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CRP protein :: C-Reactive Protein

Scan QR to view Datasheet Catalog #    MBS173367 CRP protein
Unit / Price
1 mg  /  $200 +1 FREE 8GB USB
5 mg  /  $470 +1 FREE 8GB USB
25 mg  /  $1,605 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

C-Reactive (CRP), Protein

★Popular Item★
 Also Known As   

C-Reactive Protein (CRP), Human Pleural Fluid

 Product Synonym Names    CRP; C-Reactive Protein (CRP), Human - >=99% (SDS-PAGE) - Lyophilized
 Product Gene Name   

CRP protein

[Similar Products]
 Product Synonym Gene Name    RP11-419N10.4; PTX1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS173367 COA    COA PDF
 OMIM    123260
 3D Structure    ModBase 3D Structure for P02741
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 Purity/Purification    >= 99% (SDS-PAGE)
 Form/Format    Lyophilized from sodium citrate pH 6.5 with polyethylene glycol and trehalose
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 Source    Human Pleural Fluid
 Appearance    White powder
 Solubility    Clear, Colorless (1mg protein/mL tris buffered saline with 5mM calcium chloride, pH 8.0)
 Protein    0.13mg protein/mg solid (E0.1%280 nm=1.8)
 Handling    Handle as a potentially hazardous substance.
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 Preparation and Storage    2-8C
Storage Note: Protect from moisture.
Shipping Note: Cold pack.
 Other Notes    Small volumes of CRP protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CRP protein

   MyBioSource is a major supplier of C-Reactive Protein (CRP) for medical research and diagnostic manufacturing. C-Reactive Protein is purified using multiple affinity chromotagraphy steps.

Custom preparations, technical support, bulk quantities and aliquoting available.

C-Reactive Protein (CRP) is a pentameric serum protein belonging to the pentraxin family that is comprised of five identical ~ 23kDa subunits. CRP is a positive acute phase reactant, the levels of which increase modestly in humans in response to inflammation, tissue injury or disease. The acute phase response develops in a wide range of acute and chronic inflammatory conditions like bacterial, viral, or fungal infections; rheumatic and other inflammatory diseases; malignancy; and tissue injury or necrosis.
 Product Categories/Family for CRP protein    Proteins; Antigens; Standards/controls; Native Proteins; Immunogen; C-reactive Protein (crp)
NCBI/Uniprot data below describe general gene information for CRP. It may not necessarily be applicable to this product.
 NCBI GI #    30224
 NCBI GeneID    1401
 NCBI Accession #    CAA39671.1 [Other Products]
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 UniProt Primary Accession #    P02741 [Other Products]
 UniProt Secondary Accession #    Q08AK3; Q8WW75; A8K078; D3DVD9; D3DVE0 [Other Products]
 UniProt Related Accession #    P02741 [Other Products]
 Molecular Weight    10,415 Da
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 NCBI Official Full Name    C-reactive protein
 NCBI Official Synonym Full Names    C-reactive protein, pentraxin-related
 NCBI Official Symbol    CRP [Similar Products]
 NCBI Official Synonym Symbols   
PTX1
[Similar Products]
 NCBI Protein Information    C-reactive protein; pentraxin 1
 UniProt Protein Name    C-reactive protein
 Protein Family    Cryparin
 UniProt Gene Name    CRP [Similar Products]
 UniProt Synonym Gene Names    PTX1 [Similar Products]
 UniProt Entry Name    CRP_HUMAN
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 NCBI Summary for CRP    The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]
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 UniProt Comments for CRP    CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: extracellular space; growth cone; extracellular region; filopodium

Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; cholesterol binding; virion binding; low-density lipoprotein binding; calcium ion binding

Biological Process: protein polymerization; wound healing; defense response to Gram-positive bacterium; response to ethanol; negative regulation of vasodilation; positive regulation of superoxide release; response to lead ion; response to hypoxia; acute-phase response; opsonization; inflammatory response; complement activation, classical pathway; aging
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 Research Articles on CRP    1. Serum CRP level was significantly related to TNM stage.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CRP proteinPathways associated with CRP protein
 Reference Product  PubMed Publications
 ICAM1 protein  >493 publications with CRP and ICAM1
 IL6 protein  >479 publications with CRP and IL6
 SERPINE1 protein  >319 publications with CRP and SERPINE1
 STAT3 protein  >36 publications with CRP and STAT3
 CFH protein  >23 publications with CRP and CFH
 LEP protein  >9 publications with CRP and LEP
 FCGR2A protein  >7 publications with CRP and FCGR2A
 FN1 protein  >2 publications with CRP and FN1
 Products by Pathway  Pathway Diagram
 Classical Antibody-mediated Complement Activation Pathway antibodies  Classical Antibody-mediated Complement Activation Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Creation Of C4 And C2 Activators Pathway antibodies  Creation Of C4 And C2 Activators Pathway Diagram
 IL6-mediated Signaling Events Pathway antibodies  IL6-mediated Signaling Events Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
Diseases associated with CRP proteinOrgans/Tissues associated with CRP protein
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >11556 publications with CRP and Inflammation
 Cardiovascular Diseases Antibodies  >8490 publications with CRP and Cardiovascular Diseases
 Infection Antibodies  >4586 publications with CRP and Infection
 Heart Diseases Antibodies  >4057 publications with CRP and Heart Diseases
 Metabolic Diseases Antibodies  >3825 publications with CRP and Metabolic Diseases
 Myocardial Ischemia Antibodies  >3255 publications with CRP and Myocardial Ischemia
 Necrosis Antibodies  >3225 publications with CRP and Necrosis
 Atherosclerosis Antibodies  >2879 publications with CRP and Atherosclerosis
 Arthritis, Rheumatoid Antibodies  >2026 publications with CRP and Arthritis, Rheumatoid
 Pain Antibodies  >2014 publications with CRP and Pain
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1426 publications with CRP and Liver
 Pancreas Antibodies  >148 publications with CRP and Pancreas
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