress fiber formation; innate immune response; response to acidity; positive regulation of insulin receptor signaling pathway; blood coagulation; vascular endothelial growth factor receptor signaling pathway; positive regulation of cytokine secretion
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 Research Articles on c-Src    1. Membrane AR activation regulates late expression and/or activity of the tumorigenic gene products c-Src, GSK-3beta. and beta-catenin
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with c-Src peptidePathways associated with c-Src peptide
 Reference Product  PubMed Publications
 EGFR peptide  >1286 publications with c-Src and EGFR
 STAT3 peptide  >840 publications with c-Src and STAT3
 CRK peptide  >647 publications with c-Src and CRK
 PTK2 peptide  >626 publications with c-Src and PTK2
 CBL peptide  >506 publications with c-Src and CBL
 PXN peptide  >175 publications with c-Src and PXN
 BCAR1 peptide  >168 publications with c-Src and BCAR1
 KHDRBS1 peptide  >86 publications with c-Src and KHDRBS1
 PTPN1 peptide  >73 publications with c-Src and PTPN1
 ESR1 peptide  >13 publications with c-Src and ESR1
 Products by Pathway  Pathway Diagram
 ADP Signalling Through P2Y Purinoceptor 1 Pathway antibodies  ADP Signalling Through P2Y Purinoceptor 1 Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 Alpha-synuclein Signaling Pathway antibodies  Alpha-synuclein Signaling Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Angiogenesis Pathway antibodies  Angiogenesis Pathway Diagram
Diseases associated with c-Src peptideOrgans/Tissues associated with c-Src peptide
 Disease Name  Pubmed Publications
 Cell Transformation, Neoplastic Antibodies  >1916 publications with c-Src and Cell Transformation, Neoplastic
 Breast Neoplasms Antibodies  >1111 publications with c-Src and Breast Neoplasms
 Inflammation Antibodies  >878 publications with c-Src and Inflammation
 Disease Models, Animal Antibodies  >846 publications with c-Src and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >795 publications with c-Src and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >787 publications with c-Src and Neoplasms, Experimental
 Nervous System Diseases Antibodies  >719 publications with c-Src and Nervous System Diseases
 Neoplasm Metastasis Antibodies  >676 publications with c-Src and Neoplasm Metastasis
 Necrosis Antibodies  >624 publications with c-Src and Necrosis
 Neoplasm Invasiveness Antibodies  >584 publications with c-Src and Neoplasm Invasiveness
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5266 publications with c-Src and Blood
 Brain Antibodies  >2105 publications with c-Src and Brain
 Muscle Antibodies  >1625 publications with c-Src and Muscle
 Bone Antibodies  >1381 publications with c-Src and Bone
 Kidney Antibodies  >1171 publications with c-Src and Kidney
 Lung Antibodies  >1108 publications with c-Src and Lung
 Nerve Antibodies  >1065 publications with c-Src and Nerve
 Liver Antibodies  >909 publications with c-Src and Liver
 Embryonic Tissue Antibodies  >540 publications with c-Src and Embryonic Tissue
 Prostate Antibodies  >517 publications with c-Src and Prostate
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