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HPR protein :: Haptoglobin Protein

Scan QR to view Datasheet Catalog #    MBS173103 HPR protein
Unit / Price
0.01 mg  /  $155 +1 FREE 8GB USB
0.1 mg  /  $390 +1 FREE 8GB USB
1 mg  /  $1,230 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Haptoglobin (HPR), Protein

★Popular Item★
 Also Known As   

Haptoglobin, Rat Serum

 Product Synonym Names    Haptoglobin (Hp), Rat
 Product Gene Name   

HPR protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    140210
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 Purity/Purification    >= 95% (SDS-PAGE)
 Form/Format    Liquid
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 Source    Rat Serum
 Recertification    2 years
 Protein    > 0.5 mg/mL (Bradford v. BSA)
 Preservatives    0.05% Sodium Azide
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 Preparation and Storage    At -20 degree C
 Other Notes    Small volumes of HPR protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for HPR protein    Proteins; Antigens; Standards/controls; Native Proteins; Haptoglobin (hp)
NCBI/Uniprot data below describe general gene information for HPR. It may not necessarily be applicable to this product.
 NCBI GI #    184321
 NCBI GeneID    3250
 NCBI Accession #    AAA52686.1 [Other Products]
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 UniProt Secondary Accession #    Q7LE20; Q92658; Q92659; Q9ULB0 [Other Products]
 UniProt Related Accession #    P00739 [Other Products]
 Molecular Weight    43,078 Da [Similar Products]
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 NCBI Official Full Name    haptoglobin, partial
 NCBI Official Synonym Full Names    haptoglobin-related protein
 NCBI Official Symbol    HPR [Similar Products]
 NCBI Official Synonym Symbols   
HP; A-259H10.2
[Similar Products]
 NCBI Protein Information    haptoglobin-related protein; Haptoglobin-related locus
 UniProt Protein Name    Haptoglobin-related protein
 Protein Family    Haptoglobin
 UniProt Gene Name    HPR [Similar Products]
 UniProt Entry Name    HPTR_HUMAN
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 NCBI Summary for HPR    This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]
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 UniProt Comments for HPR    HPR: a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: extracellular region

Molecular Function: hemoglobin binding; catalytic activity

Biological Process: receptor-mediated endocytosis; metabolic process
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 Research Articles on HPR    1. Our analysis illustrates the complex interplay between functions and haplotypes of adjacent genes, environmental context and natural selection, and offers insights into potential use of haptoglobin or haptoglobin-related protein as therapeutic agents.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HPR proteinPathways associated with HPR protein
 Reference Product  PubMed Publications
 HBD protein  >4 publications with HPR and HBD
 APOA1 protein  >3 publications with HPR and APOA1
 ASGR1 protein  >1 publications with HPR and ASGR1
 IL6 protein  >1 publications with HPR and IL6
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Scavenging Of Heme From Plasma Pathway antibodies  Scavenging Of Heme From Plasma Pathway Diagram
Diseases associated with HPR proteinOrgans/Tissues associated with HPR protein
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >122 publications with HPR and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >92 publications with HPR and Neoplasms, Experimental
 Heart Diseases Antibodies  >80 publications with HPR and Heart Diseases
 Mammary Neoplasms, Animal Antibodies  >44 publications with HPR and Mammary Neoplasms, Animal
 Ovarian Neoplasms Antibodies  >37 publications with HPR and Ovarian Neoplasms
 Kidney Diseases Antibodies  >35 publications with HPR and Kidney Diseases
 Immune System Diseases Antibodies  >30 publications with HPR and Immune System Diseases
 Liver Neoplasms Antibodies  >24 publications with HPR and Liver Neoplasms
 Cell Transformation, Neoplastic Antibodies  >21 publications with HPR and Cell Transformation, Neoplastic
 Inflammation Antibodies  >21 publications with HPR and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >78 publications with HPR and Liver
 Brain Antibodies  >52 publications with HPR and Brain
 Heart Antibodies  >51 publications with HPR and Heart
 Lung Antibodies  >50 publications with HPR and Lung
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