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ANXA2 protein :: Annexin A2 Protein

Scan QR to view Datasheet Catalog #    MBS634842 ANXA2 protein
Unit / Price
0.1 mg  /  $400 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Annexin A2 (ANXA2), Protein

 Also Known As   

Annexin A2 (ANXA2, annexin A2, ANX2, LIP2, LPC2, CAL1H, LPC2D, ANX2L4, P36, PAP-IV, annexin II, lipocortin II, Annexin II (lipocortin I), annexin II (lipocortin II), calpactin I, heavy polypeptide (p36), annexin II (lipocortin II calpactin I, heavy polype

 Product Synonym Names    Annexin A2 (ANXA2, annexin A2, ANX2, LIP2, LPC2, CAL1H, LPC2D, ANX2L4, P36, PAP-IV, annexin II, lipocortin II, Annexin II (lipocortin I), annexin II (lipocortin II), calpactin I, heavy polypeptide (p36), annexin II (lipocortin II calpactin I, heavy polype
 Product Gene Name   

ANXA2 protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 1; NC_010443.4 (123368568..123414399). Location: chromosome: 1
 3D Structure    ModBase 3D Structure for P19620
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 Purity/Purification    Highly Purified
Highly Purified
 Form/Format    Supplied as a lyophilized powder in PBS.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of ANXA2 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for ANXA2 protein

   STVHEILCKLSLEGD, N Terminus
 Product Categories/Family for ANXA2 protein    Molecular Biology; MB-Annexin
 Applications Tested/Suitable for ANXA2 protein   

ELISA (EL/EIA)

 Application Notes for ANXA2 protein    Suitable for use in Peptide ELISA.
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NCBI/Uniprot data below describe general gene information for ANXA2. It may not necessarily be applicable to this product.
 NCBI GI #    54020966
 NCBI GeneID    406192
 NCBI Accession #    NP_001005726.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001005726.1 [Other Products]
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 UniProt Primary Accession #    P19620 [Other Products]
 UniProt Secondary Accession #    Q5Y2C7 [Other Products]
 UniProt Related Accession #    P19620 [Other Products]
 Molecular Weight    38,534 Da [Similar Products]
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 NCBI Official Full Name    annexin A2
 NCBI Official Symbol    ANXA2 [Similar Products]
 NCBI Protein Information    annexin A2; p36; PAP-IV; annexin-2; protein I; annexin II; lipocortin II; chromobindin-8; calpactin I heavy chain; calpactin-1 heavy chain; placental anticoagulant protein IV
 UniProt Protein Name    Annexin A2
 UniProt Synonym Protein Names   
Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36
 Protein Family    Annexin
 UniProt Gene Name    ANXA2 [Similar Products]
 UniProt Synonym Gene Names    ANX2; PAP-IV [Similar Products]
 UniProt Entry Name    ANXA2_PIG
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 UniProt Comments for ANXA2    Function: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity.

Subunit structure: Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with ATP1B1 and DYSF

By similarity. Interacts with COCH

By similarity.

Subcellular location: Secreted › extracellular space › extracellular matrix › basement membrane. Melanosome

By similarity. Note: In the lamina beneath the plasma membrane.

Domain: A pair of annexin repeats may form one binding site for calcium and phospholipid.

Post-translational modification: ISGylated

By similarity.

Miscellaneous: It may cross-link plasma membrane phospholipids with actin and the cytoskeleton and be involved with exocytosis.

Sequence similarities: Belongs to the annexin family.Contains 4 annexin repeats.
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 Research Articles on ANXA2    1. An octameric model is proposed for the annexin A2/p11(S100A10) complex, which exerts annexin A2 function. The proposed structure of the annexin A2/p11 octamer sheds new light into annexin A2/p11 interaction.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ANXA2 proteinDiseases associated with ANXA2 protein
 Reference Product  PubMed Publications
 S100A10 protein  >30 publications with ANXA2 and S100A10
 ANXA1 protein  >14 publications with ANXA2 and ANXA1
 ANXA5 protein  >7 publications with ANXA2 and ANXA5
 VIM protein  >4 publications with ANXA2 and VIM
 S100A11 protein  >2 publications with ANXA2 and S100A11
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >78 publications with ANXA2 and Neoplasms
 Adenocarcinoma Antibodies  >20 publications with ANXA2 and Adenocarcinoma
 Inflammation Antibodies  >17 publications with ANXA2 and Inflammation
 Neoplasm Metastasis Antibodies  >16 publications with ANXA2 and Neoplasm Metastasis
 Cardiovascular Diseases Antibodies  >15 publications with ANXA2 and Cardiovascular Diseases
 Neoplasm Invasiveness Antibodies  >14 publications with ANXA2 and Neoplasm Invasiveness
 Carcinoma, Hepatocellular Antibodies  >14 publications with ANXA2 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >14 publications with ANXA2 and Liver Diseases
 Disease Models, Animal Antibodies  >13 publications with ANXA2 and Disease Models, Animal
 Necrosis Antibodies  >12 publications with ANXA2 and Necrosis
Organs/Tissues associated with ANXA2 protein
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >49 publications with ANXA2 and Blood
 Liver Antibodies  >23 publications with ANXA2 and Liver
 Lung Antibodies  >16 publications with ANXA2 and Lung
 Brain Antibodies  >13 publications with ANXA2 and Brain
 Muscle Antibodies  >11 publications with ANXA2 and Muscle
 Bone Marrow Antibodies  >10 publications with ANXA2 and Bone Marrow
 Prostate Antibodies  >9 publications with ANXA2 and Prostate
 Skin Antibodies  >7 publications with ANXA2 and Skin
 Intestine Antibodies  >7 publications with ANXA2 and Intestine
 Embryonic Tissue Antibodies  >7 publications with ANXA2 and Embryonic Tissue
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