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IFI27 positive control

Scan QR to view Datasheet Catalog #    MBS542861 IFI27 positive control
Unit / Price
5 Applications  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IFI27, Positive Control

 Also Known As   

IFI27 Positive Control

 Product Synonym Names    2310061N23Rik; FAM14D; IFI 27; Interferon alpha induced 11.5 kDa protein; Interferon inducible protein 27; interferon-stimulated gene 12; ISG 12; ISG12A; P27 antibody
 Product Gene Name   

IFI27 positive control

[Similar Products]
 Matching Pairs    Antibody: IFI27 (MBS540037)
Positive Control: IFI27 (MBS542861)
 Matching Pairs    Antibody: IFI27 (MBS540215)
Positive Control: IFI27 (MBS542861)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600009
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 Form/Format    Western Blot Positive Control
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 Immunogen    Purified Protein
 Expression    Up-regulated by interferons
 Molecular Function    Lamin binding; RNA polymerase II activating transcription factor binding
 Structure    Belongs to the IFI6/IFI27 family.
 Subcellular Location    Mitochondrion; Multi-pass membrane protein
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 Preparation and Storage    -20 degree C for long term storage
 Other Notes    Small volumes of IFI27 positive control vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for IFI27 positive control

   Western Blot Positive Control Interferon, alpha-inducible protein 27
Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9.
 Applications Tested/Suitable for IFI27 positive control   

Western Blot (WB)

 Application Notes for IFI27 positive control    Western Blot: 1:500
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NCBI/Uniprot data below describe general gene information for IFI27. It may not necessarily be applicable to this product.
 NCBI GI #    55925614
 NCBI GeneID    3429
 NCBI Accession #    NP_005523.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_005532.4 [Other Products]
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 UniProt Secondary Accession #    Q53YA6; Q6IEC1; Q96BK3 [Other Products]
 UniProt Related Accession #    P40305 [Other Products]
 Molecular Weight    11,268 Da
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 NCBI Official Full Name    interferon alpha-inducible protein 27, mitochondrial isoform 2
 NCBI Official Synonym Full Names    interferon alpha inducible protein 27
 NCBI Official Symbol    IFI27 [Similar Products]
 NCBI Official Synonym Symbols   
P27; ISG12; FAM14D; ISG12A
[Similar Products]
 NCBI Protein Information    interferon alpha-inducible protein 27, mitochondrial
 UniProt Protein Name    Interferon alpha-inducible protein 27, mitochondrial
 UniProt Synonym Protein Names   
Interferon alpha-induced 11.5 kDa protein; Interferon-stimulated gene 12a protein; ISG12(a)
 Protein Family    Interferon alpha-inducible protein
 UniProt Gene Name    IFI27 [Similar Products]
 UniProt Synonym Gene Names    p27; ISG12(a) [Similar Products]
 UniProt Entry Name    IFI27_HUMAN
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 UniProt Comments for IFI27    IFI27: Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9. Belongs to the IFI6/IFI27 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 14q32

Cellular Component: integral to membrane; mitochondrial outer membrane; mitochondrion; nuclear inner membrane

Molecular Function: lamin binding

Biological Process: caspase activation; negative regulation of transcription from RNA polymerase II promoter; regulation of protein export from nucleus
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 Research Articles on IFI27    1. IFI27 is involved in proliferation of skin keratinocytes both in vitro and in vivo.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with IFI27 positive controlDiseases associated with IFI27 positive control
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 Interferon Alpha/beta Signaling Pathway antibodies  Interferon Alpha/beta Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >22 publications with IFI27 and Liver Diseases
 Inflammation Antibodies  >12 publications with IFI27 and Inflammation
 Nervous System Diseases Antibodies  >8 publications with IFI27 and Nervous System Diseases
 Carcinoma, Hepatocellular Antibodies  >7 publications with IFI27 and Carcinoma, Hepatocellular
 Breast Neoplasms Antibodies  >4 publications with IFI27 and Breast Neoplasms
 Liver Cirrhosis Antibodies  >4 publications with IFI27 and Liver Cirrhosis
 Adenocarcinoma Antibodies  >4 publications with IFI27 and Adenocarcinoma
 Brain Diseases Antibodies  >4 publications with IFI27 and Brain Diseases
 Liver Neoplasms Antibodies  >4 publications with IFI27 and Liver Neoplasms
 Fibrosis Antibodies  >3 publications with IFI27 and Fibrosis
Organs/Tissues associated with IFI27 positive control
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >32 publications with IFI27 and Blood
 Liver Antibodies  >18 publications with IFI27 and Liver
 Skin Antibodies  >7 publications with IFI27 and Skin
 Vascular Antibodies  >4 publications with IFI27 and Vascular
 Muscle Antibodies  >4 publications with IFI27 and Muscle
 Uterus Antibodies  >3 publications with IFI27 and Uterus
 Brain Antibodies  >3 publications with IFI27 and Brain
 Kidney Antibodies  >3 publications with IFI27 and Kidney
 Bone Antibodies  >2 publications with IFI27 and Bone
 Lymph Node Antibodies  >2 publications with IFI27 and Lymph Node
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