Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Protein rightarrow CD273  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • 6-keto-PGF1-alpha Antibody
 • Complement fragment 5a, C5a ELISA Kit
 • NGLY1 Antibody
 • Glutathione (GSH) ELISA Kit
 • Carboxylesterase 1C (EST1C) Recombinant Protein
 • Cell Division Cycle 42 (CDC42) Recombinant Protein
 • GP-73 ELISA Kit
 • GBE1 Antibody
 • soluble vascular endothelial growth factor receptor 2 (sVEGF... ELISA Kit
 • Complement C3b, inactivated Antibody
 • Steroid 5 Alpha Reductase 2 (SRD5a2) ELISA Kit
 • TGFbeta RII Antibody
 • Serum Amyloid A (rmSAA1) Recombinant Protein
 • choline kinase alpha (CHKA) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

CD273 protein

Scan QR to view Datasheet Catalog #    MBS666852
Testing Data
Unit / Price
0.025 mg  /  $575 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD273, Protein

 Also Known As   

CD273-muIg-Biotin

 Product Synonym Names    Human CD273(B7-DC,)-muIg/Biotin Fusion Protein
 Product Gene Name   

CD273 protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    (221)gtepr gptikpcppc kcpapnllgg psvfifppki kdvlmislsp ivtcvvvdvs eddpdvqisw fvnnvevhta qtqthredyn stlrvvsalp iqhqdwmsgk efkckvnnkd lpapiertis kpgsvrapqv yvlpppeeem tkkqvtvtcm vtdfmpediy vewtnngkte lnykntepvl dsdgsyfmys klgvekknwv ernsyscsvv heglhnhhtt ksfsrtpg(4 55) Predic ted monomeric (non glycosylat ed) molecular weight: 49 kd. The molecule is dimeric and runs at ~135 kd in SDS-PAGE under native conditions , and ~74 kd reduced
(20)lftvt vpkelyiieh gsnvtlecnf dtgshvnlga itaslqkven dtsphrerat lleeqlplgk asfhipqvqv rdegqyqcii iygvawdyky ltlkvkasyr kinthilkvp etdeveltcq atyplaevsw pnvsvpants hsrtpeglyq vtsvlrlkpp pgrnfscvfw nthvreltla sidlqsqmep rthpt (220 )
Section Bar
 Host    CHO cells
 Species Reactivity    Human
Section Bar
 Form/Format    50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA.
 Concentration    0.5 mg/ml (lot specific)
Section Bar
 Transfectant Cell Line    CHO
 Performance    CD273-muIg/Biotin is functional in EIA as a detection reagent binding to plate-coated recombinant CD279(PD-1). Streptavidin/HRP was used as a secondary detector and TMB/H2 O2 as a chromagen/substrate.
 Conjugation    Biotin
 Production    Human CD274-muIg fusion protein was Protein A purified from (low FBS containing) tissue culture supernatant of CHO transfectants, and reacted with NHS-Biotin. Unconjugated Biotin was removed from conjugate by desalting column.
 Buffer    50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Section Bar
 Preparation and Storage    Store at 2 - 5 degree C. Freeze/Thawing is not recommended.
Product should retain activity for at least 6 months after shipping date when stored as recommended.
 Other Notes    Small volumes of CD273 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for CD273 protein

   Information: CD273 (B7-DC, PCDL-2, Programmed cell death ligand 2, Butyrophilin-like protein) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by Dendritic cells.and provides a stimulatory signal to CD279 (PD-1, Programmed Death molecule) which serves an important immunoregulatory role by down regulating T cell response. CD273 binds to CD279(PD-1) with a 2- 6 fold higher affinity than CD274(2). Recombinant CD273-muIg binds to recombinant CD279 in EIA.
 Applications Tested/Suitable for CD273 protein   

ELISA (EIA)

Section Bar
 Testing Data of CD273 protein    CD273 protein Testing Data image
Table BarTOPTable Bar
 

Product References and Citations for CD273 protein

   1) E N Rozali, W J Lesterhuis, et al. (2012) Clin Develop Immunol 2012: 656340. 2) P Youngnak, H Konozo, et al. (2003) Biochemical and Biophysical Research Communications 307(3): 672-677.
Section Bar
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions