Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Protein rightarrow GPT  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • IGF2-BP2 Antibody
 • IFN-alpha-Ab ELISA Kit
 • Plasminogen (Plg) DIY ELISA Kit
 • Dopamine (DA) ELISA Kit
 • Phosducin-Like Protein 2 (PDCL2) ELISA Kit
 • CLEC5A Antibody
 • Annexin V (ANN V) ELISA Kit
 • Polyvalent Dengue Antigen-I Recombinant Protein
 • Gamma-aminobutyric acid, GABA ELISA Kit
 • REST - NRSF Antibody
 • inhibin beta-B (Inhbb) ELISA Kit
 • Prostate specific antigen (PSA) ELISA Kit
 • involucrin (IVL) ELISA Kit
 • matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 7... ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

GPT protein :: Alanine Aminotransferase Protein

Scan QR to view Datasheet Catalog #    MBS173240 GPT protein
Unit / Price
5000 Units  /  $260 +1 FREE 8GB USB
20000 Units  /  $485 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Alanine Aminotransferase (GPT), Protein

★Popular Item★
 Also Known As   

Glutamate Pyruvate Transaminase (GPT)/Alanine Aminotransferase (ALT), Porcine Heart

 Product Synonym Names    Glutamate Pyruvate Transaminase; Alanine Transaminase; serum glutamic-pyruvic transaminase; SGPT; GPT; ALT; ALAT; Alanine Aminotransferase (ALT, GPT), Porcine Heart - Liquid, Alanine Transaminases (ALT)
 Product Gene Name   

GPT protein

[Similar Products]
 Product Synonym Gene Name    AAT1; GPT1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    138200
Section Bar
Section Bar
 Form/Format    Suspension in 1.2 M ammonium sulfate.
Section Bar
 Source    Porcine Heart
 CAS Number    9000-86-6
 E.C Number    2.6.1.2
 Appearance    Yellow-green suspension.
 Activity    1,990 U/mL(Dimension Clinical Chemistry System)
 Unit definition    One unit will catalyze the transamination of one micromole of L-alanine to alphaketoglutarate, forming L-glutamate and pyruvate, per minute at 37C and pH 7.4.
 Protein    7.8 mg/mL(Coomassie)
 Specific Activity    260 U/mg protein
    
    
 Contaminants    CPK <=0.1%
SGOT/AST <=0.5%
LDH<=0.1%
GLDH<=0.01%
Protease <=0.02%
 Handling    Handle as a potentially hazardous substance.
 Recovery    Resuspend thoroughly before sampling.
Section Bar
 Preparation and Storage    Storage temperature: 2-8C
Storage note: Do not freeze
Shipping Note: Cold pack
 Other Notes    Small volumes of GPT protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for GPT protein

   MyBioSource is the leading producer of Glutamate Pyruvate Transaminase/Alanine Transaminase (GPT/ALT), used in multi-analyte clinical chemistry controls and calibrators for major IVD manufacturers around the world.

Custom preparations, technical support, bulk quantities and aliquoting available.

The Alanine Aminotransferase (ALT) blood test is typically used to detect liver injury. It is often ordered in conjunction with Aspartate Aminotransferase (AST) or as part of a liver panel to screen for and/or help diagnose liver disease. AST and ALT are considered to be two of the most important tests to detect liver injury, although ALT is more specific than AST. Sometimes AST is compared directly to ALT and an AST/ALT ratio is calculated. This ratio may be used to distinguish between different causes of liver damage.

Elevated levels of Glutamate Pyruvate Transaminase/Alanine Transaminase (GPT/ALT) often suggest the existence of other medical problems such as alcoholic or viral hepatitis, congestive heart failure, liver damage, biliary duct problems, infectious mononucleosis, or myopathy.

Human GPT/ALT is an enzyme that catalyzes the reversible transfer of an amino group from alanine to a-ketoglutarate. Human Alanine Aminotransferase is found in serum and in various bodily tissues but is most commonly associated with the liver. Also called Serum Glutamate Pyruvate Transaminase (SGPT) or Alanine Aminotransferase (ALAT).
 Product Categories/Family for GPT protein    Proteins; Antigens; Enzymes; Standards/controls; Native Proteins; Alanine Aminotransferase (alt; Gpt)
NCBI/Uniprot data below describe general gene information for GPT. It may not necessarily be applicable to this product.
 NCBI GI #    1507680
 NCBI GeneID    2875
 NCBI Accession #    BAA01186.1 [Other Products]
Section Bar
 UniProt Secondary Accession #    P78398; Q93076; B0YJ18; D3DWM7 [Other Products]
 UniProt Related Accession #    P24298 [Other Products]
 Molecular Weight    ~100,000
Table BarTOPTable Bar
 NCBI Official Full Name    alanine aminotransferase, partial
 NCBI Official Synonym Full Names    glutamic-pyruvate transaminase (alanine aminotransferase)
 NCBI Official Symbol    GPT [Similar Products]
 NCBI Official Synonym Symbols   
AAT1; ALT1; GPT1
[Similar Products]
 NCBI Protein Information    alanine aminotransferase 1; GPT 1; glutamic-alanine transaminase 1; glutamic--alanine transaminase 1; glutamic--pyruvic transaminase 1; glutamate pyruvate transaminase 1
 UniProt Protein Name    Alanine aminotransferase 1
 UniProt Synonym Protein Names   
Glutamate pyruvate transaminase 1; GPT 1; Glutamic--alanine transaminase 1; Glutamic--pyruvic transaminase 1
 Protein Family    Alanine aminotransferase
 UniProt Gene Name    GPT [Similar Products]
 UniProt Synonym Gene Names    AAT1; GPT1; ALT1; GPT 1 [Similar Products]
 UniProt Entry Name    ALAT1_HUMAN
Section Bar
 NCBI Summary for GPT    This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009]
Section Bar
 UniProt Comments for GPT    GPT: Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.

Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; EC 2.6.1.2; Transferase

Chromosomal Location of Human Ortholog: 8q24.3

Cellular Component: cytosol

Molecular Function: alanine transaminase activity; pyridoxal phosphate binding

Biological Process: amino acid biosynthetic process; L-alanine catabolic process
Table BarTOPTable Bar
 Research Articles on GPT    1. Among patients with chronic HCV infection, daily consumption of filtered coffee may have a beneficial effect on the stabilization of ALT levels.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with GPT proteinPathways associated with GPT protein
 Reference Product  PubMed Publications
 PGP protein  >19 publications with GPT and PGP
 GOT2 protein  >4 publications with GPT and GOT2
 LDHB protein  >1 publications with GPT and LDHB
 LDHC protein  >1 publications with GPT and LDHC
 Products by Pathway  Pathway Diagram
 2-Oxocarboxylic Acid Metabolism Pathway antibodies  2-Oxocarboxylic Acid Metabolism Pathway Diagram
 2-Oxocarboxylic Acid Metabolism Pathway antibodies  2-Oxocarboxylic Acid Metabolism Pathway Diagram
 Alanine And Aspartate Metabolism Pathway antibodies  Alanine And Aspartate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Amino Acid Synthesis And Interconversion (transamination) Pathway antibodies  Amino Acid Synthesis And Interconversion (transamination) Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Biosynthesis Of Amino Acids Pathway antibodies  Biosynthesis Of Amino Acids Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
Diseases associated with GPT proteinOrgans/Tissues associated with GPT protein
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >918 publications with GPT and Liver Diseases
 Poisoning Antibodies  >374 publications with GPT and Poisoning
 Drug-Induced Liver Injury Antibodies  >347 publications with GPT and Drug-Induced Liver Injury
 Hepatitis Antibodies  >334 publications with GPT and Hepatitis
 Drug-Related Side Effects and Adverse Reactions Antibodies  >286 publications with GPT and Drug-Related Side Effects and Adverse Reactions
 Necrosis Antibodies  >259 publications with GPT and Necrosis
 Cardiovascular Diseases Antibodies  >215 publications with GPT and Cardiovascular Diseases
 Liver Neoplasms Antibodies  >170 publications with GPT and Liver Neoplasms
 Liver Cirrhosis Antibodies  >158 publications with GPT and Liver Cirrhosis
 Disease Models, Animal Antibodies  >151 publications with GPT and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1772 publications with GPT and Liver
 Kidney Antibodies  >349 publications with GPT and Kidney
 Heart Antibodies  >186 publications with GPT and Heart
 Lung Antibodies  >166 publications with GPT and Lung
 Brain Antibodies  >156 publications with GPT and Brain
 Skin Antibodies  >125 publications with GPT and Skin
 Intestine Antibodies  >87 publications with GPT and Intestine
 Mixed Antibodies  >75 publications with GPT and Mixed
 Stomach Antibodies  >59 publications with GPT and Stomach
 Pancreas Antibodies  >42 publications with GPT and Pancreas
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions